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Effects of acetylation on human insulin structure, and dynamics at different temperatures: A molecular dynamics simulation study
Effects of acetylation on human insulin structure, and dynamics at different temperatures: A molecular dynamics simulation study
Insulin was used as a model protein to investigate the effects of acetylation, a significant post-translational modificati...
A comparative study of low-pH tolerance and chitinase activity between toxigenic and non-toxigenic strains of
A comparative study of low-pH tolerance and chitinase activity between toxigenic and non-toxigenic strains of
Survival of toxigenic and non-toxigenic strains of Vibrio cholerae involves adaptation to varying pH conditions, a mechani...
Response of mycorrhizal fungal communities to tree species composition and soil properties in the Miombo subtropical dry forest
Response of mycorrhizal fungal communities to tree species composition and soil properties in the Miombo subtropical dry forest
Miombo forests are ecologically and economically important; however, knowledge about mycorrhizal assemblages harboured by ...
Computational insights into cancer stem cell dynamics and the urokinase plasminogen activation pathway
Computational insights into cancer stem cell dynamics and the urokinase plasminogen activation pathway
This study introduces a novel computational model that integrates cancer stem cells (CSCs) and the plasminogen activation ...
Structure evaluation coupled with all-atom molecular dynamics and advanced quantum mechanical DFT revealed kaempferol as a potent binding flavonol for the epigenetic-target HDAC9
Structure evaluation coupled with all-atom molecular dynamics and advanced quantum mechanical DFT revealed kaempferol as a potent binding flavonol for the epigenetic-target HDAC9
Aberrant histone deacetylase-9 (HDAC9) activity has been recorded in a plethora of malignant tumors, including gastric can...
Cardiometabolomic signatures and gut microbiota dynamics in perinatally undernourished F offspring: Decoding the metabolic footprint
Cardiometabolomic signatures and gut microbiota dynamics in perinatally undernourished F offspring: Decoding the metabolic footprint
The Developmental Origins of Health and Disease (DOHaD) hypothesis asserts that detrimental prenatal conditions, such as d...
Temporal and spatial patterns of leaf unrolling in
Temporal and spatial patterns of leaf unrolling in
The processes of cellular differentiation and tissue maturation in the early phases of leaf development have been...
Dynamic attributes of the pedicel: Key drivers, structure and function in angiosperms
Dynamic attributes of the pedicel: Key drivers, structure and function in angiosperms
Pedicels, the short specialized stems that support reproductive structures in flowering plants, play diverse roles through...
Distinct macrophage and microglia function in ischemic stroke
Distinct macrophage and microglia function in ischemic stroke
This study aims to explore the characteristics and differentiation pathways of microglia and macrophages using single-cell...
Hypercholesterolemia-induced impairment in sorafenib functionality is overcome by avasimibe co-treatment
Hypercholesterolemia-induced impairment in sorafenib functionality is overcome by avasimibe co-treatment
Avasimibe, a cholesterol-lowering drug with proven safety in clinical trials, has also been repositioned as an anticancer ...
Expression of Nischarin increases with postnatal hippocampal maturation and regulates cofilin phosphorylation
Expression of Nischarin increases with postnatal hippocampal maturation and regulates cofilin phosphorylation
The hippocampus, critical for memory integration and synaptic plasticity, undergoes cytoskeletal reorganization during dev...
Cross-sectional associations between plasma copper, zinc and prediabetes among rural Indian adolescent girls: baseline data from the DERVAN cohort (DERVAN-8)
Cross-sectional associations between plasma copper, zinc and prediabetes among rural Indian adolescent girls: baseline data from the DERVAN cohort (DERVAN-8)
Copper and zinc are essential minerals for proper metabolic function, and their imbalance could potentially cause prediabe...
Delta-9-tetrahydrocannabinol delineates D-galactose and aluminium chloride-induced cognitive dysfunction and neurodegeneration in the hippocampus of the Wistar rat model
Delta-9-tetrahydrocannabinol delineates D-galactose and aluminium chloride-induced cognitive dysfunction and neurodegeneration in the hippocampus of the Wistar rat model
Alzheimer’s disease (AD) is a neurodegenerative disorder characterised by neurodegeneration and a decline in cogniti...
Evaluation of insecticide susceptibility variation in different field populations of the cabbage aphid, (Hemiptera: Aphididae), to selected organophosphate insecticides
Evaluation of insecticide susceptibility variation in different field populations of the cabbage aphid, (Hemiptera: Aphididae), to selected organophosphate insecticides
Brevicoryne brassicae (Linnaeus), the cabbage aphid, is a destructive pest of cruciferous crops worldwide. In Kashmir, man...
Exploring the functional roles of secondary metabolites in defense networks
Exploring the functional roles of secondary metabolites in defense networks
Plants produce an array of secondary metabolites (SMs) to cope with diverse environmental and pathogenic challenges. Brass...
PPE18 protein of downregulates LPS-induced IgG production by inhibiting nitric oxide synthesis
PPE18 protein of downregulates LPS-induced IgG production by inhibiting nitric oxide synthesis
Mycobacterial PPE18 is a virulence factor. Previous studies have demonstrated that recombinant PPE18 protein (rPPE18) down...
Bite size of regulates feeding, satiety and development on a diet of live yeast
Bite size of regulates feeding, satiety and development on a diet of live yeast
In the wild, the nematode Caenorhabditis elegans primarily feeds on microbes, which are abundant in rotting vegetation. St...
Role of the extracellular matrix in amylin aggregation: Opportunities for improved therapy in type 2 diabetes mellitus
Role of the extracellular matrix in amylin aggregation: Opportunities for improved therapy in type 2 diabetes mellitus
Abedini A and Raleigh DP 2006 Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative a...
Surviving deadly radiation: Lessons from tardigrades
Surviving deadly radiation: Lessons from tardigrades
Anoud M, Delagoutte E, Helleu Q, et al. 2024 Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding pr...
CroPCS: Crop Plants Combined Stress Knowledgebase
CroPCS: Crop Plants Combined Stress Knowledgebase
Plants, being sessile organisms, are continually exposed to diverse combinations of biotic and abiotic stresses in their n...
Modulation of the biphasic pattern of cortical reorganization in spinal cord-transected rats by external magnetic fields
Modulation of the biphasic pattern of cortical reorganization in spinal cord-transected rats by external magnetic fields
A biphasic pattern of reorganization in the somatosensory cortical area, representing the hindlimb or forelimb, has been s...
Localization of mitochondria along axons and at synapses in touch receptor neurons is necessary for touch habituation
Localization of mitochondria along axons and at synapses in touch receptor neurons is necessary for touch habituation
Neuronal mitochondria are important for neuronal survival and function. Mitochondria buffer calcium, produce ATP, and cont...
Life history traits and spatial characteristics of an Asia Minor thin-toed gecko population ( Blanford, 1874)
Life history traits and spatial characteristics of an Asia Minor thin-toed gecko population ( Blanford, 1874)
The aim of the present study was to obtain information on certain life history traits such as life span and age of sexual ...
Computational identification of perturbed pathways in type 2 diabetes mellitus patients reveals necroptosis and NF-κB pathways with potential for susceptibility to psoriasis
Computational identification of perturbed pathways in type 2 diabetes mellitus patients reveals necroptosis and NF-κB pathways with potential for susceptibility to psoriasis
Psoriasis (PS) is one of the comorbidities of type 2 diabetes mellitus (T2DM). The molecular processes leading to the T2DM...
Epigenetic regulation of histone 3 acetylation and p53 by SIRT1 overexpression in an experimental model of alveolar epithelium damage
Epigenetic regulation of histone 3 acetylation and p53 by SIRT1 overexpression in an experimental model of alveolar epithelium damage
Pulmonary fibrosis is a chronic, life-threatening respiratory disease characterized by high incidence and lack of effectiv...
Spindle localization of YAP/TAZ maintains even distribution of YAP/TAZ in daughter cells
Spindle localization of YAP/TAZ maintains even distribution of YAP/TAZ in daughter cells
YAP and TAZ are downstream effectors of the Hippo signaling pathway, known to shuttle between the cytoplasm and nucleus, w...
Comparisons between young, aged, and Alzheimer’s brains reveal specific expression patterns for a subset of transposons and satellite repeats
Comparisons between young, aged, and Alzheimer’s brains reveal specific expression patterns for a subset of transposons and satellite repeats
Recent studies have highlighted the involvement of repeat-derived transcripts in the pathological transcriptome of Alzheim...
Latitudinal patterns of flowering phenology of three widespread tropical species from public media and data repositories
Latitudinal patterns of flowering phenology of three widespread tropical species from public media and data repositories
Plant phenology encompasses the study of periodic events in the biological life cycles of plants and the influence of seas...
Genetic insights into species: A comparative transcriptomic analysis
Genetic insights into species: A comparative transcriptomic analysis
Hippeastrum species and their hybrids, valued for their vibrant flowers and ease of cultivation, are significant in the or...
Croquemort-scavenger receptor class B 2 () gene in : Molecular characterization and expression analysis after blood feeding
Croquemort-scavenger receptor class B 2 () gene in : Molecular characterization and expression analysis after blood feeding
SCRBQ2 is a croquemort-scavenger receptor class B family protein. The identification of SCRBQ2 in the detergent-resistant ...
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