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VEGFA is essential for the potentiation of ATRA on BMP9-induced osteogenesis of preadipocytes and osteoporotic fracture healing
VEGFA is essential for the potentiation of ATRA on BMP9-induced osteogenesis of preadipocytes and osteoporotic fracture healing
The induction of osteogenic differentiation in preadipocytes may serve as a potential therapeutic approach for treating os...
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
Stress is a key trigger of gastric dysmotility, partly via mitochondrial dysfunction and disordered gut–brain hormon...
Comparative pathophysiological modeling: the advantage of “two-hit” over “one-hit” in acute liver failure studies
Comparative pathophysiological modeling: the advantage of “two-hit” over “one-hit” in acute liver failure studies
Acute liver failure (ALF), a life-threatening condition marked by rapid hepatocyte death and systemic inflammation, poses ...
A preliminary study on the mechanism of stromal interaction molecule 1 (STIM1) involvement in Adriamycin-induced podocyte injury
A preliminary study on the mechanism of stromal interaction molecule 1 (STIM1) involvement in Adriamycin-induced podocyte injury
Cellular metabolic reprogramming is intimately linked to various physiological and pathological processes. For instance, c...
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling
Intervertebral disc degeneration (IVDD), a natural aging process, leads to intervertebral disc pain, with lumbar resection...
miR-495-3p attenuates cerebral ischemia-reperfusion-induced neuronal inflammation and apoptosis by targeting CCL2 expression
miR-495-3p attenuates cerebral ischemia-reperfusion-induced neuronal inflammation and apoptosis by targeting CCL2 expression
This study aimed to explore the function of miR-495-3p in cerebral ischemia-reperfusion injury (CI/RI) and reveal its pote...
Construction of tissue-engineered vascular sinoatrial node in vitro
Construction of tissue-engineered vascular sinoatrial node in vitro
To develop a biological pacemaker by differentiating rabbit BMSCs into vascular endothelial cells (VECs) and pacemaker-lik...
Decorin inhibits the migration and invasion of the LPS + high glucose–induced primary trophoblast cell through ADAMTS12
Decorin inhibits the migration and invasion of the LPS + high glucose–induced primary trophoblast cell through ADAMTS12
Decorin was identified as the most relevant biomarker in type 2 diabetes or obesity-related diseases, but its function in ...
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis
The objective of this article is to explore the influence and process by which periodontitis affects the metastasis of gas...
miR-3614-5p prevents endothelial differentiation and angiogenesis in human exfoliated deciduous teeth by targeting lysophosphatidic acid receptor 2
miR-3614-5p prevents endothelial differentiation and angiogenesis in human exfoliated deciduous teeth by targeting lysophosphatidic acid receptor 2
The contribution of microRNAs (miRNAs) to the endothelial differentiation of stem cells from human exfoliated deciduous te...
Elevated intravesical pressure promotes circulating tumor cell release in an orthotopic mouse model of bladder cancer
Elevated intravesical pressure promotes circulating tumor cell release in an orthotopic mouse model of bladder cancer
Elevated intravesical pressure during transurethral resection of bladder tumor (TURBT) is hypothesized to facilitate the r...
Ginsenoside F1 ameliorates nonalcoholic fatty liver disease by activating the AMPK/PGC-1α pathway and autophagy
Ginsenoside F1 ameliorates nonalcoholic fatty liver disease by activating the AMPK/PGC-1α pathway and autophagy
Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases globally, and currently, the...
In vitro culture for long-term maintenance of embryonic insect cells from the house cricket
In vitro culture for long-term maintenance of embryonic insect cells from the house cricket
Insect cell culture has become foundational for many areas of research and biotechnological innovation, yet major taxonomi...
Correction: The effect of IGF-1 on cartilage injury in bone marrow mesenchymal stem cells through the BMP2-Smad1/5 signaling pathway
Correction: The effect of IGF-1 on cartilage injury in bone marrow mesenchymal stem cells through the BMP2-Smad1/5 signaling pathway
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License...
Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish () cell models
Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish () cell models
Graphene and its derivatives have been increasingly explored for various biomedical applications. Despite their promising ...
Cabozantinib activates TFEB-mediated autophagy to exert anti-tumor effects in hepatocellular carcinoma
Cabozantinib activates TFEB-mediated autophagy to exert anti-tumor effects in hepatocellular carcinoma
Autophagy signaling plays a crucial yet complex role in hepatocellular carcinoma (HCC), influencing tumor progression and ...
RYK silencing-modified bone marrow-derived mesenchymal stem cells suppress gastric cancer progression
RYK silencing-modified bone marrow-derived mesenchymal stem cells suppress gastric cancer progression
Gastric cancer (GC) is a prevalent malignant tumor threatening human health. This study aimed to explore the potential mec...
Oncogenic role and potential mechanisms of MYO1B in breast cancer
Oncogenic role and potential mechanisms of MYO1B in breast cancer
Myosin IB (MYO1B), a member of the type I myosin family, is overexpressed in various tumor tissues. MYO1B facilitates tumo...
Establishment and characterization of air–liquid interface cultures of human small airway epithelial cells from two commercial sources
Establishment and characterization of air–liquid interface cultures of human small airway epithelial cells from two commercial sources
Albano GD, Montalbano AM, Gagliardo R, Anzalone G, Profita M (2022) Impact of air pollution in airway diseases: role of ep...
Pro-myogenic and anti-atrophic effects of extract through Akt/mTOR signaling in dexamethasone-induced C2C12 cells and zebrafish model
Pro-myogenic and anti-atrophic effects of extract through Akt/mTOR signaling in dexamethasone-induced C2C12 cells and zebrafish model
Muscle atrophy, which is characterized by the loss and dysfunction of skeletal muscle proteins, is a major degenerative co...
Highly conserved and extremely evolvable: BMP signalling in secondary axis patterning of Cnidaria and Bilateria
Highly conserved and extremely evolvable: BMP signalling in secondary axis patterning of Cnidaria and Bilateria
Bilateria encompass the vast majority of the animal phyla. As the name states, they are bilaterally symmetric, that is wit...
Unveiling the cell dynamics during the final shape formation of the tarsus in adult leg by live imaging
Unveiling the cell dynamics during the final shape formation of the tarsus in adult leg by live imaging
Organisms display a remarkable diversity in their shapes. Although substantial progress has been made in unraveling the me...
Silencing of blocks tail regeneration, but does not induce head regeneration in the flatworm
Silencing of blocks tail regeneration, but does not induce head regeneration in the flatworm
β-Catenin has two major functions conserved across metazoans. It enables the interaction of classical cadherin with a...
Sex-type specification and meristem development in fern gametophytes
Sex-type specification and meristem development in fern gametophytes
Sex determination, involving the physiological and morphological separation of male and female gamete-producing structures...
expression in the protonephridial system and foot neurons of the rotifer
expression in the protonephridial system and foot neurons of the rotifer
The homeobox gene engrailed is a multifunctional regulator with diverse developmental roles across Bilateria, ranging from...
Mapping micromere fate in the clitellate annelid
Mapping micromere fate in the clitellate annelid
In spiralians, the relationship between early cleavage patterns and the establishment of the juvenile body plan remains on...
culture studies and the effect of ZnO and CuO nanoparticles on total phenolic content expression in
culture studies and the effect of ZnO and CuO nanoparticles on total phenolic content expression in
In vitro cultures have the potential to serve as bio-factories for the production of secondary metabolites when stimulated...
proliferation of G. Forst. and (DC.) Burret as a source to produce bioactive phenolic compounds
proliferation of G. Forst. and (DC.) Burret as a source to produce bioactive phenolic compounds
In vitro culture enables the propagation and sustainable production of bioactive compounds in native plants. In Chile, Ber...
Optimizing efficient and reproducible regeneration shoot organogenesis and somatic embryogenesis from leaf and nodal explants of Royle ex Benth.—a highly valued medicinal herb of the Himalayas
Optimizing efficient and reproducible regeneration shoot organogenesis and somatic embryogenesis from leaf and nodal explants of Royle ex Benth.—a highly valued medicinal herb of the Himalayas
Phlomis bracteosa is an essential medicinal herb native to the Himalayas and is currently facing an alarming decline in it...
Chitosan-mediated enhanced hypericin biosynthesis in St. John’s wort () hairy root cultures
Chitosan-mediated enhanced hypericin biosynthesis in St. John’s wort () hairy root cultures
A targeted approach to enhance hypericin biosynthesis in Hypericum perforatum hairy root cultures through strategic select...
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