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VEGFA is essential for the potentiation of ATRA on BMP9-induced osteogenesis of preadipocytes and osteoporotic fracture healing
VEGFA is essential for the potentiation of ATRA on BMP9-induced osteogenesis of preadipocytes and osteoporotic fracture healing
The induction of osteogenic differentiation in preadipocytes may serve as a potential therapeutic approach for treating os...
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
Stress is a key trigger of gastric dysmotility, partly via mitochondrial dysfunction and disordered gut–brain hormon...
Comparative pathophysiological modeling: the advantage of “two-hit” over “one-hit” in acute liver failure studies
Comparative pathophysiological modeling: the advantage of “two-hit” over “one-hit” in acute liver failure studies
Acute liver failure (ALF), a life-threatening condition marked by rapid hepatocyte death and systemic inflammation, poses ...
A preliminary study on the mechanism of stromal interaction molecule 1 (STIM1) involvement in Adriamycin-induced podocyte injury
A preliminary study on the mechanism of stromal interaction molecule 1 (STIM1) involvement in Adriamycin-induced podocyte injury
Cellular metabolic reprogramming is intimately linked to various physiological and pathological processes. For instance, c...
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling
Intervertebral disc degeneration (IVDD), a natural aging process, leads to intervertebral disc pain, with lumbar resection...
miR-495-3p attenuates cerebral ischemia-reperfusion-induced neuronal inflammation and apoptosis by targeting CCL2 expression
miR-495-3p attenuates cerebral ischemia-reperfusion-induced neuronal inflammation and apoptosis by targeting CCL2 expression
This study aimed to explore the function of miR-495-3p in cerebral ischemia-reperfusion injury (CI/RI) and reveal its pote...
Construction of tissue-engineered vascular sinoatrial node in vitro
Construction of tissue-engineered vascular sinoatrial node in vitro
To develop a biological pacemaker by differentiating rabbit BMSCs into vascular endothelial cells (VECs) and pacemaker-lik...
Decorin inhibits the migration and invasion of the LPS + high glucose–induced primary trophoblast cell through ADAMTS12
Decorin inhibits the migration and invasion of the LPS + high glucose–induced primary trophoblast cell through ADAMTS12
Decorin was identified as the most relevant biomarker in type 2 diabetes or obesity-related diseases, but its function in ...
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis
The objective of this article is to explore the influence and process by which periodontitis affects the metastasis of gas...
miR-3614-5p prevents endothelial differentiation and angiogenesis in human exfoliated deciduous teeth by targeting lysophosphatidic acid receptor 2
miR-3614-5p prevents endothelial differentiation and angiogenesis in human exfoliated deciduous teeth by targeting lysophosphatidic acid receptor 2
The contribution of microRNAs (miRNAs) to the endothelial differentiation of stem cells from human exfoliated deciduous te...
Elevated intravesical pressure promotes circulating tumor cell release in an orthotopic mouse model of bladder cancer
Elevated intravesical pressure promotes circulating tumor cell release in an orthotopic mouse model of bladder cancer
Elevated intravesical pressure during transurethral resection of bladder tumor (TURBT) is hypothesized to facilitate the r...
Ginsenoside F1 ameliorates nonalcoholic fatty liver disease by activating the AMPK/PGC-1α pathway and autophagy
Ginsenoside F1 ameliorates nonalcoholic fatty liver disease by activating the AMPK/PGC-1α pathway and autophagy
Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases globally, and currently, the...
In vitro culture for long-term maintenance of embryonic insect cells from the house cricket
In vitro culture for long-term maintenance of embryonic insect cells from the house cricket
Insect cell culture has become foundational for many areas of research and biotechnological innovation, yet major taxonomi...
Correction: The effect of IGF-1 on cartilage injury in bone marrow mesenchymal stem cells through the BMP2-Smad1/5 signaling pathway
Correction: The effect of IGF-1 on cartilage injury in bone marrow mesenchymal stem cells through the BMP2-Smad1/5 signaling pathway
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License...
Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish () cell models
Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish () cell models
Graphene and its derivatives have been increasingly explored for various biomedical applications. Despite their promising ...
Cabozantinib activates TFEB-mediated autophagy to exert anti-tumor effects in hepatocellular carcinoma
Cabozantinib activates TFEB-mediated autophagy to exert anti-tumor effects in hepatocellular carcinoma
Autophagy signaling plays a crucial yet complex role in hepatocellular carcinoma (HCC), influencing tumor progression and ...
RYK silencing-modified bone marrow-derived mesenchymal stem cells suppress gastric cancer progression
RYK silencing-modified bone marrow-derived mesenchymal stem cells suppress gastric cancer progression
Gastric cancer (GC) is a prevalent malignant tumor threatening human health. This study aimed to explore the potential mec...
Oncogenic role and potential mechanisms of MYO1B in breast cancer
Oncogenic role and potential mechanisms of MYO1B in breast cancer
Myosin IB (MYO1B), a member of the type I myosin family, is overexpressed in various tumor tissues. MYO1B facilitates tumo...
Establishment and characterization of air–liquid interface cultures of human small airway epithelial cells from two commercial sources
Establishment and characterization of air–liquid interface cultures of human small airway epithelial cells from two commercial sources
Albano GD, Montalbano AM, Gagliardo R, Anzalone G, Profita M (2022) Impact of air pollution in airway diseases: role of ep...
Pro-myogenic and anti-atrophic effects of extract through Akt/mTOR signaling in dexamethasone-induced C2C12 cells and zebrafish model
Pro-myogenic and anti-atrophic effects of extract through Akt/mTOR signaling in dexamethasone-induced C2C12 cells and zebrafish model
Muscle atrophy, which is characterized by the loss and dysfunction of skeletal muscle proteins, is a major degenerative co...
Adhesion extracellular matrix proteins improve in vitro cellular and functional properties of enriched caprine adult dermal fibroblast
Adhesion extracellular matrix proteins improve in vitro cellular and functional properties of enriched caprine adult dermal fibroblast
Fibroblast cells have attracted significant interest because of their wide range of a...
Establishment of a method to evaluate the dynamics of highly chemotactic THP-1 cells during differentiation into monocyte-M1 macrophage-like cells
Establishment of a method to evaluate the dynamics of highly chemotactic THP-1 cells during differentiation into monocyte-M1 macrophage-like cells
Differentiation of the human monocytic leukemia cell line THP-1 is widely used to analyze the function of monocyte/macroph...
Exploring the effects of roscovitine, serum starvation, and contact inhibition at G/G arrest in northern tiger cat dermal fibroblasts
Exploring the effects of roscovitine, serum starvation, and contact inhibition at G/G arrest in northern tiger cat dermal fibroblasts
Nuclear reprogramming studies are important tools in conserving wild felids, with efficacy depending on efficient G0/G1 ce...
Nuclear protein 1 protects against neonatal hypoxic-ischemic encephalopathy by inhibiting neuronal ferroptosis by improving iron storage
Nuclear protein 1 protects against neonatal hypoxic-ischemic encephalopathy by inhibiting neuronal ferroptosis by improving iron storage
Recent studies have highlighted the role of ferroptosis in neuronal damage during neonatal hypoxic-ischemic encephalopathy...
Therapeutic potential of miR-10a overexpressing mesenchymal stem cell–derived extracellular vesicles in modulating inflammation in collagen-induced arthritis
Therapeutic potential of miR-10a overexpressing mesenchymal stem cell–derived extracellular vesicles in modulating inflammation in collagen-induced arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune condition that leads to joint damage. Mesenchymal stem cells (MSCs) are ...
Optimization of a protocol for the high-yield isolation of active muscle stem cells from bovine skeletal muscle tissue
Optimization of a protocol for the high-yield isolation of active muscle stem cells from bovine skeletal muscle tissue
Beef is primarily made up of skeletal muscle tissue. Therefore, the cultivation of bovine muscle stem cells (MSCs) to prov...
KHDRBS3-mediated upregulation of circ_0024107 in gastric cancer cells and GC-MSCs synergistically drives gastric cancer cell migration and invasion
KHDRBS3-mediated upregulation of circ_0024107 in gastric cancer cells and GC-MSCs synergistically drives gastric cancer cell migration and invasion
Gastric cancer is a significant global health concern due to its high morbidity and mortality. Gastric cancer-associated m...
promotes lactoferrin synthesis and secretion in bovine mammary epithelial cells through STAT3 and AP-1 transcription factor pathways
promotes lactoferrin synthesis and secretion in bovine mammary epithelial cells through STAT3 and AP-1 transcription factor pathways
Probiotics can support the immune function of dairy cows and contribute to the synthesis of milk components in mammary gla...
ALDH4A1 knockdown inhibits in vitro atherosclerosis model by modulating Trim28-mediated P53 ubiquitination to suppress ferroptosis of vascular endothelial cells
ALDH4A1 knockdown inhibits in vitro atherosclerosis model by modulating Trim28-mediated P53 ubiquitination to suppress ferroptosis of vascular endothelial cells
Atherosclerosis (AS) is a primary contributor to cardiovascular disease (CVD), resulting in high mortality. Ferroptosis, t...
ATF4 regulates PI3K/AKT signaling axis to promote angiogenesis after myocardial infarction
ATF4 regulates PI3K/AKT signaling axis to promote angiogenesis after myocardial infarction
Effective neovascularization is critical for tissue repair and the enhancement of cardiac function following myocardial in...
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