miR-3614-5p prevents endothelial differentiation and angiogenesis in human exfoliated deciduous teeth by targeting lysophosphatidic acid receptor 2

Ara H, Subedi U, Sharma P, Bhattarai S, Sharma S, Manikandan S, Yu X, Bhuiyan MS, Sun H, Miriyala S, Panchatcharam M (2022) Alteration of cellular energy metabolism through LPAR2-Axin2 axis in gastric cancer. Biomolecules. https://doi.org/10.3390/biom12121805

Article  PubMed  PubMed Central  Google Scholar 

Arderiu G, Civit-Urgell A, Díez-Caballero A, Moscatiello F, Ballesta C, Badimon L (2024) Differentiation of adipose tissue mesenchymal stem cells into endothelial cells depends on fat depot conditions: regulation by miRNA. Cells. https://doi.org/10.3390/cells13060513

Article  PubMed  PubMed Central  Google Scholar 

Feng Z, Ye Z, Xie J, Chen W, Li W, Xing C (2021) Study on the mechanism of LOXL1-AS1/miR-3614-5p/YY1 signal axis in the malignant phenotype regulation of hepatocellular carcinoma. Biol Direct 16:24

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gallant-Behm CL, Piper J, Dickinson BA, Dalby CM, Pestano LA, Jackson AL (2018) A synthetic microRNA-92a inhibitor (MRG-110) accelerates angiogenesis and wound healing in diabetic and nondiabetic wounds. Wound Repair Regen 26:311–323

Article  PubMed  Google Scholar 

Gao W, Yuan L, Zhang Y, Si Y, Wang X, Lv T, Wang YS (2023) miR-221/222 promote endothelial differentiation of adipose-derived stem cells by regulation of PTEN/PI3K/AKT/mTOR pathway. Appl Biochem Biotechnol 195:4196–4214

Article  CAS  PubMed  Google Scholar 

Gong T, Xu J, Heng B, Qiu S, Yi B, Han Y, Lo ECM, Zhang C (2019) EphrinB2/EphB4 signaling regulates DPSCs to induce sprouting angiogenesis of endothelial cells. J Dent Res 98:803–812

Article  CAS  PubMed  Google Scholar 

He T, Lu C, Gong W, Ge Z, Li R, Li X, Sun C, Li W, Long Q, Liu Q, Lai Y (2024) miRNA-27b-3p, let-7f-5p and miRNA-142-5p can be used in a novel serum diagnostic panel for clear cell renal cell carcinoma. Front Biosci (Landmark Ed) 29:186

Article  CAS  PubMed  Google Scholar 

Huang X, Liu Y, Li Z, Lerman LO (2023) Mesenchymal stem/stromal cells therapy for metabolic syndrome: potential clinical application? Stem Cells 41:893–906

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang Y (2017) Preclinical and clinical advances of GalNAc-decorated nucleic acid therapeutics. Mol Ther Nucleic Acids 6:116–132

Article  CAS  PubMed  Google Scholar 

Kang QM, Wang J, Chen SM, Song SR, Yu SC (2024) Glioma-associated mesenchymal stem cells. Brain 147:755–765

Article  PubMed  Google Scholar 

Kim M, Sur B, Villa T, Yun J, Nah SY, Oh S (2021) Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2. J Ginseng Res 45:575–582

Article  PubMed  PubMed Central  Google Scholar 

Kråkenes T, Wergeland S, Al-Sharabi N, Mohamed-Ahmed S, Fromreide S, Costea DE, Mustafa K, Bø L, Kvistad CE (2023) The neuroprotective potential of mesenchymal stem cells from bone marrow and human exfoliated deciduous teeth in a murine model of demyelination. PLoS ONE 18:e0293908

Article  PubMed  PubMed Central  Google Scholar 

Kunimatsu R, Nakajima K, Awada T, Tsuka Y, Abe T, Ando K, Hiraki T, Kimura A, Tanimoto K (2018) Comparative characterization of stem cells from human exfoliated deciduous teeth, dental pulp, and bone marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun 501:193–198

Article  CAS  PubMed  Google Scholar 

Li A, Sasaki JI, Abe GL, Katata C, Sakai H, Imazato S (2023) Vascularization of a bone organoid using dental pulp stem cells. Stem Cells Int 2023:5367887

Article  PubMed  PubMed Central  Google Scholar 

Li F, Yang H, Kong T, Chen S, Li P, Chen L, Cheng J, Cui G, Zhang G (2020) PGAM1, regulated by miR-3614-5p, functions as an oncogene by activating transforming growth factor-β (TGF-β) signaling in the progression of non-small cell lung carcinoma. Cell Death Dis 11:710

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li J, Zhu Y, Li N, Wu T, Zheng X, Heng BC, Zou D, Xu J (2021) Upregulation of ETV2 expression promotes endothelial differentiation of human dental pulp stem cells. Cell Transplant 30:963689720978739

Article  PubMed  PubMed Central  Google Scholar 

Liu W, Gong Q, Ling J, Zhang W, Liu Z, Quan J (2014) Role of miR-424 on angiogenic potential in human dental pulp cells. J Endod 40:76–82

Article  PubMed  Google Scholar 

Luo L, Xing Z, Liao X, Li Y, Luo Y, Ai Y, He Y, Ye Q (2022) Dental pulp stem cells-based therapy for the oviduct injury via immunomodulation and angiogenesis in vivo. Cell Prolif 55:e13293

Article  CAS  PubMed  PubMed Central  Google Scholar 

Luzuriaga J, Irurzun J, Irastorza I, Unda F, Ibarretxe G, Pineda JR (2020) Vasculogenesis from human dental pulp stem cells grown in matrigel with fully defined serum-free culture media. Biomedicines 8:483

Article  CAS  PubMed  PubMed Central  Google Scholar 

Neves VCM, Yianni V, Sharpe PT (2020) Macrophage modulation of dental pulp stem cell activity during tertiary dentinogenesis. Sci Rep 10:20216

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ning H, Tao H (2023) Small RNA sequencing of exosomal microRNAs reveals differential expression of microRNAs in preeclampsia. Medicine (Baltimore) 102:e35597

Article  CAS  PubMed  PubMed Central  Google Scholar 

Omi M, Hata M, Nakamura N, Miyabe M, Kobayashi Y, Kamiya H, Nakamura J, Ozawa S, Tanaka Y, Takebe J, Matsubara T, Naruse K (2016) Transplantation of dental pulp stem cells suppressed inflammation in sciatic nerves by promoting macrophage polarization towards anti-inflammation phenotypes and ameliorated diabetic polyneuropathy. J Diabetes Investig 7:485–496

Article  CAS  PubMed  Google Scholar 

Pritchard CC, Cheng HH, Tewari M (2012) MicroRNA profiling: approaches and considerations. Nat Rev Genet 13:358–369

Article  CAS  PubMed  PubMed Central  Google Scholar 

Samsonraj RM, Raghunath M, Nurcombe V, Hui JH, van Wijnen AJ, Cool SM (2017) Concise review: multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine. Stem Cells Transl Med 6:2173–2185

Article  PubMed  PubMed Central  Google Scholar 

Schwartz SL, Fischer JS, Kipnes MS, Boyle M (1987) Effects of short-term insulin therapy upon therapeutic response to glipizide. Am J Med 83:22–30

Article  CAS  PubMed  Google Scholar 

Staniowski T, Zawadzka-Knefel A, Skośkiewicz-Malinowska K (2021) Therapeutic potential of dental pulp stem cells according to different transplant types. Molecules. https://doi.org/10.3390/molecules26247423

Article  PubMed  PubMed Central  Google Scholar 

Sun LL, Li WD, Lei FR, Li XQ (2018) The regulatory role of microRNAs in angiogenesis-related diseases. J Cell Mol Med 22:4568–4587

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tsutsui TW (2020) Dental pulp stem cells: advances to applications. Stem Cells Cloning 13:33–42

PubMed  PubMed Central  Google Scholar 

Vuillier F, Li Z, Black I, Cruciani M, Rubino E, Michel F, Pellegrini S (2022) IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation. Front Immunol 13:939907

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang Y, Qi Z, Li Z, Bai S, Damirin A (2023) LPAR2-mediated action promotes human renal cell carcinoma via MAPK/NF-κB signaling to

Comments (0)

No login
gif