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Salivary pathobiont Klebsiella pneumoniae exacerbating periodontitis-related intestinal dyshomeostasis and accelerated metabolic syndrome
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Molecular sensitization patterns to mammalian allergens – possible impact on diagnostics and therapy
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The role of apolipoprotein C1 in mediating pyroptosis in Hashimoto’s thyroiditis via TLR10/MyD88/NF-κB pathway
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Immunorestorative effects of caraway and marjoram extracts on Th2-mediated inflammation in house dust mite–triggered asthma
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Wnt7a mediates the Wnt/β-catenin signaling pathway to influence ferroptosis in T lymphocytes of HIV-infected individuals
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Puerarin and DHEA combination therapy alleviates primary dysmenorrhea via inhibition of the Hsp90ab1/p38/JNK pathway
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NAT10 promotes lung cancer progression by enhancing glutamine metabolism through increasing ac4C modification on NIT2
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Siglec-15 promotes M2 polarization of Kupffer cells via DAP12/IRAK-M axis to alleviate acute rejection in liver transplantation
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Glutathione depletion activates cGAS-STING signaling via oxidative stress in preeclampsia
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Sinigrin inhibits PD-L1 expression via suppressing the JAK-STAT signaling pathway to modulate the tumor immune microenvironment in lung cancer
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Quercetin attenuates LTA-induced tight junction disruption in mammary epithelial cells by modulating autophagy via the AMPK/mTOR pathway
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Promoting keratinocyte psoriasiform changes and IL-17RE expression: Potential role of GLT1D1 in linear psoriasis
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PIAS1 attenuates the progression of abdominal aortic aneurysm by stabilizing PPARγ through SUMOylation
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Edwardsiella piscicida effector VgrG contributes to NCOA4-dependent ferritinophagy as a bacterial survival strategy in fish
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The CLEC-2–podoplanin axis inhibits dendritic cells migration and prolongs allograft survival in mice
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CSF1R signaling contributes to macrophage-associated CCL11 production and eosinophil recruitment in murine allergic conjunctivitis
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Biophysical characterization of zinc and DNA binding properties of MRN complex interacting protein
Studies in immortalized human mitotic cells demonstrated that MRN Complex Interacting Protein (MRNIP) plays a critical rol...
Structural features of collagens of warm-blooded and cold-blooded animals that determine differences in their thermal stability
We have previously shown that the thermal stability of animal collagens correlates with the number of hydrophobic amino ac...
Structure of the type VI secretion protein VgrS from Salmonella Typhimurium
Enteric bacterial pathogens employ various strategies to colonize the intestine and cause diseases ranging from gastroente...
Structural characterization of Meiothermus ruber LOV domain
Light Oxygen Voltage (LOV) domains, members of the Per/Arnt/Sim (PAS) family, are blue light-responsive photosensors found...
GNN2Pfam: Integrating protein sequence and structure with graph neural networks for Pfam domain annotation
Proteins are building blocks of life, playing many crucial roles within organisms, such as catalyzing chemical reactions, ...
Targeting Helicobacter pylori thymidylate kinase: structural insights and validation of novel inhibitors
Helicobacter pylori is a significant human pathogen, discovered by Warren and Marshall in 1982 (Ahmed, 2005). The human st...
“QuickStainer”: a rapid negative staining device for improved preservation of molecular structure
Volume 218, Issue 2, June 2026, 108299Author links open overlay panel, , , , , , , , Highlights•Negative staining is used ...
Comparative performance of structural aligners in functional domain annotation
Accurate protein domain annotation is essential for inferring protein function, and databases such as Pfam provide sequenc...