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Complement inhibitor therapy should be available to patients with paroxysmal nocturnal hemoglobinuria throughout the world
Complement inhibitor therapy should be available to patients with paroxysmal nocturnal hemoglobinuria throughout the world
The development of several complement-inhibiting medicines has been a major advance in the management of paroxysmal noctur...
Real-world effectiveness of fostamatinib in patients with immune thrombocytopenia: a single-center retrospective study
Real-world effectiveness of fostamatinib in patients with immune thrombocytopenia: a single-center retrospective study
Immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by increased platelet destruction and thromb...
Beyond nuclear export: chromatin-bound XPO1/CRM1 as a transcriptional scaffold
Beyond nuclear export: chromatin-bound XPO1/CRM1 as a transcriptional scaffold
XPO1/CRM1 (also known as Exportin-1) is best known as a RanGTP-dependent nuclear export receptor and has been explored as ...
Metabolic mimic of inherited bone marrow failure: LMBRD1 (cblF) deficiency in an infant
Metabolic mimic of inherited bone marrow failure: LMBRD1 (cblF) deficiency in an infant
Disorders of intracellular cobalamin metabolism are rare but treatable conditions that mimic bone marrow failure syndromes...
Dimensionality reduction enables MRD visualization in single-sample flow cytometric analysis in acute leukemia
Dimensionality reduction enables MRD visualization in single-sample flow cytometric analysis in acute leukemia
Minimal/measurable residual disease (MRD) analysis using multiparametric flow cytometry (MFC-MRD) is essential for therapy...
Timing of autologous stem cell transplantation and induction response in central nervous system lymphoma
Timing of autologous stem cell transplantation and induction response in central nervous system lymphoma
Primary and secondary central nervous system lymphomas (PCNSL and SCNSL, respectively) are aggressive non-Hodgkin lymphoma...
99mTc-HSA scintigraphy identifies protein-losing enteropathy in atypical GI-GVHD with modest diarrhea after allo-HSCT
99mTc-HSA scintigraphy identifies protein-losing enteropathy in atypical GI-GVHD with modest diarrhea after allo-HSCT
Protein-losing enteropathy (PLE) is an uncommon but clinically important manifestation of gastrointestinal graft-versus-ho...
Baseline plasma EBV-DNA load as an adjunctive biomarker for refractory or recurrent disease in pediatric EBV-HLH
Baseline plasma EBV-DNA load as an adjunctive biomarker for refractory or recurrent disease in pediatric EBV-HLH
Quantitative Epstein–Barr virus (EBV)-DNA measurement is used in EBV-associated hemophagocytic lymphohistiocytosis (...
Umbilical cord blood-derived CAR-NK cells: an emerging off-the-shelf platform for cancer immunotherapy
Umbilical cord blood-derived CAR-NK cells: an emerging off-the-shelf platform for cancer immunotherapy
Autologous CAR-T therapy has achieved notable success in B-cell malignancies, yet its broader application is constrained b...
Belumosudil for acute GVHD after allogeneic hematopoietic stem cell transplantation: a retrospective case series
Belumosudil for acute GVHD after allogeneic hematopoietic stem cell transplantation: a retrospective case series
Current therapies for acute graft-versus-host disease (aGVHD) are limited by suboptimal efficacy or excessive immunosuppre...
Association of carotid intima media thickness with cardiovascular disease risk in immune thrombocytopenia
Association of carotid intima media thickness with cardiovascular disease risk in immune thrombocytopenia
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by reduced platelet count, associated with both an i...
Road to treatment-free remission in chronic myeloid leukemia
Road to treatment-free remission in chronic myeloid leukemia
The development of BCR::ABL1 tyrosine kinase inhibitors (TKIs) has transformed chronic myeloid leukemia into a chronic dis...
Persistence of M-proteins detected by mass spectrometry
Kyle RA, Therneau TM, Rajkumar SV, Larson DR, Plevak MF, Offord JR, et al. Prevalence of monoclonal gammopathy of undeterm...
Lenalidomide and rituximab for relapsed/refractory follicular lymphoma: a systematic review and meta-analysis
Lenalidomide (len) and rituximab (R2) is standard second-line therapy for follicular lymphoma (FL), and the backbone and c...
Immune effector cell associated hematotoxicity (ICAHT) with BCMA CAR T cell therapy in the earlier lines
B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapy is highly effective in relapsed/r...
Clinicomolecular features and clonal evolution of KMT2A-PTD AML: prognostic impact of concurrent FLT3-ITD under 2022 ELN risk stratification
Clinicomolecular features and clonal evolution of KMT2A-PTD AML: prognostic impact of concurrent FLT3-ITD under 2022 ELN risk stratification
Several limitations should be acknowledged. This was a retrospective single-center study conducted across multiple treatme...
Infection burden among patients with triple-class–exposed RRMM receiving non–T-cell–redirecting therapies: a US claims study
Triple-class–exposed (TCE) relapsed/refractory multiple myeloma (RRMM) is associated with cumulative immunosuppressi...
Correction: Safety and efficacy of ciltacabtagene autoleucel for relapsed/refractory multiple myeloma: a CIBMTR study
These authors contributed equally: Doris K. Hansen, Danai Dima, Hira Mian.These authors jointly supervised this work: Surb...