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From generation to validation: Deep generative models for antimicrobial peptide discovery
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Genetic code expansion: Bridging synthetic biology precision and cellular complexity to decipher molecular mechanisms of diseases
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Synthetic DNA circuits for programming cell functions
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Defining the rules of biocompatible chemistry
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Controlling distance, time and reactivity: Chemical principles of proximity labeling
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Medical isotope-labeled nucleic acids: A decade of progress toward theranostics (2015–2025)
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Discovery and engineering of polymerases and ligases for the synthesis of modified nucleic acids
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Proximity labeling tools for studying chromatin interactomes
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Advances in proximity labeling strategies for interactome mapping and functional interrogation
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Recent advances in spatial proteomics by super-resolution proximity labeling
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Light-driven spatial proteomics: Photocatalytic strategies for mapping protein microenvironments
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Proximity chemistries to study RNA biology at the subcellular scale
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Prediction of protein–protein interactions and co-complex models with deep learning
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Imaging genome dynamics in real time with CRISPR-based technologies
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High-resolution molecular mapping by expansion-coupled label-free and multimodal imaging
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Chemigenetic fluorescent biosensors in biological imaging - New trends and advances
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Towards better red emitters for bioimaging: Innovations in rhodamine and cyanine chemistry
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Therapeutic potential and resistance of proline-rich antimicrobial peptides
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Self-resistance as a guide to discovering bioactive natural products
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Recent advances in glycoconjugate-based therapeutics
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How ligands tune the parathyroid hormone receptor’s grip on β-arrestin
How ligands tune the parathyroid hormone receptor’s grip on β-arrestin
β-arrestins are known modulators of GPCR signaling, but their precise interaction with class B GPCRs is poorly unders...
Rap1-mediated steric hindrance protects telomeres from MRX sensing
Rap1-mediated steric hindrance protects telomeres from MRX sensing
Telomere capping largely depends on telomere length. Abnormally short telomeres are prone to activate DNA damage checkpoin...
Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny
Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny
At the onset of reproduction, oviparous animals synthesize large amounts of yolk in somatic tissues to provide lipids and ...
Dynamic regulation of H3K9 dimethylation drives mouse minor zygotic genome activation
Dynamic regulation of H3K9 dimethylation drives mouse minor zygotic genome activation
Minor zygotic genome activation (ZGA) is crucial for early development and totipotency acquisition; however, the regulator...
Yolk transports miRNAs to embryos and enhances progeny stress resilience
Yolk transports miRNAs to embryos and enhances progeny stress resilience
This study shows that yolk, a conserved vehicle for nutrient provisioning to developing eggs, also transports regulatory s...
Distinct repair outcomes from single and convergent replication fork collapse
Distinct repair outcomes from single and convergent replication fork collapse
Replication fork collapse at single-strand DNA breaks threatens genome stability but how such forks are repaired and resol...
How cohesin guides DNA repair via scanning and tethering
How cohesin guides DNA repair via scanning and tethering
A broken chromosome must find an identical DNA sequence among billions of bases packed into the nucleus. Although homologo...
Sex differences in coordination of center of mass kinematics during table tennis footwork
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The effect of interposition arthroplasty on the contact mechanics of the elbow joint
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