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From generation to validation: Deep generative models for antimicrobial peptide discovery

Genetic code expansion: Bridging synthetic biology precision and cellular complexity to decipher molecular mechanisms of diseases

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Synthetic DNA circuits for programming cell functions

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Defining the rules of biocompatible chemistry

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Controlling distance, time and reactivity: Chemical principles of proximity labeling

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Medical isotope-labeled nucleic acids: A decade of progress toward theranostics (2015–2025)

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Discovery and engineering of polymerases and ligases for the synthesis of modified nucleic acids

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Proximity labeling tools for studying chromatin interactomes

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Advances in proximity labeling strategies for interactome mapping and functional interrogation

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Recent advances in spatial proteomics by super-resolution proximity labeling

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Light-driven spatial proteomics: Photocatalytic strategies for mapping protein microenvironments

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Proximity chemistries to study RNA biology at the subcellular scale

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Prediction of protein–protein interactions and co-complex models with deep learning

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Imaging genome dynamics in real time with CRISPR-based technologies

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High-resolution molecular mapping by expansion-coupled label-free and multimodal imaging

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Chemigenetic fluorescent biosensors in biological imaging - New trends and advances

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Towards better red emitters for bioimaging: Innovations in rhodamine and cyanine chemistry

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Therapeutic potential and resistance of proline-rich antimicrobial peptides

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Self-resistance as a guide to discovering bioactive natural products

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Recent advances in glycoconjugate-based therapeutics

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Mass spectrometry-based characterization of histone post-translational modification

In eukaryotes, the fundamental unit of chromatin is nucleosome, which contains approximately 147 base pairs of DNA wrapped...

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Evolving advances of proximity labeling in capturing biomolecular interactions

Proximity labeling (PL) has emerged as a powerful technology to capture biomolecular interactions in living systems, gaini...

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In vivo cross-linking mass spectrometry: Advances and challenges in decoding protein conformational dynamics and complex regulatory networks in living cells

The dynamic conformations of intracellular proteins and their interaction networks constitute the structural foundation of...

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Emerging trends in chemoproteomics: Mapping the landscape of protein–metabolite interactions

Metabolites, long recognized as essential reactants and products of cellular metabolism—serving as energy carriers, struct...

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Optogenetic engineering for ion channel modulation

The field of optogenetics traces its roots to the discovery of bacteriorhodopsin (BR) from Halobacterium salinarum in 1971...

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Lipid probes to study ion channels

Over 1000 different lipid species are found in eucaryotic cells with 5 % of our genes solely used for their synthesis [1]....

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Stimuli-responsive synthetic ionophores for therapeutic applications

The translocation of ions across the cellular membrane is essential for adequate regulation of different physiological pro...

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Illuminating antifungal mode of action and resistance with fluorescent probes

The rise in fungal infections, driven by pathogens resistant to the limited scope of antifungal agents available, poses an...

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Recent advances in high-throughput screening methods for small molecule modulators in bacteria

It is estimated that antibiotic-resistant (ABR) infections directly caused 1.27 million deaths and contributed to a furthe...

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Corrigendum to “Enabling structural biological electron paramagnetic resonance spectroscopy in membrane proteins through spin labelling” Curr Opin Chem Biol 84 (2025) 102564

Volume 85, April 2025, 102583Author links open overlay panelAnokhi Shah 1 2, Joshua L. Wort 1 2, Yue Ma 1 2, Christos Plio...

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