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The prognostic impact of pregnancy-associated melanoma on overall and melanoma-specific survival: A systematic review and meta-analysis

Critical Reviews In Oncology Hematology

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First-line immunotherapy with or without PARP inhibitors in advanced ovarian cancer: A meta-analysis including bevacizumab use, molecular status, and PD-L1 expression

Critical Reviews In Oncology Hematology

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PCSK9 in the liver metastatic niche: From cholesterol homeostasis to tumor microenvironment reprogramming

Critical Reviews In Oncology Hematology

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Mitophagy in lymph node metastasis: Mechanisms, immune consequences and therapeutic opportunities

Critical Reviews In Oncology Hematology

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Dendritic cell-driven immune rebalancing as a systemic regulator of tumor and neurodegenerative microenvironments

Critical Reviews In Oncology Hematology

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Overcoming immunotherapy resistance in extensive-stage small cell lung cancer: Insights into mechanisms and therapeutic opportunities

Critical Reviews In Oncology Hematology

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Harnessing myeloid plasticity in CAR macrophages for solid tumor immunotherapy

Critical Reviews In Oncology Hematology

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Bile acids in the tumor immune microenvironment of hepatocellular carcinoma: Mechanisms of immunotherapy resistance and therapeutic opportunities

Critical Reviews In Oncology Hematology

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Hybrid membrane nanosystems for cancer immunotherapy: Biomimetic design, immune activation, and translational potential

Critical Reviews In Oncology Hematology

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Neoadjuvant immunotherapy in locally advanced head and neck squamous cell carcinoma: From oncologic outcomes to response-adaptive treatment de-escalation

Critical Reviews In Oncology Hematology

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Immune checkpoint inhibitor resistance in non-small cell lung cancer: An updated view through the cancer-immunity cycle

Critical Reviews In Oncology Hematology

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Macrophages in colorectal cancer: Origin, function and significance of targeted therapy

Critical Reviews In Oncology Hematology

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Translational aspects of Desmoplastic small round cell tumor (DSRCT): An expert consensus paper from the OCTOPUS group

Critical Reviews In Oncology Hematology

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Molecular understanding and clinical aspects of adoptive cellular immunotherapy in prostate cancer

Critical Reviews In Oncology Hematology

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From bone alterations to tumours: Genetic drivers linking Paget’s disease of bone to cancer

Critical Reviews In Oncology Hematology

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Title: Role of O6-methylguanine DNA methyltransferase status as predictive factor for alkylatin-based chemotherapy in advanced neuroendocrine tumors: State of the art

Critical Reviews In Oncology Hematology

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Targeting KRAS G12C in non-small cell lung cancer: Breakthrough inhibitors and combination approaches

Critical Reviews In Oncology Hematology

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Gut microbiome dysbiosis and cancer: A systematic review on the emerging role of probiotics in oncology

Critical Reviews In Oncology Hematology

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Brain tumor susceptibility: From genetic predisposition syndromes to extended characterization of genomic determinants

Critical Reviews In Oncology Hematology

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Research advances in dual-conversion therapy for hepatocellular carcinoma

Critical Reviews In Oncology Hematology

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The influence of genetic variation on late effects in childhood cancer survivors: An updated systematic review

Over the past decades, childhood cancer survival rates have increased significantly due to an enhanced understanding of ca...

Critical Reviews In Oncology Hematology

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Individual radiosensitivity testing in 2025: Current advances and future directions for personalized radiotherapy

Radiation therapy (RT) is a cornerstone of modern oncology, with approximately 60 % of cancer patients receiving RT during...

Critical Reviews In Oncology Hematology

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Gut microbiota and chemoradiotherapy response in rectal cancer: Biomarker opportunities

Christophe Taoum, MD, PhD. Surgical oncologist at the Montpellier Cancer Institute (ICM), France. PhD in collaboration wit...

Critical Reviews In Oncology Hematology

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Molecular landscape of colorectal cancer liver metastasis: Tumor microenvironment heterogeneity and driver inference

Colorectal cancer is one of the most common malignancies worldwide. As of 2024, the incidence and mortality rates of CRC c...

Critical Reviews In Oncology Hematology

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Decoding optic pathway gliomas: Molecular insights and emerging therapies

Shepeng Wei is the chief of the Department of Neurosurgery at Shidong Hospital, Shanghai, China, where he also serves as c...

Critical Reviews In Oncology Hematology

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Biomarkers in blood and saliva to screen fragile patients with solid tumors: A systematic review of the literature

Univ. Prof. Dr. med. Annette Hasenburg, MD, Director of the Clinic and Polyclinic for Obstetrics and Women's Health, exper...

Critical Reviews In Oncology Hematology

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Immune evasion in endometrial cancer: Unraveling the latest mechanisms and future directions

Endometrial cancer (EC) is the third most common malignancy in women worldwide, with an estimated 420,000 new cases diagno...

Critical Reviews In Oncology Hematology

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Dynamic interplay of neuroendocrine signaling and immuno-surveillance in tumor niche remodeling

The nervous system has a dual role in regulating the immune system. It detects and processes stimuli and directly influenc...

Critical Reviews In Oncology Hematology

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Impact of exercise in patients with pancreatic cancer across different treatment phases: A systematic review

Salvatore Paiella, MD, Ph.D, Associate Professor at the General and Pancreatic Surgery Unit of the Pancreas Institute of t...

Critical Reviews In Oncology Hematology

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Tenosynovial giant cell tumor (TGCT): Mechanisms and advances in targeted treatments

Volume 216, December 2025, 104951Author links open overlay panel, , , , Highlights•TGCT in the joints and tendon sheaths n...

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