SCI Abstract

search
+
A three-component 1,3-dipolar cycloaddition of pyrazolone derived azomethine ylides with succinimides for the construction of novel spiro-pyrazolone-pyrrolizines containing succinimides
A three-component 1, 3-dipolar cycloaddition of maleimides with azomethine ylides generated in situ from pyrazolones and p...
Modular synthesis of sulfilimines via NFSI-mediated S-arylation of sulfenamides with naphthols, phenols and indoles †
Sulfilimines were exploited as valuable moieties in organic synthesis and medicinal chemistry, however, efficient methods ...
A Hexadentate Co(III) Catalyst Enables One-Pot Quinazolinone Synthesis via Metal–Ligand Cooperative Alcohol Activation
Here, we present the first Co(III) catalysed efficient metal ligand cooperative route for the synthesis of quinazolinone u...
Electrochemical Synthesis of 2-Substituted Quinazolinones from Primary Benzylic C(sp3)–H bonds and 2-Aminobenzamides
An electrochemical promoted primary benzylic C(sp3)–H directive dehydrogenative cascade cyclization for the synthesis of q...
Electrochemical C-H Trifluoromethylation of 4-Phenylthiazol-2amines
Herein, we report a new methodology for the electrochemical oxidative C–H trifluoromethylation of 4-phenylthiazol-2-amines...
Radical Cascade Cyclization of 3-Allyl-2-arylquinazolinones Mediated by Silver(I) Salts to Access SCF₃/SCN-Enriched Dihydroisoquinolino[1,2-b]quinazolinones
Herein, we describe an efficient approach for the synthesis of SCF₃-and SCN-functionalized polycyclic Dihydroisoquinolino[...
Nickel catalysed SET-induced oxygenation of (aryl)(Nheteroaryl)methanes with molecular oxygen
The nickel catalyzed C–H oxygenation is a fundamentally impotant, but much less studied transformation. Herein, we report ...
Connecting the Mechanistic Steps of Cyclic Dipeptide Formation by Proton-Transfer Network: pH, Temperature, Pressure, and Nuclear Quantum Effects
We expanded our previous mapping of peptide condensation reaction mechanism from the linear dipeptide formation to the cyc...
Sodium alginate-modified copper catalytic membrane for carbene N-H insertion
A novel copper-based catalytic membrane (Cu@SA-CM) was fabricated via surface cross-linking using sodium alginate as a gre...
Enantioselective Michael additions promoted by a bifunctional charge-activated thiourea catalyst
A new bifunctional thiourea featuring a methylated pyridinium ion and a chiral amine is reported. This readily prepared or...
Copper-Catalyzed Four-Component Radical Cascade Cyclization of Enynes to Assemble Trifluoromethyl-and Carbamoyloxyl-su bstituted Pyrrolo[1,2-a]benzimidazoles
A copper-catalyzed multicomponent radical domino reaction of 1-allyl-2-ethynylbenzoimidazoles with Togni's reagent, am...
Molecular Interactions of Cinnamil and Quinoxaline Derivatives by Bcl-2 Antiapoptotic Proteins: A Computational Study
Antiapoptotic proteins represent a major obstacle to the success of anticancer therapies, as they promote the survival of ...
Chemoselective Enzymatic Acylation of Glycine as a Green Route to N-Acyl aminoacid Surfactants
Population and industrial growth are driving demand for surfactants, as they are widely used in various areas of human act...
Photoredox radical annulation of aroyl sulfoxonium ylides and alkynes for 1-naphthol assembly
The [4+2] cycloaddition of sulfoxonium ylides with alkynes provides direct access to valuable 1-naphthol derivatives. To o...
Zinc-catalyzed dehydrogenative coupling of primary alcohols and secondary/benzyl phosphine oxides for alkenes synthesis
A zinc-catalyzed method for the direct conversion of primary alcohols into alkenes under acceptorless dehydrogenation cond...
Enantioselective copper (II) catalysed (4+1) cycloaddition of aza-oquinone methides and bromomalonates. Facile access to enantioenriched indolines
Optically active indolines are a valuable structural motif present in numerous naturally occurring and biologically active...
Synthesis of 2-Furanyl Quinolines via Zinc-Catalyzed Cascade Cyclization of Enynones with Anthranils
A facile Zinc(II)-catalyzed cascade cyclization of enynones with anthranils was developed to afford a series of 2-furanyl ...
Molybdenum-Catalyzed Deoxygenative Heterocyclization of 2-Nitroazobenzenes: A Novel Strategy for Catalytic Synthesis of 2-Aryl-2H-benzo[d][1,2,3]triazoles
A novel strategy for catalytic synthesis of 2-aryl-2H-benzo[d][1,2,3]triazoles by non-noble molybdenum-catalyzed deoxygena...
Non-enzymatic Synthesis of C-Methylated Fluostatins: Discovery and Reaction Mechanism
Two methylation FSTs, FST B3/FST B4 (1/2), were obtained from oxidative ring-opening reaction. The structure of 1/2 were e...
Oxidative cascade cyclization of N-arylacrylamides with TMSN3
An azido-radical-triggered cyclization of N-(o-cyanobiaryl)acrylamides with TMSN3 via a C(sp3)–N/C(sp2)–C(sp3)/C(sp2)–N bo...
Highly effective and selective FeBr3-promoted deuterium bromination/cyclization of 1,n-enynes
A highly effective and selective FeBr3 promoted deuterium bromination/cyclization of 1,n-enynes is reported. On one hand, ...
Practical and scalable enantioselective synthesis of (+)-majoranolide from Cyrene
A two-step enantioselective gram scale synthesis of the Persea derived γ-lactones (+)-majoranolide and (+)-majoranolide B ...
A transition-metal-free azide-alkyne cycloaddition / hydroamination cascade reaction for the construction of triazole-fused piperazin-2-ones
A time-dependent, divergent synthesis of highly functionalized [1,2,3]triazolo[1,5-a]pyrazin-4(5H)-one (reaction time: 12 ...
Visible-light-induced decarboxylative cascade cyclization of acryloylbenzamides with N-hydroxyphthalimide esters via EDA complexes
Visible-light-induced decarboxylative cascade reactions of acryloylbenzamides with alkyl N-hydroxyphthalimide (NHP) esters...
Isocyanide-based multicomponent reactions for the synthesis of benzopyran derivatives with biological scaffolds
Benzopyrans (BZPs) are one of the most privileged and influential small O-heterocycles that form the core of many natural ...
Iridium (III)-Catalyzed β-Trifluoromethyl Enone Carbonyl Directed Regio-Selective C(sp2)-H Olefination
Due to the lower LUMO energy level at β-position of α,β-unsaturated-β-trifluoromethyl enone than its non-fluorinated count...
Selective α-oxidation of amides via visible-light-driven Iron-catalysis
The hydroxyl radical (•OH) as one of the highly reactive species can react unselectively with a wide range of chemicals. T...
Direct Synthesis of Phenanthrenyl Triflates from 1-Biphenylyl-2-diazo-2-aryl Ketones and Triflic Anhydride
A strategy for direct synthesis of phenanthrenyl triflates from 1-biphenylyl-2-diazo-2-aryl ketones and triflic anhydride ...
Synthesis of 4-Sulfonyl-1,7-diesters via K2CO3-Mediated Alkylative Debenzoylation of α-Sulfonyl o-Hydroxyacetophenones with Acrylates
The synthesis of 4-sulfonyl-1,7-diesters was well-developed, under the open-vessel condition, by K2CO3-mediated double alk...
Brønsted Acid and Ni(II)-catalyzed C-H Oxidation/Rearrangement of Cyclotriveratrylenes (CTVs) to Cyclic and Acyclic Quinones as Potential Anti-cancer Agents
This paper describes a simple and practical protocol for the direct synthesis of acyclic and cyclic quinone derivatives vi...
Load More
format_indent_increase