Andreou AZ and Klostermeier D 2013 The DEAD-box helicase eIF4A: paradigm or the odd one out? RNA Biol. 10 19–32

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blum S, Schmid SR, Pause A, et al. 1992 ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 89 7664–7668

Article  CAS  PubMed  PubMed Central  Google Scholar 

Conroy SC, Dever TE, Owens CL, et al. 1990 Characterization of the 46,000-dalton subunit of eIF-4F. Arch. Biochem. Biophys. 282 363–371

Article  CAS  PubMed  Google Scholar 

Das S 2021 Taking a re-look at cap-binding signatures of the mRNA cap-binding protein eIF4E orthologues in trypanosomatids. Mol. Cell. Biochem. 476 1037–1049

Article  CAS  PubMed  Google Scholar 

Das S 2022 Analysis of domain organization and functional signatures of trypanosomatid keIF4Gs. Mol. Cell. Biochem. 477 2415–2431

Article  CAS  PubMed  Google Scholar 

Dhalia R, Reis CR, Freire ER, et al. 2005 Translation initiation in Leishmania major: characterisation of multiple eIF4F subunit homologues. Mol. Biochem. Parasitol. 140 23–41

Article  CAS  PubMed  Google Scholar 

Dhalia R, Marinsek N, Reis CR, et al. 2006 The two eIF4A helicases in Trypanosoma brucei are functionally distinct. Nucleic Acids Res. 34 2495–2507

Article  CAS  PubMed  PubMed Central  Google Scholar 

Eswar N, Webb B, Marti-Renom MA, et al. 2006 Comparative protein structure modeling using Modeller. Curr. Protoc. Bioinformatics 5 5–6

Google Scholar 

Feoktistova K, Tuvshintogs E, Do A, et al. 2013 Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity. Proc. Natl. Acad. Sci. USA 110 13339–13344

Article  CAS  PubMed  PubMed Central  Google Scholar 

Freire ER, Dhalia R, Moura DM, et al. 2011 The four trypanosomatid eIF4E homologues fall into two separate groups, with distinct features in primary sequence and biological properties. Mol. Biochem. Parasitol. 176 25–36

Article  CAS  PubMed  Google Scholar 

Freire ER, Vashisht AA, Malvezzi AM, et al. 2014 eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma brucei. RNA 20 1272–1286

Article  CAS  PubMed  PubMed Central  Google Scholar 

Freire ER, Sturm NR, Campbell DA, et al. 2017 The role of cytoplasmic mRNA cap-binding protein complexes in Trypanosoma brucei and other trypanosomatids. Pathogens 6 55

Article  PubMed  PubMed Central  Google Scholar 

Galicia-Vazquez G, Cencic R, Robert F, et al. 2012 A cellular response linking eIF4AI activity to eIF4AII transcription. RNA 18 1373–1384

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gingras AC, Raught B and Sonenberg N 2001 Regulation of translation initiation by FRAP/mTOR. Genes Dev. 15 807–826

Article  CAS  PubMed  Google Scholar 

Ho CK and Shuman S 2001 A yeast-like mRNA capping apparatus in Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 98 3050–3055

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ignatochkina AV, Takagi Y, Liu Y, et al. 2015 The messenger RNA decapping and recapping pathway in Trypanosoma. Proc. Natl. Acad. Sci. USA 112 6967–6972

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jackson RJ, Hellen CU and Pestova TV 2010 The mechanism of eukaryotic translation initiation and principles of its regulation. Nat. Rev. Mol. Cell Biol. 11 113–127

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jumper J, Evans R, Pritzel A, et al. 2021 Highly accurate protein structure prediction with AlphaFold. Nature 596 583–589

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liang L, Diehl-Jones W and Lasko P 1994 Localization of vasa protein to the Drosophila pole plasm is independent of its RNA-binding and helicase activities. Development 120 1201–1211

Article  CAS  PubMed  Google Scholar 

Lu WT, Wilczynska A, Smith E, et al. 2014 The diverse roles of the eIF4A family: you are the company you keep. Biochem. Soc. Trans. 42 166–172

Article  CAS  PubMed  Google Scholar 

Marintchev A 2013 Roles of helicases in translation initiation: a mechanistic view. Biochim. Biophys. Acta 1829 799–809

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marintchev A, Edmonds KA, Marintcheva B, et al. 2009 Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation. Cell 136 447–460

Article  CAS  PubMed  PubMed Central  Google Scholar 

Meijer HA, Kong YW, Lu WT, et al. 2013 Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation. Science 340 82–85

Article  CAS  PubMed  Google Scholar 

Moura DM, Reis CR, Xavier CC, et al. 2015 Two related trypanosomatid eIF4G homologues have functional differences compatible with distinct roles during translation initiation. RNA Biol. 12 305–319

Article  PubMed  PubMed Central  Google Scholar 

Oberer M, Marintchev A and Wagner G 2005 Structural basis for the enhancement of eIF4A helicase activity by eIF4G. Genes Dev. 19 2212–2223

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pause A and Sonenberg N 1992 Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A. EMBO J. 11 2643–2654

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pause A, Methot N and Sonenberg N 1993 The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis. Mol. Cell. Biol. 13 6789–6798

CAS  PubMed  PubMed Central  Google Scholar 

Pettersen EF, Goddard TD, Huang CC, et al. 2004 UCSF Chimera–a visualization system for exploratory research and analysis. J. Comput. Chem. 25 1605–1612

Article  CAS  PubMed  Google Scholar 

Pradhan A and Tuteja R 2007 Bipolar, dual Plasmodium falciparum helicase 45 expressed in the intraerythrocytic developmental cycle is required for parasite growth. J. Mol. Biol. 373 268–281

Article  CAS  PubMed  Google Scholar 

Rogers GW, Richter NJ and Merrick WC 1999 Biochemical and kinetic characterization of the RNA helicase activity of eukaryotic initiation factor 4A. J. Biol. Chem. 274 12236–12244

Article  CAS  PubMed  Google Scholar 

Rozen F, Pelletier J, Trachsel H, et al. 1989 A lysine substitution in the ATP-binding site of eucaryotic initiation factor 4A abrogates nucleotide-binding activity. Mol. Cell. Biol. 9 4061–4063

CAS  PubMed  PubMed Central  Google Scholar 

Schmid SR and Linder P 1991 Translation initiation factor 4A from Saccharomyces cerevisiae: analysis of residues conserved in the D-E-A-D family of RNA helicases. Mol. Cell. Biol. 11 3463–3471

CAS  PubMed  PubMed Central  Google Scholar 

Schutz P, Bumann M, Oberholzer AE, et al. 2008 Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein–protein interactions. Proc. Natl. Acad. Sci. USA 105 9564–9569

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sengoku T, Nureki O, Nakamura A, et al. 2006 Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell 125 287–300

Article  CAS  PubMed  Google Scholar 

Sokabe M and Fraser CS 2017 A helicase-independent activity of eIF4A in promoting mRNA recruitment to the human ribosome. Proc. Natl. Acad. Sci. USA 114 6304–6309

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stuart K, Brun R, Croft S, et al. 2008 Kinetoplastids: related protozoan pathogens, different diseases. J. Clin. Invest. 118 1301–1310

Article  CAS  PubMed