Saddle pulmonary embolism: results of a series of patients undergoing pharmaco-mechanical thrombolysis

Konstantinides SV, Meyer G, Becattini C et al (2019) 2019 ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J 41:543–603

Article  Google Scholar 

Raskob GE, Angchaisuksiri P, Blanco AN et al (2014) Thrombosis: a major contributor to global disease burden. Arterioscler Thromb Vasc Biol 34:2363–2371

Article  CAS  PubMed  Google Scholar 

Ata F, Ibrahim WH, Choudry H et al (2022) Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: a systematic review and meta-analysis. Thromb Res 217:86–95

Article  CAS  PubMed  Google Scholar 

Belohlavek J, Dytrych V, Linhart A (2013) Pulmonary embolism, part I: Epidemiology, risk factors and risk stratification, pathophysiology, clinical presentation, diagnosis and nonthrombotic pulmonary embolism. Exp Clin Cardiol 18:129–138

PubMed  PubMed Central  Google Scholar 

Dogan H, de Roos A, Geleijins J, Huisman MV, Kroft LJ (2015) The role of computed tomography in the diagnosis of acute and chronic pulmonary embolism. Diagn Interv Radiol 21:307–316

Article  PubMed  PubMed Central  Google Scholar 

Ryu JH, Pellikka PA, Froehling DA, Peters SG, Aughenbaugh GL (2007) Saddle pulmonary embolism diagnosed by CT angiography: frequency, clinical features and outcome. Respir Med 101:1537–1542

Article  PubMed  Google Scholar 

Gandara E, Bose G, Erkens P, Rodgers M, Carrier M, Wells P (2011) Outcomes of saddle pulmonary embolism: a nested case-control study. J Thromb Haemost 9:867–869

Article  CAS  PubMed  Google Scholar 

Sardi A, Gluskin J, Guttentag A, Kotler MN, Braitman LE, Lippmann M (2011) Saddle pulmonary embolism: is it as bad as it looks? A community hospital experience. Crit Care Med 39:2413–2418

Article  PubMed  Google Scholar 

Pruszczyk P, Pacho R, Ciurzynski M et al (2003) Short term clinical outcome of acute saddle pulmonary embolism. Heart 89:335–336

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kucher N, Goldhaber SZ (2005) Management of massive pulmonary embolism. Circulation 112:e28-32

Article  PubMed  Google Scholar 

Cueto-Robledo G, Roldan-Valadez E, Guerrero-Velazquez JF et al (2023) Acute pulmonary embolism code and rapid response teams are necessary: a review of Global and Mexico’s Teams (MGH PERT). Curr Probl Cardiol 48:101462

Article  PubMed  Google Scholar 

Qanadli SD, El Hajjam M, Vieillard-Baron A et al (2001) New CT index to quantify arterial obstruction in pulmonary embolism: comparison with angiographic index and echocardiography. AJR Am J Roentgenol 176:1415–1420

Article  CAS  PubMed  Google Scholar 

Ismayl M, Ismayl A, Hamadi D, Aboeata A, Goldsweig AM (2024) Catheter-directed thrombolysis versus thrombectomy for submassive and massive pulmonary embolism: a systematic review and meta-analysis. Cardiovasc Revasc Med 60:43–52

Article  PubMed  Google Scholar 

Schultz J, Andersen A, Kabrhel C, Nielsen-Kudsk JE (2018) Catheter-based therapies in acute pulmonary embolism. EuroIntervention 13:1721–1727

Article  PubMed  Google Scholar 

Isath A, Shah R, Bandyopadhyay D et al (2023) Dispelling the saddle pulmonary embolism myth (from a Comparison of Saddle Versus Non-Saddle Pulmonary Embolism). Am J Cardiol 201:341–348

Article  PubMed  Google Scholar 

Victory Srinivasan N, Maldonado JE, Melek A, Haddad FM, Patel AA (2022) Outcomes of surgical and mechanical thrombectomy in massive saddle pulmonary embolism: a national perspective. Cureus 14:e29885

PubMed  PubMed Central  Google Scholar 

Alkinj B, Pannu BS, Apala DR, Kotecha A, Kashyap R, Iyer VN (2017) Saddle vs nonsaddle pulmonary embolism: clinical presentation, hemodynamics, management, and outcomes. Mayo Clin Proc 92:1511–1518

Article  PubMed  Google Scholar 

Choi KJ, Cha SI, Shin KM et al (2014) Central emboli rather than saddle emboli predict adverse outcomes in patients with acute pulmonary embolism. Thromb Res 134:991–996

Article  CAS  PubMed  Google Scholar 

Morgenthaler TI, Ryu JH (1995) Clinical characteristics of fatal pulmonary embolism in a referral hospital. Mayo Clin Proc 70:417–424

Article  CAS  PubMed  Google Scholar 

Musani MH (2011) Asymptomatic saddle pulmonary embolism: case report and literature review. Clin Appl Thromb Hemost 17:337–339

Article  PubMed  Google Scholar 

Wong KJ, Kushnir M, Billett HH (2021) Saddle pulmonary embolism: demographics, clinical presentation, and outcomes. Crit Care Explor 3:e0437

Article  PubMed  PubMed Central  Google Scholar 

Araoz PA, Gotway MB, Trowbridge RL et al (2003) Helical CT pulmonary angiography predictors of in-hospital morbidity and mortality in patients with acute pulmonary embolism. J Thorac Imaging 18:207–216

Article  PubMed  Google Scholar 

Ghuysen A, Ghaye B, Willems V et al (2005) Computed tomographic pulmonary angiography and prognostic significance in patients with acute pulmonary embolism. Thorax 60:956–961

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu M, Miao R, Guo X et al (2017) Saddle pulmonary embolism: laboratory and computed tomographic pulmonary angiographic findings to predict short-term mortality. Heart Lung Circ 26:134–142

Article  PubMed  Google Scholar 

Meneveau N, Seronde MF, Blonde MC et al (2006) Management of unsuccessful thrombolysis in acute massive pulmonary embolism. Chest 129:1043–1050

Article  PubMed  Google Scholar 

Cueto-Robledo G, Rivera-Sotelo N, Roldan-Valadez E et al (2022) A brief review on failed hybrid treatment for massive pulmonary embolism: catheter-directed thrombolysis (CDT) and pharmaco-mechanical thrombolysis (PMT). Curr Probl Cardiol 47:101294

Article  PubMed  PubMed Central  Google Scholar 

Pruszczyk P, Klok FA, Kucher N et al (2022) Percutaneous treatment options for acute pulmonary embolism: a clinical consensus statement by the ESC Working Group on Pulmonary Circulation and Right Ventricular Function and the European Association of Percutaneous Cardiovascular Interventions. EuroIntervention 18:e623–e638

Article  PubMed  PubMed Central  Google Scholar 

Callese TE, Moriarty JM, Maehara C et al (2023) Cost drivers in endovascular pulmonary embolism interventions. Clin Radiol 78:e143–e149

Article  CAS  PubMed  Google Scholar 

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