Systematic review and network meta-analysis of cryptoglandular complex anal fistula treatment: evaluation of surgical strategies

Steele SR, Kumar R, Feingold DL, Rafferty JL, Buie WD (2011) Practice parameters for the management of perianal abscess and fistula-in-ano. Dis Colon Rectum 54(12):1465–1474. https://doi.org/10.1097/DCR.0b013e31823122b3

Article  PubMed  Google Scholar 

Garg P, Sodhi SS, Garg N (2020) Management of complex cryptoglandular anal fistula: challenges and solutions. Clin Exp Gastroenterol 13:555–567. https://doi.org/10.2147/CEG.S198796

Article  CAS  PubMed  PubMed Central  Google Scholar 

Limura E, Giordano P (2015) Modern management of anal fistula. World J Gastroenterol 21(1):12–20. https://doi.org/10.3748/wjg.v21.i1.12

Article  PubMed  PubMed Central  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, et al. (2021) The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. The BMJ;372. https://doi.org/10.1136/bmj.n71

Hutton B, Catalá-López F, Moher D (2016) La extensión de la declaración PRISMA para revisiones sistemáticas que incorporan metaanálisis en red: PRISMA-NMA. Med Clin (Barc) 147(6):262–266. https://doi.org/10.1016/j.medcli.2016.02.025

Article  PubMed  Google Scholar 

Higgins JPT, Altman DG, Gøtzsche PC et al (2011) The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ (Online) 343:7829

Google Scholar 

Parks AG, Gordon PH, Hardcastle JD (1976) A classification of fistula-in-ano. Br J Surg 63(1):1–12. https://doi.org/10.1002/bjs.1800630102

Article  CAS  PubMed  Google Scholar 

Sterne JAC, Savović J, Page MJ et al (2019) RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ 366:l4898. https://doi.org/10.1136/bmj.l4898

Article  PubMed  Google Scholar 

Sterne JA, Hernán MA, Reeves BC et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ (Online). https://doi.org/10.1136/bmj.i4919

Article  PubMed  Google Scholar 

McGuinness LA, Higgins JPT (2021) Risk-of-bias visualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments. Research synthesis methods. Wiley, pp 55–61

Google Scholar 

Barendregt Suhail A, Doi JJ. MetaXL User Guide www.epigear.com

Abdelnaby M, Emile S, El-Said M, Abdallah E, AbdelMawla A (2019) Drained mucosal advancement flap versus rerouting Seton around the internal anal sphincter in treatment of high trans-sphincteric anal fistula: a randomized trial. Int J Surg 72:198–203. https://doi.org/10.1016/j.ijsu.2019.11.008

Article  PubMed  Google Scholar 

Altomare DF, Greco VJ, Tricomi N et al (2011) Seton or glue for trans-sphincteric anal fistulae: a prospective randomized crossover clinical trial. Colorectal Dis 13(1):82–86. https://doi.org/10.1111/j.1463-1318.2009.02056.x

Article  CAS  PubMed  Google Scholar 

Bondi J, Avdagic J, Karlbom U et al (2017) Randomized clinical trial comparing collagen plug and advancement flap for trans-sphincteric anal fistula. Br J Surg 104(9):1160–1166. https://doi.org/10.1002/bjs.10549

Article  CAS  PubMed  Google Scholar 

de la Portilla F, Muñoz-Cruzado MVD, Maestre MV et al (2019) Platelet-rich plasma (PRP) versus fibrin glue in cryptogenic fistula-in-ano: a phase III single-center, randomized, double-blind trial. Int J Colorectal Dis 34(6):1113–1119. https://doi.org/10.1007/s00384-019-03290-6

Article  PubMed  Google Scholar 

Garcia-Arranz M, Garcia-Olmo D, Herreros MD et al (2020) Autologous adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistula: a randomized clinical trial with long-term follow-up. Stem Cells Transl Med 9(3):295–301. https://doi.org/10.1002/sctm.19-0271

Article  CAS  PubMed  Google Scholar 

Garcia-Olmo D, Herreros D, Pascual I et al (2009) Expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase ii clinical trial. Dis Colon Rectum 52(1):79–86. https://doi.org/10.1007/DCR.0b013e3181973487

Article  PubMed  Google Scholar 

Herreros MD, Garcia-Arranz M, Guadalajara H et al (2012) Autologous expanded adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistulas: a phase III randomized clinical trial (FATT 1: Fistula advanced therapy trial 1) and long-term evaluation. Dis Colon Rectum 55(7):762–772. https://doi.org/10.1097/DCR.0b013e318255364a

Article  CAS  PubMed  Google Scholar 

Jayne DG, Scholefield J, Tolan D et al (2021) A multicenter randomized controlled trial comparing safety, efficacy, and cost-effectiveness of the surgisis anal fistula plug versus surgeon’s preference for transsphincteric Fistula-in-Ano: the FIAT trial. Ann Surg 273(3):433–441. https://doi.org/10.1097/SLA.0000000000003981

Article  PubMed  Google Scholar 

Madbouly KM, El SW, Abbas KS et al (2014) Ligation of intersphincteric fistula tract versus mucosal advancement flap in patients with high transsphincteric fistula-in-ano: a prospective randomized trial. Dis Colon Rectum 57(10):1202–1208. https://doi.org/10.1097/DCR.0000000000000194

Article  PubMed  Google Scholar 

Mushaya C, Bartlett L, Schulze B et al (2012) Ligation of intersphincteric fistula tract compared with advancement flap for complex anorectal fistulas requiring initial seton drainage. Am J Surg 204(3):283–289. https://doi.org/10.1016/j.amjsurg.2011.10.025

Article  PubMed  Google Scholar 

Ortiz H, Marzo J, Ciga MA et al (2009) Randomized clinical trial of anal fistula plug versus endorectal advancement flap for the treatment of high cryptoglandular fistula in ano. Br J Surg 96(6):608–612. https://doi.org/10.1002/bjs.6613

Article  CAS  PubMed  Google Scholar 

Perez F, Arroyo A, Serrano P et al (2006) Randomized clinical and manometric study of advancement flap versus fistulotomy with sphincter reconstruction in the management of complex fistula-in-ano. Am J Surg 192(1):34–40. https://doi.org/10.1016/j.amjsurg.2006.01.028

Article  PubMed  Google Scholar 

Siddique S, Changazi SH, Bhatti S et al (2022) Outcomes in high perianal fistula repair using video-assisted anal fistula treatment compared with seton use: a randomized controlled trial. Cureus. https://doi.org/10.7759/cureus.22166

Article  PubMed  PubMed Central  Google Scholar 

Sørensen KM, Möller S, Qvist N (2021) Video-assisted anal fistula treatment versus fistulectomy and sphincter repair in the treatment of high cryptoglandular anal fistula: a randomized clinical study. BJS Open. https://doi.org/10.1093/bjsopen/zrab097

Article  PubMed  PubMed Central  Google Scholar 

Van Der Hagen SJ, Baeten CG, Soeters PB et al (2011) Staged mucosal advancement flap versus staged fibrin sealant in the treatment of complex perianal fistulas. Gastroenterol Res Pract. https://doi.org/10.1155/2011/186350

Article  PubMed  PubMed Central  Google Scholar 

Van Koperen PJ, Bemelman WA, Gerhards MF et al (2011) The anal fistula plug treatment compared with the mucosal advancement flap for cryptoglandular high transsphincteric perianal fistula: a double-blinded multicenter randomized trial. Dis Colon Rectum 54(4):387–393. https://doi.org/10.1007/DCR.0b013e318206043e

Article  PubMed  Google Scholar 

Wang Q, He Y, Shen J (2017) The best surgical strategy for anal fistula based on a network meta-analysis. Oncotarget 8(58):99075–99084. https://doi.org/10.18632/oncotarget.21836

Article  PubMed  PubMed Central  Google Scholar 

Huang H, Ji L, Gu Y et al (2022) Efficacy and safety of sphincter-preserving surgery in the treatment of complex anal fistula: a network meta-analysis. Front Surg 9:825166. https://doi.org/10.3389/fsurg.2022.825166

Article  PubMed  PubMed Central  Google Scholar 

Warsinggih AC, Faruk M (2024) Optimum management for complex anal fistula: A network meta-analysis of randomized controlled trials. Surg Open Sci 18:117–122. https://doi.org/10.1016/j.sopen.2024.03.003

Article  CAS  PubMed  PubMed Central  Google Scholar 

An Y, Gao J, Xu J et al (2024) Efficacy and safety of 13 surgical techniques for the treatment of complex anal fistula, non-Crohn CAF: a systematic review and network meta-analysis. Int J Surg 110(1):441–452. https://doi.org/10.1097/JS9.0000000000000776

Article  PubMed  Google Scholar 

Bhat S, Xu W, Varghese C et al (2023) Efficacy of different surgical treatments for management of anal fistula: a network meta-analysis. Tech Coloproctol 27(10):827–845. https://doi.org/10.1007/s10151-023-02845-8

Comments (0)

No login
gif