Perspectives on mitochondrial dysfunction in the regeneration of aging skeletal muscle

Dumont NA, Wang YX, Rudnicki MA. Intrinsic and extrinsic mechanisms regulating satellite cell function. Development. 2015;142(9):1572–81. https://doi.org/10.1242/dev.114223.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Seale P, Asakura A, Rudnicki MA. The potential of muscle stem cells. Dev Cell. 2001;1(3):333–42. https://doi.org/10.1016/s1534-5807(01)00049-1.

Article  CAS  PubMed  Google Scholar 

Mauro A. Satellite cell of skeletal muscle fibers. J Biophys Biochem Cytol. 1961;9(2):493–5. https://doi.org/10.1083/jcb.9.2.493.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Scharner J, Zammit PS. The muscle satellite cell at 50: the formative years. Skelet Muscle. 2011;1:28. https://doi.org/10.1186/2044-5040-1-28.

Article  PubMed  PubMed Central  Google Scholar 

Short KR, Bigelow ML, Kahl J, Singh R, Coenen-Schimke J, Raghavakaimal S, et al. Decline in skeletal muscle mitochondrial function with aging in humans. Proc Natl Acad Sci USA. 2005;102(15):5618–23. https://doi.org/10.1073/pnas.0501559102.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brack AS, Rando TA. Tissue-specific stem cells: lessons from the skeletal muscle satellite cell. Cell Stem Cell. 2012;10(5):504–14. https://doi.org/10.1016/j.stem.2012.04.001.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheung TH, Rando TA. Molecular regulation of stem cell quiescence. Nat Rev Mol Cell Biol. 2013. https://doi.org/10.1038/nrm3591.10.1038/nrm3591.

Article  PubMed  PubMed Central  Google Scholar 

Wang YX, Rudnicki MA. Satellite cells, the engines of muscle repair. Nat Rev Mol Cell Biol. 2011;13(2):127–33. https://doi.org/10.1038/nrm3265.

Article  CAS  PubMed  Google Scholar 

Kuang S, Gillespie MA, Rudnicki MA. Niche regulation of muscle satellite cell self-renewal and differentiation. Cell Stem Cell. 2008;2(1):22–31. https://doi.org/10.1016/j.stem.2007.12.012.

Article  CAS  PubMed  Google Scholar 

Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, et al. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science. 2007;317(5839):807–10. https://doi.org/10.1126/science.1144090.

Article  CAS  PubMed  Google Scholar 

Blau HM, Cosgrove BD, Ho ATV. The central role of muscle stem cells in regenerative failure with aging. Nat Med. 2015;21(8):854–62. https://doi.org/10.1038/nm.3918.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Benevenga NJ, Blemings KP. Unique aspects of lysine nutrition and metabolism. J Nutr. 2007;137(6 Suppl 2):1610S-1615S. https://doi.org/10.1093/jn/137.6.1610S.

Article  CAS  PubMed  Google Scholar 

Dodgson SJ, Forster RE, Storey BT, Mela L. Mitochondrial carbonic anhydrase. Proc Natl Acad Sci USA. 1980;77(9):5562–6. https://doi.org/10.1073/pnas.77.9.5562.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y, et al. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature. 2011;476(7360):341–5. https://doi.org/10.1038/nature10234.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Palty R, Silverman WF, Hershfinkel M, Caporale T, Sensi SL, Parnis J, et al. NCLX is an essential component of mitochondrial Na+/Ca2+ exchange. Proc Natl Acad Sci USA. 2010;107(1):436–41. https://doi.org/10.1073/pnas.0908099107.

Article  CAS  PubMed  Google Scholar 

Nesci S, Trombetti F, Pagliarani A. Nicotinamide nucleotide transhydrogenase as a sensor of mitochondrial biology. Trends Cell Biol. 2020;30(1):1–3. https://doi.org/10.1016/j.tcb.2019.11.001.

Article  CAS  PubMed  Google Scholar 

Picard M, Shirihai OS. Mitochondrial signal transduction. Cell Metab. 2022;34(11):1620–53. https://doi.org/10.1016/j.cmet.2022.10.008.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, et al. NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 2016;352(6292):1436–43. https://doi.org/10.1126/science.aaf2693.

Article  CAS  PubMed  Google Scholar 

Hood DA, Memme JM, Oliveira AN, Triolo M. Maintenance of skeletal muscle mitochondria in health, exercise, and aging. Annu Rev Physiol. 2019;81(1):19–41. https://doi.org/10.1146/annurev-physiol-020518-114310.

Article  CAS  PubMed  Google Scholar 

Vasilaki A, Jackson MJ. Role of reactive oxygen species in the defective regeneration seen in aging muscle. Free Radic Biol Med. 2013;65:317–23. https://doi.org/10.1016/j.freeradbiomed.2013.07.008.

Article  CAS  PubMed  Google Scholar 

Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, et al. Geroscience: linking aging to chronic disease. Cell. 2014;159(4):709–13. https://doi.org/10.1016/j.cell.2014.10.039.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rando TA, Wyss-Coray T. Asynchronous, contagious and digital aging. Nat Aging. 2021;1(1):29–35. https://doi.org/10.1038/s43587-020-00015-1.

Article  PubMed  PubMed Central  Google Scholar 

Bodine SC, Sinha I, Sweeney HL. Mechanisms of skeletal muscle atrophy and molecular circuitry of stem cell fate in skeletal muscle regeneration and aging. J Gerontol Ser A. 2023;78(Supplement_1):14–8. https://doi.org/10.1093/gerona/glad023.

Article  Google Scholar 

Kuang S, Kuroda K, Le Grand F, Rudnicki MA. Asymmetric self-renewal and commitment of satellite stem cells in muscle. Cell. 2007;129(5):999–1010. https://doi.org/10.1016/j.cell.2007.03.044.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Conboy IM, Conboy MJ, Smythe GM, Rando TA. Notch-mediated restoration of regenerative potential to aged muscle. Science. 2003;302(5650):1575–7. https://doi.org/10.1126/science.1087573.

Article  CAS  PubMed  Google Scholar 

Scicchitano BM, Rizzuto E, Musarò A. Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1. Aging (Albany NY). 2009;1(5):451–7. https://doi.org/10.18632/aging.100050.

Article  CAS  PubMed  Google Scholar 

Jamieson CHM, Weissman IL. Stem-cell aging and pathways to precancer evolution. N Engl J Med. 2023;389(14):1310–9. https://doi.org/10.1056/NEJMra2304431.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Price FD, von Maltzahn J, Bentzinger CF, Dumont NA, Yin H, Chang NC, et al. Inhibition of JAK-STAT signaling stimulates adult satellite cell function. Nat Med. 2014;20(10):1174–81.

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