Águeda-Pinto A, Esteves PJ (2018) The evolution of S100A7 in primates: a model of concerted and birth-and-death evolution. Immunogenetics 71(1):25–33. https://doi.org/10.1007/s00251-018-1079-x

Article  CAS  PubMed  Google Scholar 

Buonocore F, Kühnen P, Suntharalingham JP, Del Valle I, Digweed M, Stachelscheid H, Khajavi N, Didi M, Brady AF, Blankenstein O, Procter AM, Dimitri P, Wales JK, Ghirri P, Knöbl D, Strahm B, Erlacher M, Wlodarski MW, Chen W, Achermann JC (2017) Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans. J Clin Investig 127(5):1700–1713. https://doi.org/10.1172/jci91913

Article  PubMed  PubMed Central  Google Scholar 

Côrte-Real JV, Baldauf H-M, Abrantes J, Esteves PJ (2021) Evolution of the guanylate binding protein (GBP) genes: emergence of GBP7 genes in primates and further acquisition of a unique GBP3 gene in simians. Mol Immunol 132:79–81. https://doi.org/10.1016/j.molimm.2021.01.025

Article  CAS  PubMed  Google Scholar 

Crooks GE, Hon G, Chandonia JM, Brenner SE (2004) WebLogo: A sequence logo generator. Genome Res 14:1188–1190. https://doi.org/10.1101/gr.849004

Article  CAS  PubMed  PubMed Central  Google Scholar 

Davidsson J, Puschmann A, Tedgård U, Bryder D, Nilsson L, Cammenga J (2018) SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies. Leukemia. https://doi.org/10.1038/s41375-018-0074-4

Article  PubMed  PubMed Central  Google Scholar 

Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp Ser 41:3

Legrand A, Dahoui C, De La Myre Mory C, Noy K, Guiguettaz L, Versapuech M, Loyer C, Pillon M, Wcislo M, Guéguen L, Berlioz-Torrent C, Cimarelli A, Mateo M, Fiorini F, Ricci EP, Etienne L (2024) SAMD9L acts as an antiviral factor against HIV-1 and primate lentiviruses by restricting viral and cellular translation. PLoS Biol. https://doi.org/10.1371/journal.pbio.3002696

Article  PubMed  PubMed Central  Google Scholar 

Letunic I, Bork P (2024) Interactive tree of life (iTOL) v6: recent updates to the phylogenetic tree display and annotation tool. Nucleic Acids Res. https://doi.org/10.1093/nar/gkae268

Article  PubMed  PubMed Central  Google Scholar 

Li CF, MacDonald JR, Wei RY, Ray J, Lau K, Kandel C, Koffman R, Bell S, Scherer SW, Alman BA (2007) Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse. BMC Genomics. https://doi.org/10.1186/1471-2164-8-92

Article  PubMed  PubMed Central  Google Scholar 

Matos AL, Liu J, McFadden G, Esteves PJ (2013) Evolution and divergence of the mammalian SAMD9/SAMD9L gene family. BMC Evol Bio. https://doi.org/10.1186/1471-2148-13-121

Article  Google Scholar 

Mekhedov SL, Makarova KS, Koonin EV (2017) The complex domain architecture of SAMD9 family proteins, predicted STAND-like NTPases, suggests new links to inflammation and apoptosis. Biol Direct. https://doi.org/10.1186/s13062-017-0185-2

Article  PubMed  PubMed Central  Google Scholar 

Meng X, Zhang F, Yan B, Si C, Honda H, Nagamachi A, Sun L, Xiang Y (2018) A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection. PLoS Pathog. https://doi.org/10.1371/journal.ppat.1006884

Article  PubMed  PubMed Central  Google Scholar 

Nei M, Gu X, Sitnikova T (1997) Evolution by the birth-and-death process in multigene families of the vertebrate immune system. Proc Natl Acad Sci U S A 94(15):7799–7806. https://doi.org/10.1073/pnas.94.15.7799

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pappas DJ, Coppola G, Gabatto PA, Gao F, Geschwind DH, Oksenberg JR, Baranzini SE (2009) Longitudinal system-based analysis of transcriptional responses to type I interferons. Physiol Genomics 38(3):362–371. https://doi.org/10.1152/physiolgenomics.00058.2009

Article  CAS  PubMed  Google Scholar 

Peng S, Meng X, Zhang F, Pathak PK, Chaturvedi J, Coronado J, Morales M, Mao Y, Qian S, Deng J, Xiang Y (2022) Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L. Proc Natl Acad Sci U S A. https://doi.org/10.1073/pnas.2116550119

Article  PubMed  PubMed Central  Google Scholar 

Perelman P, Johnson WE, Roos C, Seuánez HN, Horvath JE, Moreira MaM, Kessing B, Pontius J, Roelke M, Rumpler Y, Schneider MPC, Silva A, O’Brien SJ, Pecon-Slattery J (2011) A molecular phylogeny of living primates. PLoS Genet 7(3):e1001342. https://doi.org/10.1371/journal.pgen.1001342

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pozzi L, Hodgson JA, Burrell AS, Sterner KN, Raaum RL, Disotell TR (2014) Primate phylogenetic relationships and divergence dates inferred from complete mitochondrial genomes. Mol Phylogenet Evol. https://doi.org/10.1016/j.ympev.2014.02.023

Article  PubMed  PubMed Central  Google Scholar 

Sahoo SS, Pastor VB, Goodings C, Voss RK, Kozyra EJ, Szvetnik A, Noellke P, Dworzak M, Starý J, Locatelli F, Masetti R, Schmugge M, De Moerloose B, Catala A, Kállay K, Turkiewicz D, Hasle H, Buechner J, Jahnukainen K, Wlodarski MW (2021) Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes. Nat Med 27(10):1806–1817. https://doi.org/10.1038/s41591-021-01511-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sahoo SS, Erlacher M, Wlodarski MW (2025) Genetic and clinical spectrum of SAMD9 and SAMD9L syndromes: from variant interpretation to patient management. Blood 145(5):475–485. https://doi.org/10.1182/blood.2022017717

Article  CAS  PubMed  Google Scholar 

Schelle L, Abrantes J, Baldauf H, Esteves PJ (2023) Evolution of primate interferon-induced transmembrane proteins (IFITMs): a story of gain and loss with a differentiation into a canonical cluster and IFITM retrogenes. Front Microbiol. https://doi.org/10.3389/fmicb.2023.1213685

Article  PubMed  PubMed Central  Google Scholar 

Schneider TD, Stephens RM (1990) Sequence logos: a new way to display consensus sequences. Nucleic Acids Res 18:6097–6100. https://doi.org/10.1093/nar/18.20.6097

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tamura K, Stecher G, Kumar S (2021) MEGA11: molecular evolutionary genetics analysis version 11. Mol Biol Evol. https://doi.org/10.1093/molbev/msab120

Article  PubMed  PubMed Central  Google Scholar 

Welter AL, Machida YJ (2022) Functions and evolution of FAM111 serine proteases. Front Mol Biosci. https://doi.org/10.3389/fmolb.2022.1081166

Article  PubMed  PubMed Central  Google Scholar 

Zhang J, Webb DM (2004) Rapid evolution of primate antiviral enzyme APOBEC3G. Hum Mol Genet 13(16):1785–1791. https://doi.org/10.1093/hmg/ddh183

Article  CAS  PubMed  Google Scholar 

Zhang F, Meng X, Townsend MB, Satheshkumar PS, Xiang Y (2019) Identification of CP77 as the third orthopoxvirus SAMD9 and SAMD9L inhibitor with unique specificity for a rodent SAMD9L. J Virol. https://doi.org/10.1128/jvi.00225-19

Article  PubMed  PubMed Central  Google Scholar 

Zhang F, Ji Q, Chaturvedi J, Morales M, Mao Y, Meng X, Dong L, Deng J, Qian S, Xiang Y (2023) Human SAMD9 is a poxvirus-activatable anticodon nuclease inhibiting codon-specific protein synthesis. Sci Adv. https://doi.org/10.1126/sciadv.adh8502

Article  PubMed  PubMed Central  Google Scholar 

Zmasek CM, Zhang Q, Ye Y, Godzik A (2007) Surprising complexity of the ancestral apoptosis network. Genome Biol. https://doi.org/10.1186/gb-2007-8-10-r226

Article  PubMed  PubMed Central  Google Scholar