Bade BC, Dela Cruz CS. Lung cancer 2020: epidemiology, etiology, and prevention. Clin Chest Med. 2020;41(1):1–24.

Article  PubMed  Google Scholar 

Reck M, et al. Metastatic non-small-cell lung cancer (NSCLC): ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2014;25(Suppl 3):iii27–39.

Article  PubMed  Google Scholar 

Duma N, Santana-Davila R, Molina JR. Non-small cell lung cancer: epidemiology, screening, diagnosis, and treatment. Mayo Clin Proc. 2019;94(8):1623–40.

Article  CAS  PubMed  Google Scholar 

Didkowska J, et al. Lung cancer epidemiology: contemporary and future challenges worldwide. Ann Transl Med. 2016;4(8):150.

Article  PubMed  PubMed Central  Google Scholar 

Mun EJ, et al. Tumor-treating fields: a fourth modality in cancer treatment. Clin Cancer Res. 2018;24(2):266–75.

Article  CAS  PubMed  Google Scholar 

Hassannia B, Vandenabeele P, Vanden Berghe T. Targeting ferroptosis to iron out cancer. Cancer Cell. 2019;35(6):830–49.

Article  CAS  PubMed  Google Scholar 

Hu C, et al. PPP1R3A inhibits osteogenesis and negatively regulates intracellular calcium levels in calcific tendinopathy. iScience. 2023;26(10):107784.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ursini F, Maiorino M. Lipid peroxidation and ferroptosis: the role of GSH and GPx4. Free Radic Biol Med. 2020;152:175–85.

Article  CAS  PubMed  Google Scholar 

Chen X, et al. Ferroptosis: machinery and regulation. Autophagy. 2021;17(9):2054–81.

Article  CAS  PubMed  Google Scholar 

Lei G, Zhuang L, Gan B. The roles of ferroptosis in cancer: tumor suppression, tumor microenvironment, and therapeutic interventions. Cancer Cell. 2024;42(4):513–34.

Article  CAS  PubMed  Google Scholar 

Zhao Y, et al. The role of Erastin in ferroptosis and its prospects in cancer therapy. Onco Targets Ther. 2020;13:5429–41.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Y, et al. Erastin induces ferroptosis via ferroportin-mediated iron accumulation in endometriosis. Hum Reprod. 2021;36(4):951–64.

Article  CAS  PubMed  Google Scholar 

Pan X, et al. Erastin decreases radioresistance of NSCLC cells partially by inducing GPX4-mediated ferroptosis. Oncol Lett. 2019;17(3):3001–8.

CAS  PubMed  PubMed Central  Google Scholar 

Mou Y, et al. Ferroptosis, a new form of cell death: opportunities and challenges in cancer. J Hematol Oncol. 2019;12(1):34.

Article  PubMed  PubMed Central  Google Scholar 

Li D, et al. CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1. Oncogene. 2023;42(2):83–98.

Article  PubMed  Google Scholar 

Shen L, et al. PHGDH inhibits ferroptosis and promotes malignant progression by upregulating SLC7A11 in bladder cancer. Int J Biol Sci. 2022;18(14):5459–74.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang X, et al. Curcumin induces ferroptosis in non-small-cell lung cancer via activating autophagy. Thorac Cancer. 2021;12(8):1219–30.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu X-Y, Wei D-G, Li R-S. Capsaicin induces ferroptosis of NSCLC by regulating SLC7A11/GPX4 signaling in vitro. Sci Rep. 2022;12(1):11996.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maheshwari C, et al. Isolation, characterization, and autophagy function of BECN1-splicing isoforms in cancer cells. Biomolecules. 2022. https://doi.org/10.3390/biom12081069.

Article  PubMed  PubMed Central  Google Scholar 

Kihara A, et al. Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep. 2001;2(4):330–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhong Y, et al. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol. 2009;11(4):468–76.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wijshake T, et al. Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin. Proc Natl Acad Sci U S A. 2021;118(5):e2020478118.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang H, et al. Decreased BECN1 mRNA expression in human breast cancer is associated with Estrogen Receptor-Negative subtypes and poor prognosis. EBioMedicine. 2015;2(3):255–63.

Article  PubMed  PubMed Central  Google Scholar 

Valente G et al. Expression and clinical significance of the autophagy proteins BECLIN 1 and LC3 in ovarian cancer. Biomed Res Int, 2014. 2014: p. 462658.

Zhang MY, et al. Beclin 1 expression is closely linked to colorectal carcinogenesis and distant metastasis of colorectal carcinoma. Int J Mol Sci. 2014;15(8):14372–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang MY, et al. Effects of Beclin 1 overexpression on aggressive phenotypes of colon cancer cells. Oncol Lett. 2019;17(2):2441–50.

CAS  PubMed  Google Scholar 

Jiang ZF, et al. Decreased expression of Beclin-1 and LC3 in human lung cancer. Mol Biol Rep. 2012;39(1):259–67.

Article  CAS  PubMed  Google Scholar 

Yu S, et al. Loss of Beclin1 expression and Nrf2 overexpression are associated with poor survival of patients with Non-Small cell lung cancer. Anticancer Agents Med Chem. 2018;18(12):1680–7.

Article  CAS  PubMed  Google Scholar 

Chang SH, et al. Beclin1-induced autophagy abrogates radioresistance of lung cancer cells by suppressing osteopontin. J Radiat Res. 2012;53(3):422–32.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Majdoul S, et al. Peptides derived from evolutionarily conserved domains in Beclin-1 and Beclin-2 enhance the entry of lentiviral vectors into human cells. J Biol Chem. 2017;292(45):18672–81.

Article  CAS  PubMed  PubMed Central  Google Scholar 

He Y, Lu H, Zhao Y. Development of an autophagy activator from class III PI3K complexes, Tat-BECN1 peptide: mechanisms and applications. Front Cell Dev Biol. 2022;10:851166.

Article  PubMed  PubMed Central  Google Scholar 

Yan K, et al. PM2. 5 inhibits system Xc-activity to induce ferroptosis by activating the AMPK-Beclin1 pathway in acute lung injury. Ecotoxicol Environ Saf. 2022;245:114083.

Article  CAS  PubMed