Medical-legal partnerships (MLPs) are healthcare delivery models that involve a multi-disciplinary team including clinicians, lawyers, social workers, and case managers, working together to address legal issues of vulnerable patient populations. This practice model aims to improve patient outcomes and population health by integrating legal services into clinical settings to address health-harming legal needs. This article will review the history of MLPs in the United States and the status of the MLPs in the NICU setting. In addition, this article will describe the benefits and challenges of implementing a MLP and offer insights into how this partnership assists NICU patients and their families.