Microaspiration dynamics and “bio-inoculum intensity”: Deciphering the clinical paradox of tapered cuffs – Response to Chen et al.

ElsevierVolume 93, April 2026, 104320Intensive and Critical Care NursingAuthor links open overlay panelSuwen Li, Xing Xin, Chenxin Ye, Gendi LuShow moreAccess through your organization

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The “Static-Dynamic Paradox” and “Reservoir-Bolus” mechanisms proposed herein remain theoretical; clinical validation is required to confirm their impact on VAP outcomes.

CRediT authorship contribution statement

Suwen Li: Writing – review & editing, Writing – original draft. Xing Xin: Writing – original draft. Chenxin Ye: Writing – original draft. Gendi Lu: Writing – original draft.

Funding

This study received no external funding.

Declaration of competing interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

References (5)L. Chen et al.Endotracheal tube cuff modifications for VAP prevention: bridging evidence and clinical practice - Letter on Li S et al.

Intensive Crit Care Nurs

(2025)

S. Li et al.Tracheal tube cuff materials, shapes, and coatings in the prevention of ventilator-associated pneumonia: a network meta-analysis and systematic review

Intensive Crit Care Nurs

(2026)

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