Kiel MJ, Yilmaz OH, Iwashita T et al (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121:1109–1121. https://doi.org/10.1016/j.cell.2005.05.026
Article CAS PubMed Google Scholar
Sugiyama T, Kohara H, Noda M, Nagasawa T (2006) Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 25:977–988. https://doi.org/10.1016/j.immuni.2006.10.016
Article CAS PubMed Google Scholar
Zhou BO, Yue R, Murphy MM et al (2014) Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow. Cell Stem Cell 15:154–168. https://doi.org/10.1016/j.stem.2014.06.008
Article CAS PubMed PubMed Central Google Scholar
Méndez-Ferrer S, Michurina TV, Ferraro F et al (2010) Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466:829–834. https://doi.org/10.1038/nature09262
Article CAS PubMed PubMed Central Google Scholar
Zhao M, Tao F, Venkatraman A et al (2019) N-cadherin-expressing bone and marrow stromal progenitor cells maintain reserve hematopoietic stem cells. Cell Rep 26:652-669.e6. https://doi.org/10.1016/j.celrep.2018.12.093
Article CAS PubMed PubMed Central Google Scholar
Ono N, Ono W, Mizoguchi T et al (2014) Vasculature-associated cells expressing nestin in developing bones encompass early cells in the osteoblast and endothelial lineage. Dev Cell 29:330–339. https://doi.org/10.1016/j.devcel.2014.03.014
Article CAS PubMed PubMed Central Google Scholar
Omatsu Y, Sugiyama T, Kohara H et al (2010) The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche. Immunity 33:387–399. https://doi.org/10.1016/j.immuni.2010.08.017
Article CAS PubMed Google Scholar
Ding L, Morrison SJ (2013) Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Nature 495:231–235. https://doi.org/10.1038/nature11885
Article CAS PubMed PubMed Central Google Scholar
Greenbaum A, Hsu Y-MS, Day RB et al (2013) CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature 495:227–230. https://doi.org/10.1038/nature11926
Article CAS PubMed PubMed Central Google Scholar
Broudy VC (1997) Stem cell factor and hematopoiesis. Blood 90:1345–1364
Article CAS PubMed Google Scholar
Ding L, Saunders TL, Enikolopov G, Morrison SJ (2012) Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 481:457–462. https://doi.org/10.1038/nature10783
Article CAS PubMed PubMed Central Google Scholar
Asada N, Kunisaki Y, Pierce H et al (2017) Differential cytokine contributions of perivascular haematopoietic stem cell niches. Nat Cell Biol 19:214–223. https://doi.org/10.1038/ncb3475
Article CAS PubMed PubMed Central Google Scholar
Mizoguchi T, Pinho S, Ahmed J et al (2014) Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development. Dev Cell 29:340–349. https://doi.org/10.1016/j.devcel.2014.03.013
Article CAS PubMed PubMed Central Google Scholar
Pineault KM, Song JY, Kozloff KM et al (2019) Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life. Nat Commun 10:3168. https://doi.org/10.1038/s41467-019-11100-4
Article CAS PubMed PubMed Central Google Scholar
Shu HS, Liu YL, Tang XT et al (2021) Tracing the skeletal progenitor transition during postnatal bone formation. Cell Stem Cell 28:2122-2136.e3. https://doi.org/10.1016/j.stem.2021.08.010
Article CAS PubMed Google Scholar
Ono N, Ono W, Nagasawa T, Kronenberg HM (2014) A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones. Nat Cell Biol 16:1157–1167. https://doi.org/10.1038/ncb3067
Article CAS PubMed PubMed Central Google Scholar
Mizoguchi T, Ono N (2021) The diverse origin of bone-forming osteoblasts. J Bone Miner Res 36:1432–1447. https://doi.org/10.1002/jbmr.4410
Article PubMed PubMed Central Google Scholar
Seike M, Omatsu Y, Watanabe H et al (2018) Stem cell niche-specific Ebf3 maintains the bone marrow cavity. Genes Dev 32:359–372. https://doi.org/10.1101/gad.311068.117
Article CAS PubMed PubMed Central Google Scholar
Omatsu Y, Seike M, Sugiyama T et al (2014) Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation. Nature 508:536–540. https://doi.org/10.1038/nature13071
Article CAS PubMed Google Scholar
Nakahara F, Borger DK, Wei Q et al (2019) Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells. Nat Cell Biol 21:560–567. https://doi.org/10.1038/s41556-019-0308-3
Article CAS PubMed PubMed Central Google Scholar
Baccin C, Al-Sabah J, Velten L et al (2020) Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization. Nat Cell Biol 22:38–48. https://doi.org/10.1038/s41556-019-0439-6
Article CAS PubMed Google Scholar
Matsushita Y, Nagata M, Kozloff KM et al (2020) A wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun 11:332. https://doi.org/10.1038/s41467-019-14029-w
Article CAS PubMed PubMed Central Google Scholar
Shen B, Tasdogan A, Ubellacker JM et al (2021) A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis. Nature 591:438–444. https://doi.org/10.1038/s41586-021-03298-5
Article CAS PubMed PubMed Central Google Scholar
Poulos MG, Guo P, Kofler NM et al (2013) Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis. Cell Rep 4:1022–1034. https://doi.org/10.1016/j.celrep.2013.07.048
Article CAS PubMed PubMed Central Google Scholar
Kunisaki Y, Bruns I, Scheiermann C et al (2013) Arteriolar niches maintain haematopoietic stem cell quiescence. Nature 502:637–643. https://doi.org/10.1038/nature12612
Article CAS PubMed PubMed Central Google Scholar
Itkin T, Gur-Cohen S, Spencer JA et al (2016) Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature 532:323–328. https://doi.org/10.1038/nature17624
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