SCI Abstract

search
+
Bridging skeletal stem cell diversity and human skeletal modeling
Bridging skeletal stem cell diversity and human skeletal modeling
Skeletal stem cells (SSCs) underlie skeletal development, homeostasis, regeneration, and aging, yet their identities and f...
The effects of sequential therapy using anti-resorptive agents after administering once-weekly teriparatide or twice-weekly teriparatide
The effects of sequential therapy using anti-resorptive agents after administering once-weekly teriparatide or twice-weekly teriparatide
Studies launched in Japan on once-weekly teriparatide (1/W-TPTD) and twice-weekly teriparatide (2/W-TPTD) are limited. The...
Association of serum magnesium levels and calcimimetic use: fractures and cardiovascular events in Japanese haemodialysis patients
Association of serum magnesium levels and calcimimetic use: fractures and cardiovascular events in Japanese haemodialysis patients
Though low serum magnesium (Mg) levels are associated with adverse outcomes in patients on haemodialysis, the interaction ...
Trends in the incidence of secondary hip fractures and osteoporosis treatment in Japan (FY2012–FY2023)
Trends in the incidence of secondary hip fractures and osteoporosis treatment in Japan (FY2012–FY2023)
This study aimed to clarify trends in the incidence of secondary hip fractures and pharmacotherapy after primary fractures...
How postmenopausal osteoporosis influences epidemiology and clinical features of CRPS-1
How postmenopausal osteoporosis influences epidemiology and clinical features of CRPS-1
This study aimed to investigate the relationship between Osteoporosis (OP) and Complex Regional Pain Syndrome type 1 (CRPS...
Autoimmune osteomalacia: a novel FGF23-related hypophosphatemic osteomalacia
Autoimmune osteomalacia: a novel FGF23-related hypophosphatemic osteomalacia
Fibroblast growth factor 23 (FGF23)-related hypophosphatemic rickets/osteomalacia arises from excessive FGF23 activity, wi...
Alterations in bone-related hormones and genes expression in femoral bone of polycystic ovary syndrome rats
Alterations in bone-related hormones and genes expression in femoral bone of polycystic ovary syndrome rats
Polycystic ovary syndrome (PCOS) has been associated with conflicting effects on bone mass, underscoring the need for deep...
Endothelial diversity in bone vasculature coordinates osteogenesis and hematopoiesis
Endothelial diversity in bone vasculature coordinates osteogenesis and hematopoiesis
Bone is a highly vascularized organ, and the vasculature in bone not only delivers oxygen and nutrients but also helps det...
Causal association between gut microbiota and osteonecrosis in European populations: a two-sample Mendelian randomization analysis
Causal association between gut microbiota and osteonecrosis in European populations: a two-sample Mendelian randomization analysis
Recent studies have linked gut microbiota composition to osteonecrosis, but the causal relationship remains unclear. Clari...
Evocalcet improved the PTH–calcium setpoint and suppressed parathyroid proliferation in mice model of primary hyperparathyroidism
Evocalcet improved the PTH–calcium setpoint and suppressed parathyroid proliferation in mice model of primary hyperparathyroidism
Evocalcet is an allosteric modulator of the calcium-sensing receptor (CaSR) that effectively suppresses parathyroid hormon...
Osteoporosis risk with sodium–glucose cotransporter 2 inhibitors versus thiazolidinediones in older women with diabetes
Osteoporosis risk with sodium–glucose cotransporter 2 inhibitors versus thiazolidinediones in older women with diabetes
This study aimed to compare the risk of osteoporosis between sodium–glucose cotransporter 2 inhibitors (SGLT2is) and...
Inflammaging in periodontal, periapical, and malignancy-associated disease: drivers of alveolar bone loss and repair
Inflammaging in periodontal, periapical, and malignancy-associated disease: drivers of alveolar bone loss and repair
Aging significantly impacts bone metabolism through altered osteoblast/osteoclast dynamics, reduced stem cell regeneration...
Multifunctional LepR⁺ skeletal stem/progenitor cells for bone and marrow homeostasis
Multifunctional LepR⁺ skeletal stem/progenitor cells for bone and marrow homeostasis
Bone is a multifunctional organ that provides structural support and hosts the bone marrow, a key site for hematopoiesis a...
Skeletal stem cell lineages in osteosarcoma and bone metastasis
Skeletal stem cell lineages in osteosarcoma and bone metastasis
Skeletal stem cells (SSCs) and their lineage derivatives play essential roles in bone development, maintenance, and regene...
The bone marrow microenvironment during homeostasis and after myeloablation
The bone marrow microenvironment during homeostasis and after myeloablation
Hematopoietic stem cells (HSCs) are the lifelong source of hematopoietic cells, maintained within the specialized microenv...
Spexin-induced MC3T3-E1 cell-derived exosomes enhance osteoblast differentiation
Spexin-induced MC3T3-E1 cell-derived exosomes enhance osteoblast differentiation
The roles of exosomes in osteoblast differentiation has been widely investigated. Low exosome production from donor cells ...
Bisphosphonates with high bone-resorption-capacity promote osteonecrosis of the jaw development after tooth extraction in mice
Bisphosphonates with high bone-resorption-capacity promote osteonecrosis of the jaw development after tooth extraction in mice
Medication-Related Osteonecrosis of the Jaw (MRONJ) is a condition marked by osteonecrosis of the jaw bone and other sympt...
Locomotive syndrome and increased musculoskeletal disorder incidence in older adults: a prospective study
Locomotive syndrome and increased musculoskeletal disorder incidence in older adults: a prospective study
With the population aging, musculoskeletal disorders increasingly impair older adults’ quality of life and escalatin...
Deciphering the genetic interconnection between sarcopenia and osteoporosis: SCD1
Deciphering the genetic interconnection between sarcopenia and osteoporosis: SCD1
Sarcopenia is closely related to osteoporosis, but the causal direction of these associations remains unclear. This study ...
Increased complications of proximal femur fractures during the COVID-19 pandemic: a nationwide medical claims database study in Japan
Increased complications of proximal femur fractures during the COVID-19 pandemic: a nationwide medical claims database study in Japan
Coronavirus disease 2019 (COVID-19) is a worldwide pandemic, and mortality increases in elderly patients with comorbiditie...
Effects of introducing a new reimbursement scheme on pharmaceutical treatment for osteoporosis after hip fracture
Effects of introducing a new reimbursement scheme on pharmaceutical treatment for osteoporosis after hip fracture
Fracture Liaison Service (FLS) programs are beneficial for reducing the frequency of subsequent fractures and mortality in...
Postoperative risks of type 2 diabetes in elderly hip fracture patients: a propensity score-matched study
Postoperative risks of type 2 diabetes in elderly hip fracture patients: a propensity score-matched study
Type 2 diabetes is associated with an increased risk of fragility fractures, even in individuals with normal or high bone ...
What is the appropriate antibiotic administration to prevent MRONJ development after tooth extraction?
What is the appropriate antibiotic administration to prevent MRONJ development after tooth extraction?
There are no established guidelines for antibiotic administration to prevent the development of medication related-osteone...
Long-term assessment of quality of life in the older patients with fragility hip fracture
Long-term assessment of quality of life in the older patients with fragility hip fracture
Fragility hip fracture (FHF) has been frequently seen in trauma of older people, resulted in decreased mobility and a loss...
Probability of achieving treatments goals with twice-weekly teriparatide followed by bisphosphonate in Japanese postmenopausal osteoporosis
Probability of achieving treatments goals with twice-weekly teriparatide followed by bisphosphonate in Japanese postmenopausal osteoporosis
The purpose of this study is to evaluate the increase in bone mineral density (BMD) and achievement of treatment goals bas...
Independent risk factors and survival prediction in hip refractures patients: insights from a 10-year cohort
Independent risk factors and survival prediction in hip refractures patients: insights from a 10-year cohort
Hip fracture (HF) is one of the leading causes of mortality and disability in older populations. Hip refracture (HRF) is m...
The effect of coffee consumption on three main bone disorders: a Mendelian randomization trial
The effect of coffee consumption on three main bone disorders: a Mendelian randomization trial
Despite a large number of observational studies examining the effect of coffee consumption(CC) on bone disorders(BDs), par...
Efficacy of a single 5 mg zoledronic acid infusion in preventing bone loss and fracture in postmenopausal women with breast cancer
Efficacy of a single 5 mg zoledronic acid infusion in preventing bone loss and fracture in postmenopausal women with breast cancer
Chemotherapy-induced bone loss (CTIBL) is common among breast cancer patients, requiring comprehensive assessment and inte...
Enpp1 mutations promote upregulation of hedgehog signaling in heterotopic ossification with aging
Enpp1 mutations promote upregulation of hedgehog signaling in heterotopic ossification with aging
Heterotopic ossification of the tendon and ligament (HOTL) is a chronic progressive disease that is usually accompanied by...
Incidence of four major osteoporotic fragility fractures among older individuals in Sado, Japan, in 2020
Incidence of four major osteoporotic fragility fractures among older individuals in Sado, Japan, in 2020
This study compared the 2020 incidence of fragility fractures in Sado City with those from 2004 to 2015. Data from patient...
Load More
format_indent_increase