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Moving with the Times: The Health Science Alliance (HSA) Biobank, Pathway to Sustainability
Human biobanks are recognised as vital components of translational research infrastructure. With the growth in personalise...
Biomarker Insights
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Cytokine Profiling in Plasma from Patients with Brain Tumors Versus Healthy Individuals using 2 Different Multiplex Immunoassay Platforms
We compared the performance of two 96-well multiplex immunoassay platforms in assessing plasma cytokine concentrations in ...
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Quality Considerations When Using Tissue Samples for Biomarker Studies in Cancer Research
Tissue obtained from biobanks is frequently employed in biomarker studies. Biomarkers define objective, measurable charact...
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The Assessment of the Usefulness of Selected Markers in the Diagnosis of Chronic Kidney Disease in Children
Introduction:The kidney deterioration, which starts in childhood often leads to end-stage renal failure in the future. The...
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Mind Over Matter: Confronting Challenges in Post-Mortem Brain Biobanking for Glioblastoma Multiforme
Over the past 10 years, there has been limited progress for the treatment of brain cancer and outcomes for patients are no...
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Multiple Sclerosis Biomarker Discoveries by Proteomics and Metabolomics Approaches
Multiple sclerosis (MS) is an autoimmune inflammatory disorder of the central nervous system (CNS) resulting in demyelinat...
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Circadian, Week-to-Week, and Physical Exercise-Induced Variation of Serum Microfibrillar-Associated Protein 4
Serum microfibrillar-associated protein 4 (sMFAP4) has been investigated as a biomarker for various diseases and is demons...
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Companion Diagnostics: State of the Art and New Regulations
Companion diagnostics (CDx) hail promise of improving the drug development process and precision medicine. However, there ...
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Prognostic Utility of Pretreatment Neutrophil-Lymphocyte Ratio in Advanced Larynx Cancer
Purpose:Neutrophil-lymphocyte ratio has been explored as a prognosticator in several cancer types, but its association wit...
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Advancing the Care of Pancreatic Cancer Patients: Moving Beyond Just Tumour Tissue
Biobanking efforts, to establish and grow the pool of available tissue from which evidence on aetiology, therapeutic susce...
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Serum Neurofilament Light as a Biomarker of Traumatic Brain Injury in the Presence of Concomitant Peripheral Injury
Introduction:Serum neurofilament light (NfL) is an emerging biomarker of traumatic brain injury (TBI). However, the effect...
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suPAR Cut-Offs for Risk Stratification in Patients With Symptoms of COVID-19
Objectives:Elevated soluble urokinase Plasminogen Activator Receptor (suPAR) is a biomarker associated with adverse outcom...
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Update on Biomarkers in Spinal Muscular Atrophy
The availability of disease modifying therapies for spinal muscular atrophy (SMA) has created an urgent need to identify c...
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