Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2022;74(3):229–63. https://doi.org/10.3322/caac.21834.
Global cancer burden growing, amidst mounting need for services. Saudi Med J. 2024;45(3):326–7.
Li L, Zhu H, Chen J, Shan L, Xu J. Intervention strategies for cancer-related sarcopenia: a scoping review. Front Nutr. 2025;12:1666547. https://doi.org/10.3389/fnut.2025.1666547.
Article PubMed PubMed Central Google Scholar
Sun Q, Jiang X, Qin R, et al. Sarcopenia among older patients with cancer: a scoping review of the literature. J Geriatr Oncol. 2022;13(7):924–34. https://doi.org/10.1016/j.jgo.2022.03.008.
Article CAS PubMed Google Scholar
Bozzetti F. Age-related and cancer-related sarcopenia: is there a difference? Curr Opin Clin Nutr Metab Care. 2024;27(5):410–8. https://doi.org/10.1097/MCO.0000000000001033.
Article CAS PubMed Google Scholar
Arends J, Strasser F, Gonella S, et al. Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines☆. ESMO Open. 2021;6(3):100092. https://doi.org/10.1016/j.esmoop.2021.100092.
Article CAS PubMed PubMed Central Google Scholar
Kiss N, Loeliger J, Findlay M, et al. Clinical Oncology Society of Australia: position statement on cancer-related malnutrition and sarcopenia. Nutr Diet. 2020;77(4):416–25. https://doi.org/10.1111/1747-0080.12631.
Article PubMed PubMed Central Google Scholar
Jang MK, Park S, Jeon JY, et al. Evaluating the effects of a resistance exercise intervention for sarcopenia in patients receiving neoadjuvant chemotherapy for breast cancer: study protocol for a randomized controlled trial. BMC Cancer. 2025;25(1):1296. https://doi.org/10.1186/s12885-025-14721-9.
Article PubMed PubMed Central Google Scholar
Wang J, Tan S, Wu G. Oral nutritional supplements, physical activity, and sarcopenia in cancer. Curr Opin Clin Nutr Metab Care. 2021;24(3):223–8. https://doi.org/10.1097/MCO.0000000000000736.
Article CAS PubMed Google Scholar
Papadopetraki A, Giannopoulos A, Maridaki M, et al. The role of exercise in cancer-related sarcopenia and sarcopenic obesity. Cancers (Basel). 2023;15(24):5856. https://doi.org/10.3390/cancers15245856.
Article CAS PubMed PubMed Central Google Scholar
Aromataris E, Fernandez R, Godfrey CM, Holly C, Khalil H, Tungpunkom P. Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach. Int J Evid Based Healthc. 2015;13(3):132–40. https://doi.org/10.1097/XEB.0000000000000055.
Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2020;372:n71. https://doi.org/10.1136/bmj.n71.
Methley AM, Campbell S, Chew-Graham C, McNally R, Cheraghi-Sohi S. PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews. BMC Health Serv Res. 2014;14(1):579. https://doi.org/10.1186/s12913-014-0579-0.
Article PubMed PubMed Central Google Scholar
Tan TW, Tan HL, Chung YC. Effectiveness of resistance training in preventing sarcopenia among breast cancer patients undergoing chemotherapy: a systematic review and meta-analysis. Worldviews Evid Based Nurs. 2024;21(6):687–94. https://doi.org/10.1111/wvn.12756.
Cao A, Ferrucci LM, Caan BJ, Irwin ML. Effect of exercise on sarcopenia among cancer survivors: a systematic review. Cancers (Basel). 2022;14(3):786. https://doi.org/10.3390/cancers14030786.
Article PubMed PubMed Central Google Scholar
Lee J. The effects of resistance training on muscular strength and hypertrophy in elderly cancer patients: a systematic review and meta-analysis. J Sport Health Sci. 2022;11(2):194–201. https://doi.org/10.1016/j.jshs.2021.02.002.
Article CAS PubMed Google Scholar
Liu R, Gao XY, Wang L. Network meta-analysis of the intervention effects of different exercise measures on sarcopenia in cancer patients. BMC Public Health. 2024;24(1):1281. https://doi.org/10.1186/s12889-024-18493-y.
Article PubMed PubMed Central Google Scholar
Burke D, Brown M, O’Neill C, et al. The effect of lifestyle interventions on sarcopenia in advanced colorectal cancer: a systematic review. J Geriatr Oncol. 2025;16(1):102143. https://doi.org/10.1016/j.jgo.2024.102143.
Article CAS PubMed Google Scholar
Cheema BS, Kilbreath SL, Fahey PP, Delaney GP, Atlantis E. Safety and efficacy of progressive resistance training in breast cancer: a systematic review and meta-analysis. Breast Cancer Res Treat. 2014;148(2):249–68. https://doi.org/10.1007/s10549-014-3162-9.
Article CAS PubMed Google Scholar
Marcantei C, Couret A, King J, Mazeaud S, Armand A, Ennequin G. Effects of exercise training on muscle mass and physical function in patients with hepatocellular carcinoma after diagnosis: a systematic review. Dig Dis Sci. 2024;69(7):2667–80. https://doi.org/10.1007/s10620-024-08441-6.
Lopez P, Newton RU, Taaffe DR, Winters-Stone K, Galvão DA, Buffart LM. Moderators of resistance-based exercise programs’ effect on sarcopenia-related measures in men with prostate cancer previously or currently undergoing androgen deprivation therapy: an individual patient data meta-analysis. J Geriatr Oncol. 2023;14(5):101535. https://doi.org/10.1016/j.jgo.2023.101535.
Article CAS PubMed Google Scholar
Koeppel M, Mathis K, Schmitz KH, Wiskemann J. Muscle hypertrophy in cancer patients and survivors via strength training. A meta-analysis and meta-regression. Crit Rev Oncol Hematol. 2021;163:103371. https://doi.org/10.1016/j.critrevonc.2021.103371.
Clifford B, Koizumi S, Wewege MA, et al. The effect of resistance training on body composition during and after cancer treatment: a systematic review and meta-analysis. Sports Med. 2021;51(12):2527–46. https://doi.org/10.1007/s40279-021-01542-6.
Liu X, Xu X, Cheung DST, et al. The effects of exercise with or without dietary advice on muscle mass, muscle strength, and physical functioning among older cancer survivors: a meta-analysis of randomized controlled trials. J Cancer Surviv. 2024;18(5):1548–56. https://doi.org/10.1007/s11764-023-01396-z.
Padilha CS, Marinello PC, Galvão DA, et al. Evaluation of resistance training to improve muscular strength and body composition in cancer patients undergoing neoadjuvant and adjuvant therapy: a meta-analysis. J Cancer Surviv. 2017;11(3):339–49. https://doi.org/10.1007/s11764-016-0592-x.
Jang MK, Park C, Tussing-Humphreys L, Fernhall B, Phillips S, Doorenbos AZ. The effectiveness of sarcopenia interventions for cancer patients receiving chemotherapy. Cancer Nurs. 2023;46(2):E81–90. https://doi.org/10.1097/NCC.0000000000000957.
Article PubMed PubMed Central Google Scholar
Lopez P, Galvão DA, Taaffe DR, et al. Resistance training in breast cancer patients undergoing primary treatment: a systematic review and meta-regression of exercise dosage. Breast Cancer. 2021;28(1):16–24. https://doi.org/10.1007/s12282-020-01147-3.
Loeliger J, Edbrooke L, Daly RM, et al. Development and Feasibility of an Inpatient Cancer-Related Sarcopenia Pathway at a Major Cancer Centre. Int J Environ Res Public Health. 2022;19(7):4038. https://doi.org/10.3390/ijerph19074038.
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