Langley DB, et al. Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY). Neuropeptides. 2022;92:102231.
Article PubMed CAS Google Scholar
Chen Q-C, Zhang Y. The role of NPY in the regulation of bone metabolism. Front Endocrinol. 2022;13:833485.
Vohra MS, et al. AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity. Eur J Pharmacol. 2022;915:174611.
Article PubMed CAS Google Scholar
Medeiros PJ, et al. Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line. Int J Cancer. 2012;131(2):276–86.
Article PubMed CAS Google Scholar
Pascetta SA, et al. Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling. BMC Cancer. 2023;23(1):494.
Article PubMed PubMed Central CAS Google Scholar
Sigorski D, et al. Neuropeptide Y in cancer—biological functions and potential clinical implications. Cancer Metastasis Rev. 2025;44(1):21.
Article PubMed PubMed Central CAS Google Scholar
Sánchez ML, Rodríguez FD, Coveñas R. Neuropeptide Y peptide family and cancer: antitumor therapeutic strategies. Int J Mol Sci. 2023;24(12):9962.
Article PubMed PubMed Central Google Scholar
Bhat R, et al. NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer. Sci Rep. 2022;12(1):1972.
Article PubMed PubMed Central CAS Google Scholar
Lin S-T, et al. Update on the role of neuropeptide Y and other related factors in breast cancer and osteoporosis. Front Endocrinol. 2021;12:705499.
Fonseca IC, et al. PET imaging of the neuropeptide Y system: a systematic review. Molecules. 2022;27(12):3726.
Article PubMed PubMed Central CAS Google Scholar
Sun W, et al. Serum neuropeptide Y: a potential prognostic marker of intracerebral hemorrhage. Dis Markers. 2021;2021(1):7957013.
PubMed PubMed Central Google Scholar
Liu J, et al. The novel methylation biomarker NPY5R sensitizes breast cancer cells to chemotherapy. Front Cell Dev Biol. 2022;9:798221.
Article PubMed PubMed Central Google Scholar
Sheriff S, et al. Neuropeptide Y Y5 receptor promotes cell growth through extracellular signal-regulated kinase signaling and cyclic AMP inhibition in a human breast cancer cell line. Mol Cancer Res. 2010;8(4):604–14.
Article PubMed CAS Google Scholar
Chakroborty D, et al. Neuropeptide Y, a paracrine factor secreted by cancer cells, is an independent regulator of angiogenesis in colon cancer. Br J Cancer. 2022;127(8):1440–9.
Article PubMed PubMed Central CAS Google Scholar
Dawoud MM, et al. Clinical significance of immunohistochemical expression of neuropeptide Y1 receptor in patients with breast cancer in Egypt. Appl Immunohistochem Mol Morphol. 2021;29(4):277–86.
Article PubMed CAS Google Scholar
Szabo BC, et al. Novel insights into the modulation of the voltage-gated potassium channel KV1. 3 activation gating by membrane ceramides. J Lipid Res. 2024;65(8):100596.
Article PubMed PubMed Central Google Scholar
Zúñiga L, et al. Potassium channels as a target for cancer therapy: current perspectives. Onco Targets Ther. 2022;15:783.
Article PubMed PubMed Central Google Scholar
Szabó I, et al. Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci U S A. 2008;105(39):14861–6.
Article PubMed PubMed Central Google Scholar
Ionov Y, et al. Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution. Proc Natl Acad Sci U S A. 2000;97(20):10872–7.
Article PubMed PubMed Central CAS Google Scholar
Bartok A, et al. Margatoxin is a non-selective inhibitor of human Kv1. 3 K+ channels. Toxicon. 2014;87:6–16.
Article PubMed CAS Google Scholar
Szabò I, et al. Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax-and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis. Cell Death Differ. 2011;18(3):427–38.
Erdogan A, et al. Margatoxin inhibits VEGF-induced hyperpolarization, proliferation and nitric oxide production of human endothelial cells. J Vasc Res. 2005;42(5):368–76.
Article PubMed CAS Google Scholar
Wu BM, et al. Margatoxin mitigates CCl4-induced hepatic fibrosis in mice via macrophage polarization, cytokine secretion and STAT signaling. Int J Mol Med. 2020;45(1):103–14.
Ge X, et al. Advances of non-ionic surfactant vesicles (niosomes) and their application in drug delivery. Pharmaceutics. 2019;11(2):55.
Article PubMed PubMed Central CAS Google Scholar
Bartelds R, et al. Niosomes, an alternative for liposomal delivery. PLoS ONE. 2018;13(4):e0194179.
Article PubMed PubMed Central Google Scholar
Amoabediny G, et al. Overview of preparation methods of polymeric and lipid-based (niosome, solid lipid, liposome) nanoparticles: a comprehensive review. Int J Polym Mater Polym Biomater. 2018;67(6):383–400.
Haseli S, et al. A novel pH-responsive nanoniosomal emulsion for sustained release of curcumin from a chitosan-based nanocarrier: emphasis on the concurrent improvement of loading, sustained release, and apoptosis induction. Biotechnol Prog. 2022;38(5):e3280.
Article PubMed CAS Google Scholar
Gharbavi M, et al. In vivo and in vitro biocompatibility study of novel microemulsion hybridized with bovine serum albumin as nanocarrier for drug delivery. Heliyon. 2019. https://doi.org/10.1016/j.heliyon.2019.e01858.
Article PubMed PubMed Central Google Scholar
Witika BA, et al. Current advances in specialised niosomal drug delivery: manufacture, characterization and drug delivery applications. Int J Mol Sci. 2022;23(17):9668.
Article PubMed PubMed Central CAS Google Scholar
Ruwizhi N, Aderibigbe BA. The efficacy of cholesterol-based carriers in drug delivery. Molecules. 2020;25(18):4330.
Article PubMed PubMed Central CAS Google Scholar
Moammeri A, et al. Current advances in niosomes applications for drug delivery and cancer treatment. Mater Today Bio. 2023. https://doi.org/10.1016/j.mtbio.2023.100837.
Article PubMed PubMed Central Google Scholar
Haider AJ, Al-Kinani MA, Al-Musawi S. Preparation and characterization of gold coated super paramagnetic iron nanoparticle using pulsed laser ablation in liquid method. Key Eng Mater. 2021;886:77–85.
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