Siegel RL, Giaquinto AN, et al. Cancer statistics, 2024. CA Cancer J Clin. 2024;74(1):12–49.
Zhang J, Huang Z, et al. PRMT1-mediated PARP1 methylation drives lung metastasis and chemoresistance via P65 activation in triple-negative breast cancer. Research. 2025;8:0854.
Article CAS PubMed PubMed Central Google Scholar
Smolarz B, Nowak AZ, et al. Breast cancer-epidemiology, classification, pathogenesis and treatment (review of literature). Cancers (Basel). 2022. https://doi.org/10.3390/cancers14102569.
Article PubMed PubMed Central Google Scholar
Siegel RL, Miller KD, et al. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7–33.
Xiong X, Zheng LW, et al. Breast cancer: pathogenesis and treatments. Signal Transduct Target Ther. 2025;10(1):49.
Article PubMed PubMed Central Google Scholar
Xia C, Dong X, et al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants. Chin Med J (Engl). 2022;135(5):584–90.
Article PubMed PubMed Central Google Scholar
Lei S, Zheng R, et al. Global patterns of breast cancer incidence and mortality: a population-based cancer registry data analysis from 2000 to 2020. Cancer Commun. 2021;41(11):1183–94.
Duncan W, Kerr GR. The curability of breast cancer. Br Med J. 1976;2(6039):781–3.
Article CAS PubMed PubMed Central Google Scholar
Miller KD, Nogueira L, et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019;69(5):363–85.
Fan W, Cai W, et al. Identification of seven new human MHC class I region genes around the HLA-F locus. Immunogenetics. 1996;44(2):97–103.
Article CAS PubMed Google Scholar
Aichem A, Groettrup M. The ubiquitin-like modifier FAT10 in cancer development. Int J Biochem Cell Biol. 2016;79:451–61.
Article CAS PubMed Google Scholar
Ebstein F, Lehmann A, et al. The FAT10- and ubiquitin-dependent degradation machineries exhibit common and distinct requirements for MHC class I antigen presentation. Cell Mol Life Sci. 2012;69(14):2443–54.
Article CAS PubMed Google Scholar
Mah MM, Roverato N, et al. Regulation of interferon induction by the ubiquitin-like modifier FAT10. Biomolecules. 2020. https://doi.org/10.3390/biom10060951.
Article PubMed PubMed Central Google Scholar
Zhang H, Fu L. The role of ALDH2 in tumorigenesis and tumor progression: targeting ALDH2 as a potential cancer treatment. Acta Pharm Sin B. 2021;11(6):1400–11.
Article CAS PubMed PubMed Central Google Scholar
Tanyi JL, George E. Personalized vaccination against ovarian cancer: what are the possibilities? Expert Rev Vaccines. 2018;17(11):955–8.
Article CAS PubMed PubMed Central Google Scholar
Theng SS, Wang W, et al. Disruption of FAT10-MAD2 binding inhibits tumor progression. Proc Natl Acad Sci U S A. 2014;111(49):E5282-5291.
Article CAS PubMed PubMed Central Google Scholar
Merbl Y, Refour P, et al. Profiling of ubiquitin-like modifications reveals features of mitotic control. Cell. 2013;152(5):1160–72.
Article CAS PubMed PubMed Central Google Scholar
Han T, Liu Z, et al. High expression of UBD correlates with epirubicin resistance and indicates poor prognosis in triple-negative breast cancer. Onco Targets Ther. 2015;8:1643–9.
PubMed PubMed Central Google Scholar
Chen X, Wu W, et al. Cytokines-activated nuclear IKKα-FAT10 pathway induces breast cancer tamoxifen-resistance. Sci China Life Sci. 2024;67(7):1413–26.
Article CAS PubMed Google Scholar
Xue F, Zhu L, et al. FAT10 is associated with the malignancy and drug resistance of non-small-cell lung cancer. Onco Targets Ther. 2016;9:4397–409.
Article CAS PubMed PubMed Central Google Scholar
Lukasiak S, Schiller C, et al. Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon. Oncogene. 2008;27(46):6068–74.
Article CAS PubMed Google Scholar
Liu L, Dong Z, et al. As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3β pathway. Oncogene. 2014;33(7):909–20.
Article CAS PubMed Google Scholar
Yuan R, Wang K, et al. Ubiquitin-like protein FAT10 promotes the invasion and metastasis of hepatocellular carcinoma by modifying β-catenin degradation. Cancer Res. 2014;74(18):5287–300.
Article CAS PubMed Google Scholar
Akrida I, Mulita F, et al. Epithelial to mesenchymal transition (EMT) in metaplastic breast cancer and phyllodes breast tumors. Med Oncol. 2023;41(1):20.
Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009;119(6):1420–8.
Article CAS PubMed PubMed Central Google Scholar
Pastushenko I, Brisebarre A, et al. Identification of the tumour transition States occurring during EMT. Nature. 2018;556(7702):463–8.
Article CAS PubMed Google Scholar
Nijkamp MM, Span PN, et al. Expression of E-cadherin and vimentin correlates with metastasis formation in head and neck squamous cell carcinoma patients. Radiother Oncol. 2011;99(3):344–8.
Article CAS PubMed Google Scholar
Livasy CA, Karaca G, et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol. 2006;19(2):264–71.
Article CAS PubMed Google Scholar
Grigore AD, Jolly MK, et al. Tumor Budding: The Name is EMT. Partial EMT. J Clin Med. 2016. https://doi.org/10.3390/jcm5050051.
Article PubMed PubMed Central Google Scholar
Dmello C, Sawant S, et al. Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients. PLoS One. 2017;12(2):e0172559.
Article PubMed PubMed Central Google Scholar
Zacharias M, Brcic L, et al. Bulk tumour cell migration in lung carcinomas might be more common than epithelial-mesenchymal transition and be differently regulated. BMC Cancer. 2018;18(1):717.
Article PubMed PubMed Central Google Scholar
George JT, Jolly MK, et al. Survival outcomes in cancer patients predicted by a partial EMT gene expression scoring metric. Cancer Res. 2017;77(22):6415–28.
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