Canty JM, Giglia J, Kandath D (1990) Effect of tachycardia on regional function and transmural myocardial perfusion during graded coronary pressure reduction in conscious dogs. Circulation 82:1815–1825
Canty JM Jr. (1988) Coronary pressure-function and steady-state pressure-flow relations during autoregulation in the unanesthetized dog. Circ Res 63:821–836
Canty JM Jr., Smith TP Jr. (1995) Adenosine-recruitable flow reserve is absent during myocardial ischemia in unanesthetized dogs studied in the basal state. Circ Res 76:1079–1087
Canty JM Jr., Smith TP Jr. (1995) Modulation of coronary autoregulatory responses by endothelium-derived nitric oxide. Int J Cardiol 50:207–215
Canty JM, Klocke FJ (1985) Reduced regional myocardial perfusion in the presence of pharmacologic vasodilator reserve. Circulation 71:370–377
Cho YK, Merkle H, Zhang J, Tsekos NV, Bache RJ, Ugurbil K (2001) Noninvasive measurements of transmural myocardial metabolites using 3-D 31P NMR spectroscopy. Am J Physiol Heart Circ Physiol 280:H489–H497
Article CAS PubMed Google Scholar
Duncker DJ, Bache RJ (1994) Inhibition of nitric oxide production aggravates myocardial hypoperfusion during exercise in the presence of a coronary artery stenosis. Circ Res 74:629–640
Article CAS PubMed Google Scholar
Essajee SI, Dick GM, Tucker SM, Warne CM, Figueroa CA, Beard DA, Duncker DJ, Tune JD (2025) Impairment of local metabolic coronary control involves perfusion-contraction matching not supply–demand imbalance. Basic Res Cardiol. https://doi.org/10.1007/s00395-025-01148-3
Fallavollita JA, Malm BJ, Canty JM (2003) Hibernating myocardium retains metabolic and contractile reserve despite regional reductions in flow, function, and oxygen consumption at rest. Circ Res 92:48–55. https://doi.org/10.1161/01.res.0000049104.57549.03
Article CAS PubMed Google Scholar
Galassi AR, Crea F, Araujo MI, Lammertsma AA, Pupita G, Yamamoto Y, Rechavia E, Jones T, Kaski JC, Maseri A (1993) Comparison of regional myocardial blood flow in syndrome X and one-vessel coronary artery disease. Am J Cardiol 72:134–139
Article CAS PubMed Google Scholar
Gallagher KP, Matsuzaki M, Koziol JA, Kemper WS, Ross J Jr. (1984) Regional myocardial perfusion and wall thickening during ischemia in conscious dogs. Am J Physiol 247:H727–H738
Gioia GD, Melin JA, Bruyne BD (2020) Coronary autoregulatory plateau in humans. JACC 76:1270–1271. https://doi.org/10.1016/j.jacc.2020.06.074
Gladwin MT, Crawford JH, Patel RP (2004) The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation. Free Radic Biol Med 36:707–717. https://doi.org/10.1016/j.freeradbiomed.2003.11.032
Article CAS PubMed Google Scholar
Gregg DE (1963) Effect of coronary perfusion pressure or coronary flow on oxygen usage of the myocardium. Circ Res 13:497–500. https://doi.org/10.1161/01.RES.13.6.497
Article CAS PubMed Google Scholar
Heusch G (2019) Myocardial ischemia: lack of coronary blood flow, myocardial oxygen supply-demand imbalance, or what? Am J Physiol Heart Circ Physiol 316:H1439–H1446. https://doi.org/10.1152/ajpheart.00139.2019
Article CAS PubMed PubMed Central Google Scholar
Heusch G (2021) Myocardial stunning and hibernation revisited. Nat Rev Cardiol 18:522–536. https://doi.org/10.1038/s41569-021-00506-7
Mahendiran T, Collet C, de Bruyne B (2024) Coronary-artery autoregulation with increasing stenosis. N Engl J Med 390:2030–2032. https://doi.org/10.1056/NEJMc2402216
Ostergaard L, Kristiansen SB, Angleys H, Frøkiær J, Michael Hasenkam J, Jespersen SN, Bøtker HE (2014) The role of capillary transit time heterogeneity in myocardial oxygenation and ischemic heart disease. Basic Res Cardiol 109:409. https://doi.org/10.1007/s00395-014-0409-x
Article CAS PubMed PubMed Central Google Scholar
Pantely GA, Malone SA, Rhen WS, Anselone CG, Arai A, Bristow J, Bristow JD (1990) Regeneration of myocardial phosphocreatine in pigs despite continued moderate ischemia. Circ Res 67:1481–1493
Article CAS PubMed Google Scholar
Ross J Jr (1991) Myocardial perfusion-contraction matching: implications for coronary heart disease and hibernation. Circulation 83:1076–1083
Schulz R, Guth BD, Pieper K, Martin C, Heusch G (1992) Recruitment of an inotropic reserve in moderately ischemic myocardium at the expense of metabolic recovery. A model of short-term hibernation. Circ Res 70:1282–1295. https://doi.org/10.1161/01.res.70.6.1282
Article CAS PubMed Google Scholar
Traverse JH, Melchert P, Pierpont GL, Jones B, Crampton M, Bache RJ (1999) Regulation of myocardial blood flow by oxygen consumption is maintained in the failing heart during exercise. Circ Res 84:401–408
Article CAS PubMed Google Scholar
Weiss HR, Neubauer JA, Lipp JA, Sinha AK (1978) Quantitative determination of regional oxygen consumption in the dog heart. Circ Res 42:394–401
Comments (0)