Advances in endometrial cancer screening: a comprehensive review of current methods and emerging technologies

Gu B-x, Shang X, Yan M et al (2021) Variations in incidence and mortality rates of endometrial cancer at the global, regional, and national levels, 1990-2019. Gynecol Oncol. https://doi.org/10.1016/j.ygyno.2021.01.036

Article  PubMed  Google Scholar 

Zhang S, Gong T-T, Liu F-H et al (2019) Global, regional, and national burden of endometrial cancer, 1990–2017: results from the global burden of disease study, 2017. Front Oncol 9:1440

Article  PubMed  PubMed Central  Google Scholar 

Bentivegna E, Gouy S, Maulard A et al (2016) Oncological outcomes after fertility-sparing surgery for cervical cancer: a systematic review. Lancet Oncol 17(6):e240–e253

Article  PubMed  Google Scholar 

Chhabra SA (2019) Risk factors and variations in global occurrence of endometrial cancer. J Gynaecol Womens Healthc 2:102

Google Scholar 

Lortet-Tieulent J, Ferlay J, Bray F et al (2018) International patterns and trends in endometrial cancer incidence, 1978–2013. JNCI J Natl Cancer Inst 110(4):354–361

Article  PubMed  Google Scholar 

Clarke MA, Long BJ, Morillo ADM et al (2018) Association of endometrial cancer risk with postmenopausal bleeding in women: a systematic review and meta-analysis. JAMA Intern Med 178(9):1210–1222

Article  PubMed  PubMed Central  Google Scholar 

Pakish JB, Lu KH, Sun CC et al (2016) Endometrial cancer associated symptoms: a case-control study. J Womens Health 25(11):1187–1192

Article  Google Scholar 

Braun MM, Overbeek-Wager EA, Grumbo RJ (2016) Diagnosis and management of endometrial cancer. Am Fam Physician 93(6):468–474

PubMed  Google Scholar 

Vitale SG, Buzzaccarini G, Riemma G et al (2023) Endometrial biopsy: indications, techniques and recommendations. An evidence-based guideline for clinical practice. J Gynecol Obstet Hum Reprod 52(6):102588

Article  PubMed  Google Scholar 

Westin SN, Moore K, Chon HS et al (2024) Durvalumab plus carboplatin/paclitaxel followed by maintenance durvalumab with or without olaparib as first-line treatment for advanced endometrial cancer: the phase III DUO-E trial. J Clin Oncol 42(3):283–299

Article  CAS  PubMed  Google Scholar 

Cheewakriangkrai C, Kietpeerakool C, Charoenkwan K, Pattanittum P, John D, Aue‐aungkul A, Lumbiganon P (2020) Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer. Cochrane Data System Rev 3(3):CD013253. https://doi.org/10.1002/14651858.CD013253.pub2

Article  Google Scholar 

Li C-C, Feng T-h (2016) Overview of endometrial cancer. Hu li za zhi J Nurs 63(5):5–11

Google Scholar 

Pennington M, Gentry-Maharaj A, Karpinskyj C et al (2016) Long-term secondary care costs of endometrial cancer: a prospective cohort study nested within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). PLoS ONE 11(11):e0165539

Article  PubMed  PubMed Central  Google Scholar 

Kebede N, Shah R, Shah A et al (2022) Treatment patterns and economic burden among cervical and endometrial cancer patients newly initiating systemic therapy. Future Oncol 18(8):953–964

Article  CAS  PubMed  Google Scholar 

Sanjida S, Obermair A, Gebski V et al (2021) Long-term quality of life outcomes of women treated for early-stage endometrial cancer. Int J Gynecol Cancer 31(4):530–536

Article  PubMed  Google Scholar 

Njoku K, Abiola J, Russell J et al (2020) Endometrial cancer prevention in high-risk women. Best Pract Res Clin Obstet Gynaecol 65:66–78

Article  PubMed  Google Scholar 

Baker-Rand H, Kitson SJ (2024) Recent advances in endometrial cancer prevention, early diagnosis and treatment. Cancers 16(5):1028

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cabrera S, de la Calle I, Baulies S et al (2024) Screening strategies to improve early diagnosis in endometrial cancer. J Clin Med. https://doi.org/10.3390/jcm13185445

Article  PubMed  PubMed Central  Google Scholar 

Sroczynski G, Gogollari A, Conrads-Frank A et al (2018) PMD84—cost effectiveness of endometrial cancer screening and prevention—a systematic review of economic models. Value Health. https://doi.org/10.1016/j.jval.2018.09.1533

Article  Google Scholar 

Gentry-Maharaj A, Karpinskyj C (2020) Current and future approaches to screening for endometrial cancer. Best Pract Res Clin Obstet Gynaecol. https://doi.org/10.1016/j.bpobgyn.2019.12.006

Article  PubMed  Google Scholar 

Schiemer R, Furniss D, Phang S et al (2022) Vibrational biospectroscopy: an alternative approach to endometrial cancer diagnosis and screening. Int J Mol Sci 23(9):4859. https://doi.org/10.3390/ijms23094859

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ge J, Fader AN, Dudley JC (2023) Early detection of endometrial cancer. Gynecol Oncol 174:A1–A2. https://doi.org/10.1016/j.ygyno.2023.06.010

Article  PubMed  Google Scholar 

Langer RD, Pierce JJ, O’Hanlan KA et al (1997) Transvaginal ultrasonography compared with endometrial biopsy for the detection of endometrial disease. N Engl J Med 337:1792–1798

Article  CAS  PubMed  Google Scholar 

Papadopoulos V, Tsiveriotis K, Decavalas G (2015) The Role of Ultrasound in Endometrial cancer. Int J Clin Ther Diagn. S1:0011–4. https://doi.org/10.19070/2332-2926-SI01001

Article  Google Scholar 

Fan B, Zhao Q, Zhang SH et al (2010) Assessment of transvaginal sonography combined with endometrial cytology as a mass screening method for endometrial cancer in Beijing. J Int Med Res 38:803–809

Article  CAS  PubMed  Google Scholar 

Elagwany AS (2022) 2022-RA-129-ESGO Ultrasound staging of endometrial cancer. Int J Gynecol Cancer 32:A87

Article  Google Scholar 

Billingsley C, Kenne KA, Cansino CD et al (2015) The use of transvaginal ultrasound in type II endometrial cancer. Int J Gynecol Cancer 25:858–862

Article  PubMed  Google Scholar 

Sawicki W, Śpiewankiewicz B, Stelmachów J et al (2003) The value of ultrasonography in preoperative assessment of selected prognostic factors in endometrial cancer. Eur J Gynaecol Oncol 24(3–4):293–298

CAS  PubMed  Google Scholar 

Capozzi VA, Merisio C, Rolla M et al (2020) Confounding factors of transvaginal ultrasound accuracy in endometrial cancer. J Obstet Gynaecol 41:779–784

Article  PubMed  Google Scholar 

Yang Xi, Ma Ke, Liao Q et al (2023) EP143/#483 a study evaluating liquid-based endometrial cytology test and transvaginal ultrasonography as a screening tool for endometrial cancer in 570 postmenopausal women. Int J Gynecol Cancer 33:A136. https://doi.org/10.1136/ijgc-2023-IGCS.238

Article  Google Scholar 

Mcpencow A, Erekson EA, Guess MK et al (2013) Cost-effectiveness of endometrial evaluation prior to morcellation in surgical procedures for prolapse. Am J Obstet Gynecol 209(1):22.e1–9

Article  PubMed  Google Scholar 

Bakour SH, Jones SE, O’Donovan P (2006) Ambulatory hysteroscopy: evidence-based guide to diagnosis and therapy. Best Pract Res Clin Obstet Gynaecol 20(6):953–975

Article  PubMed  Google Scholar 

Varlas V, Rhazi Y, Cloțea E et al (2021) Hysterolaparoscopy: a gold standard for diagnosing and treating infertility and benign uterine pathology. J Clin Med 10(16):3749

Article  PubMed  PubMed Central  Google Scholar 

Xia E, Yu D (2022) Diagnostic hysteroscopy. In: Xia E, Editor, Practical Manual of Hysteroscopy. Singapore: Springer Nature Singapore; pp. 73–181

Carugno J, Marbin SJ, Laganà AS et al (2021) New development on hysteroscopy for endometrial cancer diagnosis: state of the art. Minerva Med. https://doi.org/10.23736/S0026-4806.20.07123-2

Article  PubMed 

Comments (0)

No login
gif