Wasim S, Lee SY, Kim J. Complexities of prostate cancer. Int J Mol Sci. 2022;23:14257.
Article PubMed PubMed Central Google Scholar
Chang AJ, Autio KA, Roach M 3rd, Scher HI. High-risk prostate cancer-classification and therapy. Nat Rev Clin Oncol. 2014;11:308–23.
Article PubMed PubMed Central Google Scholar
Filho AM, Laversanne M, Ferlay J, Colombet M, Piñeros M, Znaor A, et al. The GLOBOCAN 2022 cancer estimates: Data sources, methods, and a snapshot of the cancer burden worldwide. Int J Cancer. 2025;156:1336–46.
Rizzo A, Santoni M, Mollica V, Fiorentino M, Brandi G, Massari F. Microbiota and prostate cancer. Semin Cancer Biol. 2022;86:1058–65.
Article CAS PubMed Google Scholar
Kennedy TAC, Ong WL, Quon H, Cheung P, Chu W, Chung H, et al. Stereotactic radiation therapy for localized prostate cancer: 10-year outcomes from three prospective trials. Int J Radiat Oncol Biol Phys. 2025;121:325–30.
Gillessen S, Bossi A, Davis ID, de Bono J, Fizazi K, James ND, et al. Management of patients with advanced prostate cancer. Part I: intermediate-/high-risk and locally advanced disease, biochemical relapse, and side effects of hormonal treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022. Eur Urol. 2023;83:267–93.
Article CAS PubMed Google Scholar
Watson PA, Arora VK, Sawyers CL. Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer. Nat Rev Cancer. 2015;15:701–11.
Article CAS PubMed PubMed Central Google Scholar
Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell. 2011;19:575–86.
Article CAS PubMed PubMed Central Google Scholar
Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, Wang S, et al. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell. 2011;19:792–804.
Article CAS PubMed PubMed Central Google Scholar
Butler DE, Marlein C, Walker HF, Frame FM, Mann VM, Simms MS, et al. Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer. Oncotarget. 2017;8:56698–713.
Article PubMed PubMed Central Google Scholar
Ravi P, Wang V, Fichorova RN, McGregor B, Wei XX, Basaria S, et al. IGF-1 axis changes with ADT and docetaxel in metastatic prostate cancer. Endocr Relat Cancer. 2023;30:e230241.
Article PubMed PubMed Central Google Scholar
Matsushita M, Fujita K, Hayashi T, Kayama H, Motooka D, Hase H, et al. Gut microbiota-derived short-chain fatty acids promote prostate cancer growth via IGF1 signaling. Cancer Res. 2021;81:4014–26.
Article CAS PubMed Google Scholar
Zhao Y, Cai C, Zhang M, Shi L, Wang J, Zhang H, et al. Ephrin-A2 promotes prostate cancer metastasis by enhancing angiogenesis and promoting EMT. J Cancer Res Clin Oncol. 2021;147:2013–23.
Article CAS PubMed PubMed Central Google Scholar
Su W, Han HH, Wang Y, Zhang B, Zhou B, Cheng Y, et al. The polycomb repressor complex 1 drives double-negative prostate cancer metastasis by coordinating stemness and immune suppression. Cancer Cell. 2019;36:139–55.e10.
Article CAS PubMed PubMed Central Google Scholar
Li N, Liu Q, Han Y, Pei S, Cheng B, Xu J, et al. ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression. Nat Commun. 2022;13:7281.
Article CAS PubMed PubMed Central Google Scholar
Yamada Y, Beltran H. The treatment landscape of metastatic prostate cancer. Cancer Lett. 2021;519:20–9.
Article CAS PubMed PubMed Central Google Scholar
Guo C, Figueiredo I, Gurel B, Neeb A, Seed G, Crespo M, et al. B7-H3 as a therapeutic target in advanced prostate cancer. Eur Urol. 2023;83:224–38.
Article CAS PubMed Google Scholar
Will M, Qin AC, Toy W, Yao Z, Rodrik-Outmezguine V, Schneider C, et al. Rapid induction of apoptosis by PI3K inhibitors is dependent upon their transient inhibition of RAS-ERK signaling. Cancer Discov. 2014;4:334–47.
Article CAS PubMed PubMed Central Google Scholar
Siech C, Rutz J, Maxeiner S, Grein T, Sonnenburg M, Tsaur I, et al. Insulin-like growth factor-1 influences prostate cancer cell growth and invasion through an integrin à3, à5, àV, and á1 dependent mechanism. Cancers. 2022;14:363.
Article PubMed PubMed Central Google Scholar
Lubik AA, Gunter JH, Hendy SC, Locke JA, Adomat HH, Thompson V, et al. Insulin increases de novo steroidogenesis in prostate cancer cells. Cancer Res. 2011;71:5754–64.
Article CAS PubMed Google Scholar
Eferl R, Wagner EF. AP-1: a double-edged sword in tumorigenesis. Nat Rev Cancer. 2003;3:859–68.
Article CAS PubMed Google Scholar
Guo XF, Zhang Z, Zheng L, Zhou YM, Wu HY, Liang CQ, et al. Developmental expression patterns of fosl genes in Xenopus tropicalis. Gene Expr Patterns. 2019;34:119056.
Article CAS PubMed Google Scholar
Huo L, Rothstein TL. Receptor-specific induction of individual AP-1 components in B lymphocytes. J Immunol. 1995;154:3300–9.
Article CAS PubMed Google Scholar
Fittall MW, Mifsud W, Pillay N, Ye H, Strobl AC, Verfaillie A, et al. Recurrent rearrangements of FOS and FOSB define osteoblastoma. Nat Commun. 2018;9:2150.
Article PubMed PubMed Central Google Scholar
Zhang H, Zhang G, Xiao M, Cui S, Jin C, Yang J, et al. Two-polarized roles of transcription factor FOSB in lung cancer progression and prognosis: dependent on p53 status. J Exp Clin Cancer Res. 2024;43:237.
Article PubMed PubMed Central Google Scholar
Zhao Y, Tang H, Kuai Y, Xu J, Sun B, Li Y. Identification of the function of FOSB in cholangiocarcinoma using bioinformatics analysis. Transl Cancer Res. 2023;12:3629–40.
Article PubMed PubMed Central Google Scholar
Wang S, Yu L, Sun X, Zhang B. Establishment and verification of potential biomarkers for cholangiocarcinoma. Exp Ther Med. 2022;24:546.
Article CAS PubMed PubMed Central Google Scholar
Yang C, Chen Y, Tang G, Shen T, Li L. Dysregulation of c-Jun (JUN) and FBJ murine osteosarcoma viral oncogene homolog B (FOSB) in obese people and their predictive values for metabolic syndrome. Endocr J. 2024;71:1157–63.
Article CAS PubMed PubMed Central Google Scholar
Skrypnik K, Suliburska J, Skrypnik D, Pilarski Ł, Reguła J, Bogdański P. The genetic basis of obesity complications. Acta Sci Pol Technol Aliment. 2017;16:83–91.
Vivian J, Rao AA, Nothaft FA, Ketchum C, Armstrong J, Novak A, et al. Toil enables reproducible, open source, big biomedical data analyses. Nat Biotechnol. 2017;35:314–6.
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