Robot-assisted versus video-assisted surgery for early functional recovery in patients with non-small-cell lung cancer: a systematic review and meta-analysis of propensity score-based matching studies

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A et al (2021) Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin 71(3):209–249

PubMed  Google Scholar 

Ganti AK, Klein AB, Cotarla I, Seal B, Chou E (2021) Update of Incidence, Prevalence, Survival, and Initial Treatment in Patients With Non-Small Cell Lung Cancer in the US. JAMA Oncol 7(12):1824–1832

Article  PubMed  PubMed Central  Google Scholar 

Ginsberg RJ, Rubinstein LV (1995) Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer. Lung Cancer Study Group. Ann Thorac Surg 60(3):615–622 discussion 22 – 3

Article  PubMed  CAS  Google Scholar 

Ettinger DS, Wood DE, Aisner DL, Akerley W, Bauman JR, Bharat A et al (2022) Non-Small Cell Lung Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 20(5):497–530

Article  PubMed  Google Scholar 

Cao C, Frick AE, Ilonen I, McElnay P, Guerrera F, Tian DH et al (2018) European questionnaire on the clinical use of video-assisted thoracoscopic surgery. Interact Cardiovasc Thorac Surg 27(3):379–383

Article  PubMed  Google Scholar 

Sihoe ADL (2020) Video-assisted thoracoscopic surgery as the gold standard for lung cancer surgery. Respirology 25(Suppl 2):49–60

Article  PubMed  Google Scholar 

da Nobrega Oliveira REN, de Andrade Pontual Peres C, Oliveira AC, Onyeji P, Kemczenski F (2024) Comparative outcomes of video-assisted thoracic surgery versus open thoracic surgery in pediatric pulmonary metastasectomy: a systematic review and meta-analysis. Pediatr Surg Int 41(1):34

Article  PubMed  Google Scholar 

D’Ambrosio PD, da Nobrega Oliveira REN, Martins MAB, Salvador I, de Andrade LG, Terra RM et al (2025) Minimally invasive vs. open chest wall resection in non-small cell lung cancer: a systematic review and meta-analysis. Transl Lung Cancer Res 14(7):2626–2635

Article  PubMed  PubMed Central  Google Scholar 

Jin R, Zheng Y, Yuan Y, Han D, Cao Y, Zhang Y et al (2022) Robotic-assisted Versus Video-assisted Thoracoscopic Lobectomy: Short-term Results of a Randomized Clinical Trial (RVlob Trial). Ann Surg 275(2):295–302

Article  PubMed  Google Scholar 

Huang J, Tian Y, Zhou QJ, Ning JW, Gu ZN, Lu PJ et al (2021) Comparison of perioperative outcomes of robotic-assisted versus video-assisted thoracoscopic right upper lobectomy in non-small cell lung cancer. Transl Lung Cancer Res 10(12):4549–4557

Article  PubMed  PubMed Central  Google Scholar 

Yang MZ, Tan ZH, Li JB, Xie CL, Sun TY, Long H et al (2023) Comparison of Short-Term Outcomes Between Robot-Assisted and Video-Assisted Segmentectomy for Small Pulmonary Nodules: A Propensity Score-Matching Study. Ann Surg Oncol 30(5):2757–2764

Article  PubMed  Google Scholar 

Zhou Q, Huang J, Pan F, Li J, Liu Y, Hou Y et al (2020) Operative outcomes and long-term survival of robotic-assisted segmentectomy for stage IA lung cancer compared with video-assisted thoracoscopic segmentectomy. Transl Lung Cancer Res 9(2):306–315

Article  PubMed  PubMed Central  Google Scholar 

Pan H, Zou N, Tian Y, Shen Y, Chen H, Zhu H et al (2024) Robotic Versus Thoracoscopic Sub-lobar Resection for Octogenarians with Clinical Stage IA Non-small Cell Lung Cancer: A Propensity Score-Matched Real-World Study. Ann Surg Oncol 31(3):1568–1580

Article  PubMed  Google Scholar 

Merritt RE, Abdel-Rasoul M, D’Souza DM, Kneuertz PJ (2022) Comparison of the long-term oncologic outcomes of robotic-assisted and video-assisted thoracoscopic lobectomy for resectable non-small cell lung carcinoma. J Robot Surg 16(6):1281–1288

Article  PubMed  Google Scholar 

Miyajima M, Maki R, Arai W, Tsuruta K, Shindo Y, Nakamura Y et al (2022) Robot-assisted vs. video-assisted thoracoscopic surgery in lung cancer. J Thorac Dis 14(6):1890–1899

Article  PubMed  PubMed Central  Google Scholar 

Tasoudis PT, Diehl JN, Merlo A, Long JM (2023) Long-term outcomes of robotic versus video-assisted pulmonary lobectomy for non-small cell lung cancer: systematic review and meta-analysis of reconstructed patient data. J Thorac Dis 15(10):5700–5713

Article  PubMed  PubMed Central  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. Int J Surg 88:105906

Article  PubMed  Google Scholar 

Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J et al (2017) AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ 358:j4008

Article  PubMed  PubMed Central  Google Scholar 

Galsky MD, Stensland KD, Moshier E, Sfakianos JP, McBride RB, Tsao CK et al (2016) Effectiveness of Adjuvant Chemotherapy for Locally Advanced Bladder Cancer. J Clin Oncol 34(8):825–832

Article  PubMed  CAS  Google Scholar 

Shi J, Luo D, Weng H, Zeng XT, Lin L, Chu H et al (2020) Optimally estimating the sample standard deviation from the five-number summary. Res Synth Methods 11(5):641–654

Article  PubMed  Google Scholar 

Shi J, Luo D, Wan X, Liu Y, Liu J, Bian Z et al (2023) Detecting the skewness of data from the five-number summary and its application in meta-analysis. Stat Methods Med Res 32(7):1338–1360

Article  PubMed  Google Scholar 

Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327(7414):557–560

Article  PubMed  PubMed Central  Google Scholar 

Sterne JA, Gavaghan D, Egger M (2000) Publication and related bias in meta-analysis: power of statistical tests and prevalence in the literature. J Clin Epidemiol 53(11):1119–1129

Article  PubMed  CAS  Google Scholar 

Wang YC, Diao HX, Xu L, Peng ZM (2025) Comparison of Early Functional Recovery Following Triportal Robot-Assisted and Uniportal Video-Assisted Segmentectomy in Patients With Early-Stage Non-Small Cell Lung Cancer: A Propensity Score-Matched Analysis. Thorac Cancer 16(5):e70041

Article  PubMed  PubMed Central  Google Scholar 

Diao H, Xu L, Li X, Wang Y, Peng Z (2024) Comparison Results of Three-Port Robot-Assisted and Uniportal Video-Assisted Lobectomy for Functional Recovery Index in the Treatment of Early Stage Non-small Cell Lung Cancer: A Propensity Score-Matched Analysis. Ann Surg Oncol 31(4):2470–2481

Article  PubMed  Google Scholar 

Zhang Y, Chen C, Hu J, Han Y, Huang M, Xiang J et al (2020) Early outcomes of robotic versus thoracoscopic segmentectomy for early-stage lung cancer: A multi-institutional propensity score-matched analysis. J Thorac Cardiovasc Surg 160(5):1363–1372

Article  PubMed  Google Scholar 

Kneuertz PJ, Cheufou DH, D’Souza DM, Mardanzai K, Abdel-Rasoul M, Theegarten D et al (2019) Propensity-score adjusted comparison of pathologic nodal upstaging by robotic, video-assisted thoracoscopic, and open lobectomy for non-small cell lung cancer. J Thorac Cardiovasc Surg. ;158(5):1457-66.e2

Hong Z, Liu Q, Li H, Cui B, Cheng T, Lu Y et al (2024) Effect of da Vinci robot versus thoracoscopic surgery on lung function and oxidative stress levels in NSCLC patients: a propensity score-matched study. Surg Endosc 38(2):706–712

Article  PubMed  Google Scholar 

Zhiqiang W, Shaohua M (2023) Perioperative outcomes of robotic-assisted versus video-assisted thoracoscopic lobectomy: A propensity score matched analysis. Thorac Cancer 14(20):1921–1931

Article  PubMed  PubMed Central  Google Scholar 

Yang S, Guo W, Chen X, Wu H, Li H (2018) Early outcomes of robotic versus uniportal video-assisted thoracic surgery for lung cancer: a propensity score-matched study. Eur J Cardiothorac Surg 53(2):348–352

Article  PubMed  Google Scholar 

von Hippel PT (2015) The heterogeneity statistic I(2) can be biased in small meta-analyses. BMC Med Res Methodol 15:35

Article  Google Scholar 

Mirza W, Javid A, Khan ME, Uneeb M, Khan A, Khan HM et al (2025) Robotic-assisted vs video-assisted thoracoscopic lobectomy for non-small cell lung cancer: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials on surgical quality, perioperative, and oncologic outcomes. J Robot Surg 19(1):651

Article  PubMed  Google Scholar 

Saeidi H, Opfermann JD, Kam M, Wei S, Leonard S, Hsieh MH et al (2022) Autonomous robotic laparoscopic surgery for intestinal anastomosis. Sci Robot 7(62):eabj2908

Article  PubMed  PubMed Central  CAS 

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