Evaluating the efficacy of photobiomodulation therapy in the management of chemotherapy-induced peripheral neuropathy: a pilot trial (NEUROLIGHT trial)

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 68(6):394–424

PubMed  Google Scholar 

Arnold M, Rutherford MJ, Bardot A, Ferlay J, Andersson TML, Myklebust TÅ et al (2019) Progress in cancer survival, mortality, and incidence in seven high-income countries 1995–2014 (ICBP SURVMARK-2): a population-based study. Lancet Oncol 20(11):1493–1505

Article  PubMed  PubMed Central  Google Scholar 

Burgess J, Ferdousi M, Gosal D, Boon C, Matsumoto K, Marshall A et al (2021) Chemotherapy-Induced Peripheral Neuropathy: Epidemiology, Pathomechanisms and Treatment. Oncol Ther 9(2):385–450

Article  PubMed  PubMed Central  Google Scholar 

Brianna LSH (2023) Chemotherapy: how to reduce its adverse effects while maintaining the potency? Med Oncol 40(3):88

Article  PubMed  CAS  Google Scholar 

Cavaletti G, Marmiroli P (2010) Chemotherapy-induced peripheral neurotoxicity. Nat Rev Neurol 6(12):657–666

Article  PubMed  Google Scholar 

Winters-Stone KM, Horak F, Jacobs PG, Trubowitz P, Dieckmann NF, Stoyles S et al (2017) Falls, Functioning, and Disability Among Women With Persistent Symptoms of Chemotherapy-Induced Peripheral Neuropathy. J Clin Oncol 35(23):2604–2612

Article  PubMed  PubMed Central  Google Scholar 

Bao T, Basal C, Seluzicki C, Li SQ, Seidman AD, Mao JJ (2016) Long-term chemotherapy-induced peripheral neuropathy among breast cancer survivors: prevalence, risk factors, and fall risk. Breast Cancer Res Treat 159(2):327–333

Article  PubMed  PubMed Central  CAS  Google Scholar 

Seretny M, Currie GL, Sena ES, Ramnarine S, Grant R, MacLeod MR et al (2014) Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis. Pain 155(12):2461–2470

Article  PubMed  Google Scholar 

Jordan B, Margulies A, Cardoso F, Cavaletti G, Haugnes HS, Jahn P et al (2020) Systemic anticancer therapy-induced peripheral and central neurotoxicity: ESMO-EONS-EANO Clinical Practice Guidelines for diagnosis, prevention, treatment and follow-up. Ann Oncol 31(10):1306–1319

Article  PubMed  CAS  Google Scholar 

Loprinzi CL, Lacchetti C, Bleeker J, Cavaletti G, Chauhan C, Hertz DL et al (2020) Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update. J Clin Oncol 38(28):3325–3348

Article  PubMed  Google Scholar 

Izycki D, Niezgoda AA, Kazmierczak M, Piorunek T, Izycka N, Karaszewska B et al (2016) Chemotherapy-induced peripheral neuropathy - diagnosis, evolution and treatment. Ginekol Pol 87(7):516–521

Article  PubMed  Google Scholar 

Rivera E, Cianfrocca M (2015) Overview of neuropathy associated with taxanes for the treatment of metastatic breast cancer. Cancer Chemother Pharmacol 75(4):659–670

Article  PubMed  PubMed Central  CAS  Google Scholar 

de Freitas LF, Hamblin MR (2016) Proposed mechanisms of photobiomodulation or low-level light therapy. IEEE J Sel Top Quantum Electron 22(3)

Abijo A, Lee CY, Huang CY, Ho PC, Tsai KJ (2023) The beneficial role of photobiomodulation in neurodegenerative diseases. Biomedicines 11(7)

de Andrade ALM, Bossini PS, De do C, Sanchez ALM, Parizotto AD (2017) NA. Effect of photobiomodulation therapy (808 nm) in the control of neuropathic pain in mice. Lasers Med Sci 32(4):865–872

Article  PubMed  Google Scholar 

Della Santa GML, Ferreira MC, Machado TPG, Oliveira MX, Santos AP (2021) Effects of Photobiomodulation Therapy (LED 630 nm) on Muscle and Nerve Histomorphometry after Axonotmesis. Photochem Photobiol 97(5):1116–1122

Article  PubMed  CAS  Google Scholar 

Lodewijckx J, Robijns J, Claes M, Evens S, Swinnen L, Lenders H et al (2022) The use of photobiomodulation therapy for the prevention of chemotherapy-induced peripheral neuropathy: a randomised, placebo-controlled pilot trial (NEUROLASER trial). Support Care Cancer 1–9

Vasquez S, Guidon M, McHugh E, Lennon O, Grogan L, Breathnach OS (2014) Chemotherapy induced peripheral neuropathy: the modified total neuropathy score in clinical practice. Ir J Med Sci 183(1):53–58

Article  PubMed  CAS  Google Scholar 

Fisher MI, Lee J, Davies CC, Geyer H, Colon G, Pfalzer L (2015) Oncology Section EDGE Task Force on Breast Cancer Outcomes: A Systematic Review of Outcome Measures for Functional Mobility. Rehabilitation Oncol 33(3):19–31

Article  Google Scholar 

Beekman E, Mesters I, Gosselink R, Klaassen MP, Hendriks EJ, Van Schayck OC et al (2014) The first reference equations for the 6-minute walk distance over a 10 m course. Thorax 69(9):867–868

Article  PubMed  Google Scholar 

Hile E, Levangie P, Ryans K, Gilchrist L (2015) Oncology Section Task Force on Breast Cancer Outcomes: Clinical Measures of Chemotherapy-induced Peripheral Neuropathy—A Systematic Review. Rehabilitation Oncol 33(3):32–41

Article  Google Scholar 

Burgess J, Ferdousi M, Gosal D, Boon C, Matsumoto K, Marshall A et al (2021) Chemotherapy-Induced Peripheral Neuropathy: Epidemiology, Pathomechanisms and Treatment. Oncol Ther 9(2):385–450

Article  PubMed  PubMed Central  Google Scholar 

Maihofner C, Diel I, Tesch H, Quandel T, Baron R (2021) Chemotherapy-induced peripheral neuropathy (CIPN): current therapies and topical treatment option with high-concentration capsaicin. Support Care Cancer 29(8):4223–4238

PubMed  PubMed Central  Google Scholar 

Argenta PA, Ballman KV, Geller MA, Carson LF, Ghebre R, Mullany SA et al (2017) The effect of photobiomodulation on chemotherapy-induced peripheral neuropathy: A randomised, sham-controlled clinical trial. Gynecol Oncol 144(1):159–166

Article  PubMed  Google Scholar 

Hsieh YL, Chou LW, Hong SF, Chang FC, Tseng SW, Huang CC et al (2016) Laser acupuncture attenuates oxaliplatin-induced peripheral neuropathy in patients with gastrointestinal cancer: a pilot prospective cohort study. Acupunct Med 34(5):398–405

Article  PubMed  Google Scholar 

McCrary JM, Goldstein D, Wyld D, Henderson R, Lewis CR, Park SB (2019) Mobility in survivors with chemotherapy-induced peripheral neuropathy and utility of the 6-min walk test. J Cancer Surviv 13(4):495–502

Article  PubMed  Google Scholar 

Li CL, Chen PY, Yang TY, Chang JT, Tang WR, Chen ML (2024) Changes in fatigue among cancer patients before, during, and after radiation therapy: A meta-analysis. Worldviews Evid Based Nurs 21(3):234–244

Article  PubMed  Google Scholar 

Cheng HL, Lopez V, Lam SC, Leung AKT, Li YC, Wong KH et al (2020) Psychometric testing of the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity (FACT/GOG-Ntx) subscale in a longitudinal study of cancer patients treated with chemotherapy. Health Qual Life Outcomes 18(1):246

Article  PubMed  PubMed Central  Google Scholar 

Teng C, Egger S, Blinman PL, Vardy JL (2022) Evaluating laser photobiomodulation for chemotherapy-induced peripheral neuropathy: a randomised phase II trial. Support Care Cancer 31(1):52

PubMed  PubMed Central  Google Scholar 

Mahfouz FM, Li T, Timmins HC, Horvath LG, Harrison M, Grimison P et al (2024) Impact of Pain on Symptom Burden in Chemotherapy-Induced Peripheral Neurotoxicity. J Natl Compr Canc Netw 22(2):108–116

Article  PubMed  Google Scholar 

Bonhof CS, Trompetter HR, Vreugdenhil G, van de Poll-Franse LV, Mols F (2020) Painful and nonpainful chemotherapy-induced peripheral neuropathy and quality of life in colorectal cancer survivors: results from the population-based PROFILES registry. Support Care Cancer 28(12):5933–5941

PubMed  PubMed Central  CAS  Google Scholar 

Timmins HC, Li T, Goldstein D, Trinh T, Mizrahi D, Harrison M et al (2022) The impact of obesity on neuropathy outcomes for paclitaxel- and oxaliplatin-treated cancer survivors. J Cancer Surviv 16(2):223–232

Article  PubMed  Google Scholar 

Nuttall FQ (2015) Body Mass Index: Obesity, BMI, and Health: A Critical Review. Nutr Today 50(3):117–128

Article  PubMed  PubMed Central  Google Scholar 

Kuriyan R (2018) Body composition techniques. Indian J Med Res 148(5):648–658

Article  PubMed  PubMed Central  CAS  Google Scholar 

Robijns J, Nair RG, Lodewijckx J, Arany P, Barasch A, Bjordal JM et al (2022) Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022. Front Oncol 12:927685

Article  PubMed 

Comments (0)

No login
gif