Abdelhamid M, Zhou C, Jung CG, Michikawa M (2022) Probiotic bifidobacterium breve MCC1274 mitigates alzheimer’s disease-related pathologies in wild-type mice. Nutrients 14(12). https://doi.org/10.3390/nu14122543

Baldacci F, Mazzucchi S, Della Vecchia A, Giampietri L, Giannini N, Koronyo-Hamaoui M et al (2020) The path to biomarker-based diagnostic criteria for the spectrum of neurodegenerative diseases. Expert Rev Mol Diagn 20(4):421–441. https://doi.org/10.1080/14737159.2020.1731306

Article  CAS  PubMed  PubMed Central  Google Scholar 

Behl T, Kyada A, Roopashree R, Nathiya D, Arya R, Kumar MR et al (2024) Epigenetic biomarkers in alzheimer’s disease: diagnostic and prognostic relevance. Ageing Res Rev 102:102556. https://doi.org/10.1016/j.arr.2024.102556

Article  CAS  PubMed  Google Scholar 

Chen Q, Yan J, Xie W, Xie W, Li M, Ye Y (2020) LncRNA LINC00641 sponges miR-497-5p to ameliorate neural injury induced by anesthesia via Up-Regulating BDNF. Front Mol Neurosci 13:95. https://doi.org/10.3389/fnmol.2020.00095

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen X, Ren G, Li Y, Chao W, Chen S, Li X et al (2022) Level of LncRNA GAS5 and hippocampal volume are associated with the progression of alzheimer’s disease. Clin Interv Aging 17:745–753. https://doi.org/10.2147/cia.S363116

Article  PubMed  PubMed Central  Google Scholar 

Devara D, Sharma B, Goyal G, Rodarte D, Kulkarni A, Tinu N et al (2025) MiRNA-501-3p and MiRNA-502-3p: A promising biomarker panel for alzheimer’s disease. Clin Translational Med 15(7):e70389. https://doi.org/10.1002/ctm2.70389

Article  CAS  Google Scholar 

Ding Y, Luan W, Shen X, Wang Z, Cao Y (2022) LncRNA BDNF-AS as CeRNA regulates the miR-9-5p/BACE1 pathway affecting neurotoxicity in alzheimer’s disease. Arch Gerontol Geriatr 99:104614. https://doi.org/10.1016/j.archger.2021.104614

Article  CAS  PubMed  Google Scholar 

Dubois B, Feldman HH, Jacova C, Dekosky ST, Barberger-Gateau P, Cummings J et al (2007) Research criteria for the diagnosis of alzheimer’s disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 6(8):734–746. https://doi.org/10.1016/s1474-4422(07)70178-3

Article  PubMed  Google Scholar 

Huang Q, Qin D, Chen C, Kang Y, Chen H, Xu M et al (2024) SHANK2-AS3: A potential biomarker for parkinson’s disease and its role in neuronal apoptosis via NF-κB signaling in SH-SY5Y cells. Heliyon 10(21):e38822. https://doi.org/10.1016/j.heliyon.2024.e38822

Article  CAS  PubMed  PubMed Central  Google Scholar 

Issa EHB, Alghazo EM, Gharaibeh R, Momani NB, Taha DZ, Jaradat RJ et al (2025) Therapeutic potential and challenges of mesenchymal stem cells in neurological disorders: A concise analysis. J Neuropathol Exp Neurol 84(8):668–679. https://doi.org/10.1093/jnen/nlaf021

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khodayi M, Khalaj-Kondori M, Hoseinpour Feizi MA, Jabarpour Bonyadi M, Talebi M (2022) Plasma LncRNA profiling identified BC200 and NEAT1 LncRNAs as potential blood-based biomarkers for late-onset alzheimer’s disease. EXCLI J 21:772–785. https://doi.org/10.17179/excli2022-4764

Article  PubMed  PubMed Central  Google Scholar 

Kuhn HG, Skau S, Nyberg J (2024) A lifetime perspective on risk factors for cognitive decline with a special focus on early events. Cereb circulation - cognition Behav 6:100217. https://doi.org/10.1016/j.cccb.2024.100217

Article  Google Scholar 

Liang W, Hou Y, Huang W, Wang Y, Jiang T, Huang X et al (2022) Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission. Sci Adv 8(33):eabn7357. https://doi.org/10.1126/sciadv.abn7357

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liang T, Wu Z, Li J, Wu S, Shi W, Wang L (2023) The emerging double-edged sword role of exosomes in alzheimer’s disease. Front Aging Neurosci 15:1209115. https://doi.org/10.3389/fnagi.2023.1209115

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liang A, Huang J, He X, Tang X, Xu X, Chen M et al (2025) MiR-501-3p/SPC24 axis affects cell proliferation, migration, invasion, apoptosis, and prognosis in renal cell carcinoma. Brazilian J Med Biol Res = Revista Brasileira De Pesquisas Medicas E Biologica 58:e13507. https://doi.org/10.1590/1414-431X2024e13507

Article  CAS  Google Scholar 

Lin Z, Qi D, Zhang Y (2025) Effects of the LINC00641/miR-323a-3p/EIF4G2 axis on behaviors and brain monoamine neurotransmitters in chronic unpredictable mild stress mice. Cell Biol Toxicol 41(1):76. https://doi.org/10.1007/s10565-025-10015-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu W, Liu X (2024) LINC00641 inhibits the development of cutaneous squamous cell carcinoma by downregulating miR-424 in A431 cells. Cancer Biother Radiopharm 39(7):532–540. https://doi.org/10.1089/cbr.2020.4325

Article  CAS  PubMed  Google Scholar 

Liu Z, Lin X, Tu Y, Zhou Y, Huang M, Fang C (2025) MALAT1 promotes microglia activation and neuronal apoptosis through via the miR-124-3p/ SGK1 axis mediating experimental autoimmune encephalomyelitis disease progression in mice. Int Immunopharmacol 152:114417. https://doi.org/10.1016/j.intimp.2025.114417

Article  CAS  PubMed  Google Scholar 

Nie F, Zhang J, Li M, Chang X, Duan H, Li H et al (2022) Transcriptome analysis of thymic tissues from Chinese Partridge Shank chickens with or without Newcastle disease virus LaSota vaccine injection via high-throughput RNA sequencing. Bioengineered 13(4):9131–9144. https://doi.org/10.1080/21655979.2021.2008737

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nong W, Bao C, Chen Y, Wei Z (2022) miR-212-3p attenuates neuroinflammation of rats with alzheimer’s disease via regulating the SP1/BACE1/NLRP3/Caspase-1 signaling pathway. Bosnian J Basic Med Sci 22(4):540–552. https://doi.org/10.17305/bjbms.2021.6723

Article  CAS  Google Scholar 

Qi W, Zhu X, Wang B, Shi Y, Dong C, Shen S et al (2025) Alzheimer’s disease digital biomarkers multidimensional landscape and AI model scoping review. NPJ Digit Med 8(1):366. https://doi.org/10.1038/s41746-025-01640-z

Article  PubMed  PubMed Central  Google Scholar 

Rogojin A, Gorbet DJ, Hawkins KM, Sergio LE (2022) Differences in resting state functional connectivity underlie visuomotor performance declines in older adults with a genetic risk (APOE ε4) for alzheimer’s disease. Front Aging Neurosci 14:1054523. https://doi.org/10.3389/fnagi.2022.1054523

Article  CAS  PubMed  PubMed Central  Google Scholar 

Toyama K, Spin JM, Tsao PS, Maruyama K, Osawa H, Mogi M et al (2023) Serum microRNA-501-3p is a potential diagnostic tool for detecting mild cognitive impairment: Ehime genome study. J Neurochem 166(6):960–971. https://doi.org/10.1111/jnc.15911

Article  CAS  PubMed  Google Scholar 

Trieu C, van Harten AC, Leeuwis AE, Exalto LG, Hooghiemstra AM, Verberk IMW et al (2024) Alzheimer’s disease and cognitive decline in patients with cardiovascular diseases along the Heart-Brain axis. J Alzheimer’s Disease: JAD 98(3):987–1000. https://doi.org/10.3233/jad-231096

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tyrakis P, Agridi C, Kourti M (2024) A comprehensive exploration of the multifaceted neuroprotective role of cannabinoids in alzheimer’s disease across a decade of research. Int J Mol Sci 25(16). https://doi.org/10.3390/ijms25168630

Wang S, Liu D, Li H, Jia X, Zhou H, Yu W et al (2025) Assessing diagnostic performance of plasma biomarkers in alzheimer’s disease versus cognitively unimpaired individuals: P-tau217 emerges as the optimal marker in Chinese cohorts. Front Aging Neurosci 17:1554805. https://doi.org/10.3389/fnagi.2025.1554805

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wen Q, Verheijen M, Wittens MMJ, Czuryło J, Engelborghs S, Hauser D et al (2022) Lead-exposure associated MiRNAs in humans and alzheimer’s disease as potential biomarkers of the disease and disease processes. Sci Rep 12(1):15966. https://doi.org/10.1038/s41598-022-20305-5

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xia P, Ma H, Chen J, Liu Y, Cui X, Wang C et al (2023) Differential expression of pyroptosis-related genes in the hippocampus of patients with alzheimer’s disease. BMC Med Genom 16(1):56. https://doi.org/10.1186/s12920-023-01479-x

Article