Abarrategui B, Mai R, Sartori I, Francione S, Pelliccia V, Cossu M, Tassi L (2021) Temporal lobe epilepsy: a never-ending story. Epilepsy & Behavior 122:108122

Article  Google Scholar 

Abdennadher M, Jacobellis S, Václavů L, Juttukonda M, Inati S, Goldstein L, van Osch MJP, Rosen B, Hua N, Theodore W (2024a) Water exchange across the blood–brain barrier and epilepsy: Review on pathophysiology and neuroimaging. In Epilepsia Oepen (Vol. 9, Issue 4). Epilepsia Open. https://doi.org/10.1002/epi4.12994

Abdennadher M, Jacobellis S, Václavů L, Juttukonda M, Inati S, Goldstein L, van Osch MJP, Rosen B, Hua N, Theodore W (2024b) Water exchange across the blood–brain barrier and epilepsy: review on pathophysiology and neuroimaging. Epilepsia Open 9(4):1123–1135. https://doi.org/10.1002/epi4.12994

Article  PubMed  PubMed Central  Google Scholar 

Abir-Awan M, Kitchen P, Salman MM, Conner MT, Conner AC, Bill RM (2019) Inhibitors of mammalian aquaporin water channels. Int J Mol Sci. https://doi.org/10.3390/ijms20071589

Article  PubMed  PubMed Central  Google Scholar 

Alvestad S, Hammer J, Hoddevik EH, Skare Ø, Sonnewald U, Amiry-Moghaddam M, Ottersen OP (2013a) Mislocalization of AQP4 precedes chronic seizures in the kainate model of temporal lobe epilepsy. Epilepsy Res 105(1–2):30–41. https://doi.org/10.1016/j.eplepsyres.2013.01.006

Article  CAS  PubMed  Google Scholar 

Alvestad S, Hammer J, Hoddevik EH, Skare Ø, Sonnewald U, Amiry-Moghaddam M, Ottersen OP (2013b) Mislocalization of AQP4 precedes chronic seizures in the kainate model of temporal lobe epilepsy. Epilepsy Res 105(1–2):30–41. https://doi.org/10.1016/j.eplepsyres.2013.01.006

Article  CAS  PubMed  Google Scholar 

Alvestad S, Hammer J, Hoddevik EH, Skare Ø, Sonnewald U, Amiry-Moghaddam M, Ottersen OP (2013c) Mislocalization of AQP4 precedes chronic seizures in the kainate model of temporal lobe epilepsy. Epilepsy Res 105(1–2):30–41. https://doi.org/10.1016/j.eplepsyres.2013.01.006

Article  CAS  PubMed  Google Scholar 

Amiry-Moghaddam M, Otsuka T, Hurn PD, Traystman RJ, Haug FM, Froehner SC, Adams ME, Neely JD, Agre P, Ottersen OP, Bhardwaj A (2003) An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proc Natl Acad Sci U S A 100(4):2106–2111. https://doi.org/10.1073/pnas.0437946100

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andersen JV, Schousboe A, Wellendorph P (2023) Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling. Essays Biochem 67(1):77–91. https://doi.org/10.1042/EBC20220208

Article  CAS  PubMed  Google Scholar 

Aronica E, Boer K, van Vliet EA, Redeker S, Baayen JC, Spliet WGM, van Rijen PC, Troost D, da Lopes Silva FH, Wadman WJ, Gorter JA (2007) Complement activation in experimental and human temporal lobe epilepsy. Neurobiol Dis 26(3):497–511. https://doi.org/10.1016/j.nbd.2007.01.015

Article  CAS  PubMed  Google Scholar 

Aulická S, Česká K, Šána J, Siegl F, Brichtová E, Ošlejšková H, Hermanová M, Hendrych M, Michu EP, Brázdil M, Slabý O, Nestrašil I (2022) Cytokine-chemokine profiles in the hippocampus of patients with mesial temporal lobe epilepsy and hippocampal sclerosis. Epilepsy Res. https://doi.org/10.1016/j.eplepsyres.2022.106858

Article  PubMed  Google Scholar 

Avoli M, Lévesque M (2021) GABAB receptors: are they missing in action in focal epilepsy research? Curr Neuropharmacol 20(9):1704–1716. https://doi.org/10.2174/1570159x19666210823102332

Article  CAS  Google Scholar 

Bai YF, Zeng C, Jia M, Xiao B (2022) Molecular mechanisms of topiramate and its clinical value in epilepsy. Seizure 98:51–56. https://doi.org/10.1016/j.seizure.2022.03.024

Article  PubMed  Google Scholar 

Balestrini S, Arzimanoglou A, Blümcke I, Scheffer IE, Wiebe S, Zelano J, Walker MC (2021) The aetiologies of epilepsy. Epileptic Disord 23(1):1–16. https://doi.org/10.1684/epd.2021.1255

Article  PubMed  Google Scholar 

Benga GH (2006) Water channel proteins: from their discovery in 1985 in Cluj-Napoca, Romania, to the 2003 nobel prize in chemistry. Cell Mol Biol 52(7):10–19. https://doi.org/10.1170/T744

Article  CAS  PubMed  Google Scholar 

Benga G (2012) The first discovered water channel protein, later called aquaporin 1: molecular characteristics, functions and medical implications. Mol Aspects Med 33(5–6):518–534. https://doi.org/10.1016/j.mam.2012.06.001

Article  CAS  PubMed  Google Scholar 

Benga G, Morariu VV (1977) Membrane defect affecting water permeability in human epilepsy [20]. Nature 265(5595):636–638. https://doi.org/10.1038/265636a0

Article  CAS  PubMed  Google Scholar 

Binder DK, Oshio K, Ma T, Verkman AS, Manley GT (2004) Increased seizure threshold in mice lacking aquaporin-4 water channels. Neuroreport 15(2):259–262. https://doi.org/10.1097/00001756-200402090-00009

Article  CAS  PubMed  Google Scholar 

Binder DK, Yao X, Verkman AS, Manley GT (2006a) Increased seizure duration in mice lacking aquaporin-4 water channels. Acta Neurochir Suppl 15(96):389–392. https://doi.org/10.1007/3-211-30714-1_80

Article  Google Scholar 

Binder DK, Yao X, Zador Z, Sick TJ, Verkman AS, Manley GT (2006b) Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia 53(6):631–636. https://doi.org/10.1002/glia.20318

Article  PubMed  Google Scholar 

Binder DK, Nagelhus EA, Ottersen OP (2012a) Aquaporin-4 and epilepsy. Glia 60(8):1203–1214. https://doi.org/10.1002/glia.22317

Article  PubMed  Google Scholar 

Binder DK, Nagelhus EA, Ottersen OP (2012b) Aquaporin-4 and epilepsy. Glia. https://doi.org/10.1002/glia.22317

Article  PubMed  Google Scholar 

Choo BKM, Shaikh Mohd. F. (2023) The Role of Neurotransmitters in Epileptogenesis: Focus on GABA and Glutamate. Handbook of Neurodegenerative Disorders. pp 1–13. https://doi.org/10.1007/978-981-19-3949-5_17-2

Chu H, Tang Y, Dong Q (2013) Protection of vascular endothelial growth factor to brain edema following intracerebral hemorrhage and its involved mechanisms: effect of Aquaporin-4. PLoS One 8(6):e66051. https://doi.org/10.1371/journal.pone.0066051

Article  CAS  PubMed  PubMed Central  Google Scholar 

Contreras-Zárate MJ, Alvarez-Eraso KLF, Jaramillo-Gómez JA, Littrell Z, Tsuji N, Ormond DR, Karam SD, Kabos P, Cittelly DM (2023) Short-term topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis. Neurooncol 25(10):1802–1814. https://doi.org/10.1093/neuonc/noad070

Article  CAS  Google Scholar 

Cunningham D, Clark K, Lord K (2022) Treatment of valproic acid overdose with meropenem in an epileptic patient. Am J Emerg Med 53:284e1. https://doi.org/10.1016/j.ajem.2021.09.033. 284.e3

Article  Google Scholar 

Das A, Wallace GC, Holmes C, McDowell ML, Smith JA, Marshall JD, Bonilha L, Edwards JC, Glazier SS, Ray SK, Banik NL (2012) Hippocampal tissue of patients with refractory Temporal lobe epilepsy is associated with astrocyte activation, inflammation, and altered expression of channels and receptors. Neuroscience 220:237–246. https://doi.org/10.1016/j.neuroscience.2012.06.002

Article  CAS  PubMed  PubMed Central  Google Scholar 

Davoudi S, Rahdar M, Hosseinmardi N, Behzadi G, Janahmadi M (2023) Chronic inhibition of astrocytic aquaporin-4 induces autistic-like behavior in control rat offspring similar to maternal exposure to valproic acid. Physiol Behav 269:114286. https://doi.org/10.1016/j.physbeh.2023.114286

Article  CAS  PubMed  Google Scholar 

Day RE, Kitchen P, Owen DS, Bland C, Marshall L, Conner AC, Bill RM, Conner MT (2014) Human aquaporins: regulators of transcellular water flow. Biochim Biophys Acta Gen Subj 1840(5):1492–1506. https://doi.org/10.1016/j.bbagen.2013.09.033

Article  CAS  Google Scholar 

Diaz-Villegas V, Pichardo-Macías LA, Juárez-Méndez S, Ignacio-Mejía I, Cárdenas-Rodríguez N, Vargas-Hernández MA, Mendoza-Torreblanca JG, Zamudio SR (2024) Changes in the dentate gyrus gene expression profile induced by Levetiracetam treatment in rats with mesial temporal lobe epilepsy. Int J Mol Sci 25(3):1690. https://doi.org/10.3390/ijms25031690

Article  CAS  PubMed  PubMed Central  Google Scholar