Allen, J., Pham, L., Bond, S. T., O’Brien, W. T., Spitz, G., Shultz, S. R., Drew, B. G., Wright, D. K., & McDonald, S. J. (2023). Acute effects of single and repeated mild traumatic brain injury on levels of neurometabolites, lipids, and mitochondrial function in male rats. Frontiers in Molecular Neuroscience, 16, 1208697.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ayata, P., Badimon, A., Strasburger, H. J., Duff, M. K., et al. (2018). Epigenetic regulation of brain region-specific microglia clearance activity. Nature Neuroscience, 21(8), 1049–1060.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bodnar, C. N., Roberts, K. N., Higgins, E. K., & Bachstetter, A. D. (2019). A systematic review of closed head injury models of mild traumatic brain injury in mice and rats. Journal of Neurotrauma., 36(11), 1683–1706.

Article  PubMed  PubMed Central  Google Scholar 

Boroda, E., Armstrong, M., Gilmore, C. S., Gentz, C., Fenske, A., Fiecas, M., Hendrickson, T., Roediger, D., Mueller, B., Kardon, R., & Lim, K. (2021). Network topology changes in chronic mild traumatic brain injury (mTBI). NeuroImage: Clinical, 31, Article 102691.

Article  PubMed  Google Scholar 

Chen, C., Hou, J., Lu, J., Zhu, Z., Yang, Y., Peng, W., & Pi, R. (2022). A novel simple traumatic brain injury mouse model. Chinese Neurosurgical Journal., 8(03), 151–159.

CAS  Google Scholar 

Chesworth, R., Gamage, R., Ullah, F., Sonego, S., Millington, C., Fernandez, A., Liang, H., Karl, T., Münch, G., Niedermayer, G., & Gyengesi, E. (2021). Spatial memory and microglia activation in a mouse model of chronic neuroinflammation and the anti-inflammatory effects of apigenin. Frontiers in Neuroscience, 15, Article 699329.

Article  PubMed  PubMed Central  Google Scholar 

Chintamen, S., Gaur, P., Vo, N., Bradshaw, E. M., Menon, V., & Kernie, S. G. (2024). Distinct microglial transcriptomic signatures within the hippocampus. PLoS ONE, 19(1), Article e0296280.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chodobski, A., Zink, B. J., & Szmydynger-Chodobska, J. (2011). Blood-brain barrier pathophysiology in traumatic brain injury. Translational Stroke Research, 2(4), 492–516.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Clark, D. P. Q., Perreau, V. M., Shultz, S. R., Brady, R. D., Lei, E., Dixit, S., Taylor, J. M., Beart, P. M., & Boon, W. C. (2019). Inflammation in traumatic brain injury: Roles for toxic A1 astrocytes and microglial-astrocytic crosstalk. Neurochemical Research, 44(6), 1410–1424.

Article  PubMed  CAS  Google Scholar 

Colville-Nash, P. R., Qureshi, S. S., Willis, D., & Willoughby, D. A. (1998). Inhibition of inducible nitric oxide synthase by peroxisome proliferator-activated receptor agonists: Correlation with induction of heme oxygenase 1. Journal of Immunology, 161(2), 978–984.

Article  CAS  Google Scholar 

Cornelius, C., Crupi, R., Calabrese, V., Graziano, A., Milone, P., Pennisi, G., & Cuzzocrea, S. (2013). Traumatic brain injury: oxidative stress and neuroprotection. Antioxidants & redox signaling, 19(8), 836–853.

Article  CAS  Google Scholar 

Corrigan, F., Mander, K. A., Leonard, A. V., & Vink, R. (2016). Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation. Journal of Neuroinflammation, 13(1), 264.

Article  PubMed  PubMed Central  Google Scholar 

Costa, B., Conti, S., Giagnoni, G., & Colleoni, M. (2002). Therapeutic effect of the endogenous fatty acid amide, palmitoylethanolamide, in rat acute inflammation: Inhibition of nitric oxide and cyclo-oxygenase systems. British Journal of Pharmacology, 137(4), 413–420.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Coupland, K. (2008). Stearidonic acid: A plant produced omega-3 PUFA and a potential alternative for marine oil fatty acids. Lipid Technology, 20, 152–154.

Article  CAS  Google Scholar 

De Felice, E., Gonçalves de Andrade, E., Golia, M. T., González Ibáñez, F., Khakpour, M., Di Castro, M. A., Garofalo, S., Di Pietro, E., Benatti, C., Brunello, N., & Tascedda, F. (2022). Microglial diversity along the hippocampal longitudinal axis impacts synaptic plasticity in adult male mice under homeostatic conditions. Journal of neuroinflammation., 19(1), 292.

Article  PubMed  PubMed Central  Google Scholar 

Egoraeva, A., Tyrtyshnaia, A., Ponomarenko, A., Ivashkevich, D., Sultanov, R., & Manzhulo, I. (2023a). Anti-inflammatory effect of polyunsaturated fatty acid N-acylethanolamines mediated by macrophage activity in vitro and in vivo. Inflammation, 46, 2306–2319.

Article  PubMed  CAS  Google Scholar 

Egoraeva, A., Tyrtyshnaia, A., Ponomarenko, A., Ivashkevich, D., Sultanov, R., & Manzhulo, I. (2023b). Anti-inflammatory effect of polyunsaturated fatty acid N-acylethanolamines mediated by macrophage activity in vitro and in vivo. Inflammation, 46(6), 2306–2319.

Article  PubMed  CAS  Google Scholar 

Gao, H. M., Liu, B., & Hong, J. S. (2023). Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons. Journal of Neuroscience, 23(15), 6181–6187.

Article  Google Scholar 

Grovola, M. R., von Reyn, C., Loane, D. J., & Cullen, D. K. (2023). Understanding microglial responses in large animal models of traumatic brain injury: An underutilized resource for preclinical and translational research. Journal of Neuroinflammation, 20(1), 67.

Article  PubMed  PubMed Central  Google Scholar 

Guil-Guerrero, J. L. (2007). Stearidonic acid (18:4n–3): Metabolism, nutritional importance, medical uses and natural sources. European Journal of Lipid Science and Technology, 109, 1226–1236.

Article  CAS  Google Scholar 

Hiskens, M. I., Li, K. M., Schneiders, A. G., & Fenning, A. S. (2023). Repetitive mild traumatic brain injury-induced neurodegeneration and inflammation is attenuated by acetyl-L-carnitine in a preclinical model. Frontiers in Pharmacology, 14, 1254382.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Huang, Y. J., Yuan, Y. J., Liu, Y. X., Zhang, M. Y., Zhang, J. G., Wang, T. C., & Zhang, M. (2018). Nitric oxide participates in the brain ischemic tolerance induced by intermittent hypobaric hypoxia in the hippocampal CA1 subfield in rats. Neurochemical research, 43(9), 1779–1790.

Article  PubMed  CAS  Google Scholar 

Iannotti, F. A., & Vitale, R. M. (2021). The endocannabinoid system and PPARs: Focus on their signalling crosstalk, action and transcriptional regulation. Cells, 10(3), 586.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Impellizzeri, D., Campolo, M., Bruschetta, G., Crupi, R., Cordaro, M., Paterniti, I., Cuzzocrea, S., & Esposito, E. (2016). Traumatic brain injury leads to development of Parkinson’s disease related pathology in mice. Frontiers in Neuroscience., 13(10), 458.

Google Scholar 

Jassam, Y. N., Izzy, S., Whalen, M., McGavern, Db., & Khy, J. E. (2017). Neuroimmunology of traumatic brain injury: Time for a paradigm shift. Neuron, 95(6), 1246–1265.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Kettenmann, H., Hanisch, U. K., Noda, M., & Verkhratsky, A. (2011). Physiology of microglia. Physiological Reviews, 91(2), 461–553.

Article  PubMed  CAS  Google Scholar 

Kim, H. Y., & Spector, A. A. (2018). N-Docosahexaenoylethanolamine: A neurotrophic and neuroprotective metabolite of docosahexaenoic acid. Molecular Aspects of Medicine, 64, 34–44.

Article  PubMed  CAS  Google Scholar 

Kraeuter, A.K., Guest, P.C., & Sarnyai, Z. The Y-maze for assessment of spatial working and reference memory in mice. InPre-clinical models: Techniques and protocols 2018 Dec 11 (pp. 105–111). New York, NY: Springer New York.

Kwon, H. S., & Koh, S. H. (2020). Neuroinflammation in neurodegenerative disorders: The roles of microglia and astrocytes. Translational Neurodegeneration, 9, 42.

Article  PubMed  PubMed Central  Google Scholar 

Li, Y., Lai, W., Zheng, C., Babu, J. R., Xue, C., Ai, Q., & Huggins, K. W. (2022). Neuroprotective effect of stearidonic acid on amyloid β-induced neurotoxicity in rat hippocampal cells. Antioxidants, 11(12), Article 2357.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Libard, S., Cerjan, D., & Alafuzoff, I. (2019). Characteristics of the tissue section that influence the staining outcome in immunohistochemistry. Histochemistry and Cell Biology., 151(1), 91–96.

Article  PubMed  CAS