Astaxanthin protects human astrocytes (HA) against 6-hydroxydopamine-induced oxidative toxicity

Wang H, Gao B, Wang L, Gong J, Zhu Z, Liu Q, Yuan H (2025) The interplay between physical exercise and autophagy signaling in brain health, neurodegenerative diseases and aging. Front Aging Neurosci 17:1579208. https://doi.org/10.3389/fnagi.2025.1579208

Article  PubMed  PubMed Central  Google Scholar 

Hu B, Wang X, Lu S, Ying X (2025) A study of bidirectional control of parkinson’s beta oscillations by basal ganglia. Chaos, Solitons & Fractals 195:116267. https://doi.org/10.1016/j.chaos.2025.116267

Article  Google Scholar 

Chang B, Jiang Y, Feng C, Li B, Mei J, Niu C (2025) Effect of purine diet on prognosis of deep brain stimulation for Parkinson’s disease. Food Sci Hum Wellness. https://doi.org/10.26599/FSHW.2024.9250066

Article  Google Scholar 

Wang L, Wang X, Deng L, Zhang H, He B, Cao W, Cui Y (2022) Pexidartinib (PLX3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders. Int Immunopharmacol 113(B):109436. https://doi.org/10.1016/j.intimp.2022.109436

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hu B, Guo Y, Zhao J, Ma X (2025) Possible regulatory mechanisms of typical and atypical absence seizures through an equivalent projection from the subthalamic nucleus to the cortex: evidence in a computational model. J Theor Biol 602:112059. https://doi.org/10.1016/j.jtbi.2025.112059

Article  CAS  PubMed  Google Scholar 

Krsek A, Baticic L (2024) Nanotechnology-driven therapeutic innovations in neurodegenerative disorders: a focus on alzheimer’s and parkinson’s disease. Future Pharmacol 4(2):352–379. https://doi.org/10.3390/futurepharmacol4020020

Article  Google Scholar 

Lan Z, Tan F, He J, Liu J, Lu M, Hu Z, Zhuo Y, Liu J, Tang X, Jiang Z (2024) Curcumin-primed olfactory mucosa-derived mesenchymal stem cells mitigate cerebral ischemia/reperfusion injury-induced neuronal panoptosis by modulating microglial polarization. Phytomedicine 129:155635. https://doi.org/10.1016/j.phymed.2024.155635

Article  CAS  PubMed  Google Scholar 

Hu E, Li Z, Li T, Yang X, Ding R, Jiang H, Su H, Cheng M, Yu Z, Li H (2023) A novel microbial and hepatic biotransformation-integrated network pharmacology strategy explores the therapeutic mechanisms of bioactive herbal products in neurological diseases: the effects of astragaloside IV on intracerebral hemorrhage as an example. Chin Med 18(1):40. https://doi.org/10.1186/s13020-023-00745-5

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qian K, Yao C, Wang Y, Yang Q, Xiang S, Pei Q, Zhu T, Liu H, Dong S (2025) Potential of ultrashort pulsed electric fields to disrupt dense structure in glioma tumors. IEEE Trans Biomed Eng 72(11):3233–3243. https://doi.org/10.1109/TBME.2025.3565520

Article  PubMed  Google Scholar 

Houldsworth A (2024) Role of oxidative stress in neurodegenerative disorders: a review of reactive oxygen species and prevention by antioxidants. Brain Commun 6(1):fcad356. https://doi.org/10.1093/braincomms/fcad356

Article  PubMed  PubMed Central  Google Scholar 

Rawani NS, Chan AW, Dursun SM, Baker GB (2024) The underlying neurobiological mechanisms of psychosis: focus on neurotransmission dysregulation, neuroinflammation, oxidative stress, and mitochondrial dysfunction. Antioxidants 13(6):709. https://doi.org/10.3390/antiox13060709

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zeng W-J, Zhang L, Cao H, Li D, Zhang H, Xia Z, Peng R (2022) A novel inflammation-related lncRNAs prognostic signature identifies linc00346 in promoting proliferation, migration, and immune infiltration of glioma. Front Immunol 13:810572. https://doi.org/10.3389/fimmu.2022.810572

Article  CAS  PubMed  PubMed Central  Google Scholar 

Duan WW, Yang LT, Liu J, Dai ZY, Wang ZY, Zhang H, Zhang X, Liang XS, Luo P, Zhang J (2024) A tgf-β signaling‐related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response. CNS Neurosci Ther 30(4):e14489. https://doi.org/10.1111/cns.14489

Article  CAS  PubMed  Google Scholar 

Huang L, Tan J, Lin P, Chen Z, Huang Q, Yao H, Jiang L, Long B, Long Y (2024) Autoimmune encephalitis followed by hemophagocytic lymph histiocytosis: a case report. Front Immunol 15:1383255. https://doi.org/10.3389/fimmu.2024.1383255

Article  CAS  PubMed  PubMed Central  Google Scholar 

Selvaraj NR, Nandan D, Nair BG, Nair VA, Venugopal P, Aradhya R (2025) Oxidative stress and redox imbalance: common mechanisms in cancer stem cells and neurodegenerative diseases. Cells 14(7):511. https://doi.org/10.3390/cells14070511

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abood RG, Abdulhussein HA, Abbas S, Majed AA, Al-Khafagi AA, Adil A, Alsalim TA (2025) Anti-breast cancer potential of new indole derivatives: synthesis, in-silico study, and cytotoxicity evaluation on MCF-7 cells. J Mol Struct 1326:141176. https://doi.org/10.1016/j.molstruc.2024.141176

Article  CAS  Google Scholar 

Mahdi ZH, Alsalim TA, Abdulhussein HA, Majed AA, Abbas S (2024) Synthesis, molecular docking, and anti-breast cancer study of 1-H-indol-3-carbohydrazide and their derivatives. Results Chem 11:101762. https://doi.org/10.1016/j.rechem.2024.101762

Article  CAS  Google Scholar 

Kadhim NJ, Hafidh RR, Kadhim SJ, Abdulamir AS (2024) Novel isolation and optimization of anti-MRSA bacteriophages using plaque-based biokinetic methods. J Emerg Med Trauma Acute Care 5:2. https://doi.org/10.5339/jemtac.2024.iscncm.2

Article  Google Scholar 

Hafidh RR, Hafidh MR, Kadhim NJ, Abdulamir AS (2024) Isolation, optimization, and redesigning of phages of methicillin-resistant staphylococcus aureus from clinical hospital isolates in baghdad. J Emerg Med Trauma Acute Care 2024(5):3. https://doi.org/10.5339/jemtac.2024.iscncm.3

Article  Google Scholar 

Alnasrawi TH, Althabet ZA, Salih GS, Al-Jassani MJ (2019) Antibacterial activity of some nanoparticles against some pathogenic bacteria that isolated from urinary tract infections patient. Int J Drug Deliv Technol 9(04):682–685. https://doi.org/10.25258/ijddt.9.4.28

Article  Google Scholar 

Watanabe H, Dijkstra JM, Nagatsu T (2024) Parkinson’s disease: cells succumbing to lifelong dopamine-related oxidative stress and other bioenergetic challenges. Int J Mol Sci 25(4):2009. https://doi.org/10.3390/ijms25042009

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rinalduzzi S, Serafini M, Capozza M, Accornero N, Missori P, Trompetto C, Fattapposta F, Currà A (2016) Stance postural strategies in patients with chronic inflammatory demyelinating polyradiculoneuropathy. PLoS One 11(3):e0151629. https://doi.org/10.1371/journal.pone.0151629

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fakhri S, Yosifova Aneva I, Farzaei MH, Sobarzo-Sánchez E (2019) The neuroprotective effects of astaxanthin: therapeutic targets and clinical perspective. Molecules 24(14):2640. https://doi.org/10.3390/molecules24142640

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mohd Shafie A, Kamarudin S, Meor Mohd Affandi M, Siran R (2025) Exploring astaxanthin: a comprehensive review on its pharmacokinetics properties and neuroprotective potential. Nutr Neurosci 28(10):1–28. https://doi.org/10.1080/1028415X.2025.2499559

Article  Google Scholar 

Prates-Rodrigues M, Schweizer BLA, de Paula Gomes C, Ribeiro ÂM, Padovan‐Neto FE, Masini D, Lopes‐Aguiar C (2025) Challenges and opportunities in exploring non‐motor symptoms in 6‐hydroxydopamine models of parkinson’s disease: a systematic review. J Neurochem 169(2):e70008. https://doi.org/10.1111/jnc.70008

Article  CAS  PubMed  PubMed Central  Google Scholar 

Głowacka P, Oszajca K, Pudlarz A, Szemraj J, Witusik-Perkowska M (2024) Postbiotics as molecules targeting cellular events of aging brain—the role in pathogenesis, prophylaxis and treatment of neurodegenerative diseases. Nutrients 16(14):2244. https://doi.org/10.3390/nu16142244

Article  CAS  PubMed  PubMed Central  Google Scholar 

Galasso C, Orefice I, Pellone P, Cirino P, Miele R, Ianora A, Brunet C, Sansone C (2018) On the neuroprotective role of astaxanthin: new perspectives? Mar Drugs 16(8):247. https://doi.org/10.3390/md16080247

Article  CAS  PubMed  PubMed Central  Google Scholar 

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