Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74(3):229–263. https://doi.org/10.3322/caac.21834
Yan Z, Wang J, Dong Q, Zhu L, Lin W, Jiang X (2022) Predictors of tumor progression of low-grade glioma in adult patients within 5 years follow-up after surgery. Front Surg 9:937556. https://doi.org/10.3389/fsurg.2022.937556
Article PubMed PubMed Central Google Scholar
Ryall S, Tabori U, Hawkins C (2020) Pediatric low-grade glioma in the era of molecular diagnostics. Acta Neuropathol Commun 8(1):30. https://doi.org/10.1186/s40478-020-00902-z
Article PubMed PubMed Central Google Scholar
Claus EB, Walsh KM, Wiencke JK, Molinaro AM, Wiemels JL, Schildkraut JM, Bondy ML, Berger M, Jenkins R, Wrensch M (2015) Survival and low-grade glioma: the emergence of genetic information. Neurosurg Focus 38(1):E6. https://doi.org/10.3171/2014.10.FOCUS12367
Article PubMed PubMed Central Google Scholar
Taylor OG, Brzozowski JS, Skelding KA (2019) Glioblastoma multiforme: an overview of emerging therapeutic targets. Front Oncol 9:963. https://doi.org/10.3389/fonc.2019.00963
Article PubMed PubMed Central Google Scholar
Ladomersky E, Scholtens DM, Kocherginsky M, Hibler EA, Bartom ET, Otto-Meyer S, Zhai L, Lauing KL, Choi J, Sosman JA, Wu JD, Zhang B, Lukas RV, Wainwright DA (2019) The coincidence between increasing age, immunosuppression, and the incidence of patients with glioblastoma. Front Pharmacol 10:200. https://doi.org/10.3389/fphar.2019.00200
Article PubMed PubMed Central CAS Google Scholar
Hanif F, Muzaffar K, Perveen K, Malhi SM, Simjee Sh U (2017) Glioblastoma multiforme: a review of its epidemiology and pathogenesis through clinical presentation and treatment. Asian Pac J Cancer Prev 18(1):3–9. https://doi.org/10.22034/APJCP.2017.18.1.3
Article PubMed PubMed Central Google Scholar
Alirezaei Z, Amouheidari A, Basirian Jahromi R, Seyyedhosseini S, Hamidi A (2025) Survival analysis of glioblastoma: a scientometric perspective. World Neurosurg 194:123476. https://doi.org/10.1016/j.wneu.2024.11.059
Zhou YS, Wang W, Chen N, Wang LC, Huang JB (2022) Research progress of anti-glioma chemotherapeutic drugs (Review). Oncol Rep 47(5). https://doi.org/10.3892/or.2022.8312
Kotecha R, Odia Y, Khosla AA, Ahluwalia MS (2023) Key clinical principles in the management of glioblastoma. JCO Oncol Pract 19(4):180–189. https://doi.org/10.1200/OP.22.00476
Haumann R, Videira JC, Kaspers GJL, van Vuurden DG, Hulleman E (2020) Overview of current drug delivery methods across the blood-brain barrier for the treatment of primary brain tumors. CNS Drugs 34(11):1121–1131. https://doi.org/10.1007/s40263-020-00766-w
Article PubMed PubMed Central Google Scholar
Wu W, Klockow JL, Zhang M, Lafortune F, Chang E, Jin L, Wu Y, Daldrup-Link HE (2021) Glioblastoma multiforme (GBM): an overview of current therapies and mechanisms of resistance. Pharmacol Res 171:105780. https://doi.org/10.1016/j.phrs.2021.105780
Article PubMed PubMed Central CAS Google Scholar
Robey RW, Pluchino KM, Hall MD, Fojo AT, Bates SE, Gottesman MM (2018) Revisiting the role of ABC transporters in multidrug-resistant cancer. Nat Rev Cancer 18(7):452–464. https://doi.org/10.1038/s41568-018-0005-8
Article PubMed PubMed Central CAS Google Scholar
Agarwal S, Sane R, Ohlfest JR, Elmquist WF (2011) The role of the blood-brain barrier and the efflux transporters P-glycoprotein and breast cancer resistance protein in the distribution of a novel tyrosine kinase inhibitor in brain. J Pharmacol Exp Ther 336(2):827–835
Phon BWS, Chelliah SS, Osman DE, Bhuvanendran S, Radhakrishnan AK, Kamarudin MNA (2025) Revisiting ABC transporters and their clinical significance in glioblastoma. Pharmaceuticals (Basel) 18(1):102. https://doi.org/10.3390/ph18010102
Article PubMed PubMed Central CAS Google Scholar
Majchrzak-Celińska A, Sidhu A, Miechowicz I, Nowak W, Barciszewska AM (2022) ABCB1 is frequently methylated in higher-grade gliomas and May serve as a diagnostic biomarker of more aggressive tumors. J Clin Med 11(19). https://doi.org/10.3390/jcm11195655
Dréan A, Rosenberg S, Lejeune FX, Goli L, Nadaradjane AA, Guehennec J, Schmitt C, Verreault M, Bielle F, Mokhtari K, Sanson M, Carpentier A, Delattre JY, Idbaih A (2018) ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma. J Neurooncol 138(3):479–486. https://doi.org/10.1007/s11060-018-2819-3
Article PubMed CAS Google Scholar
Oberstadt MC, Bien-Möller S, Weitmann K, Herzog S, Hentschel K, Rimmbach C, Vogelgesang S, Balz E, Fink M, Michael H, Zeden JP, Bruckmüller H, Werk AN, Cascorbi I, Hoffmann W, Rosskopf D, Schroeder HW, Kroemer HK (2013) Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme. BMC Cancer 13:617. https://doi.org/10.1186/1471-2407-13-617
Article PubMed PubMed Central CAS Google Scholar
Roy LO, Lemelin M, Blanchette M, Poirier MB, Aldakhil S, Fortin D (2022) Expression of ABCB1, ABCC1 and 3 and ABCG2 in glioblastoma and their relevance in relation to clinical survival surrogates. J Neurooncol 160(3):601–609. https://doi.org/10.1007/s11060-022-04179-1
Article PubMed CAS Google Scholar
Chen Z, Zhang Y, Chen Y, Lin W, Zhang Y, Cai G, Sun X, Zheng K, He J, Ai T, Wang J, Zhao L, Ke Y (2022) Prrx1 promotes resistance to Temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma. Am J Cancer Res 12(8):3892–3912 PMID: 36119823
PubMed PubMed Central CAS Google Scholar
Hanif F, Perveen K, Malhi SM, Jawed H, Simjee SU (2018) Verapamil potentiates anti-glioblastoma efficacy of Temozolomide by modulating apoptotic signaling. Toxicol In Vitro 52:306–313. https://doi.org/10.1016/j.tiv.2018.07.001
Article PubMed CAS Google Scholar
Abe T, Koike K, Ohga T, Kubo T, Wada M, Kohno K, Mori T, Hidaka K, Kuwano M (1995) Chemosensitisation of spontaneous multidrug resistance by a 1,4-dihydropyridine analogue and verapamil in human glioma cell lines overexpressing MRP or MDR1. Br J Cancer 72(2):418–423. https://doi.org/10.1038/bjc.1995.348
Article PubMed PubMed Central CAS Google Scholar
Wu CP, Calcagno AM, Ambudkar SV (2008) Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: evaluation of current strategies. Curr Mol Pharmacol 1(2):93–105. https://doi.org/10.2174/1874467210801020093
Article PubMed PubMed Central CAS Google Scholar
Benson AB, Trump DL, Koeller JM, Egorin MI, Olman EA, Witte RS, Davis TE, Tormey DC (1985) Phase I study of vinblastine and verapamil given by concurrent Iv infusion. Cancer Treat Rep 69:795–799 PMID: 4016789
Lee JH, Choi S, Lee Y, Lee HJ, Kim KH, Ahn KS, Bae H, Lee HJ, Lee EO, Ahn KS, Ryu SY, Lü J, Kim SH (2010) Herbal compound Farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades. Mol Cancer Ther 9(2):389–399. https://doi.org/10.1158/1535-7163.MCT-09-0775
Article PubMed CAS Google Scholar
Valiahdi SM, Iranshahi M, Sahebkar A (2013) Cytotoxic activities of phytochemicals from Ferula species. DARU J Pharm Sci 21(1):39. https://doi.org/10.1186/2008-2231-21-39
Aas Z, Babaei E, Hosseinpour Feizi MA, Dehghan G (2015) Anti-proliferative and apoptotic effects of dendrosomal Farnesiferol C on gastric cancer cells. Asian Pac J Cancer Prev 16(13):5325–5329. https://doi.org/10.7314/apjcp.2015.16.13.5325
Jung JH, Kim MJ, Lee H, Lee J, Kim J, Lee HJ, Shin EA, Kim YH, Kim B, Shim BS, Kim SH (2016) Farnesiferol c induces apoptosis via regulation of L11 and c-Myc with combinational potential with anticancer drugs in non-small-cell lung cancers. Sci Rep 6:26844. https://doi.org/10.1038/srep26844
Article PubMed PubMed Central CAS Google Scholar
Tanzadehpanah H, Mahaki H, Samadi P, Karimi J, Moghadam NH, Salehzadeh S, Dastan D, Saidijam M (2019) Anticancer activity, calf thymus DNA and human serum albumin binding properties of Farnesiferol C from ferula pseudalliacea. J Biomol Struct Dyn 37(11):2789–2800. https://doi.org/10.1080/07391102.2018.1497543
Comments (0)