Lapehn S, Paquette AG. The placental epigenome as a molecular link between prenatal exposures and fetal health outcomes through the dohad hypothesis. Curr Environ Health Rep. 2022;9(3):490–501.
PubMed
PubMed Central
Google Scholar
Tong Y, Zhang S, Riddle S, Song R, Yue D. Circular RNAs in the origin of developmental lung disease: promising diagnostic and therapeutic biomarkers. Biomolecules. 2023;13(3):533.
CAS
PubMed
PubMed Central
Google Scholar
GBD Chronic Respiratory Disease Collaborators. Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: A systematic analysis for the global burden of disease study 2017. Lancet Respir Med. 2020;8(6):585–96.
Google Scholar
Labaki WW, Han MK. Chronic respiratory diseases: A global view. Lancet Respir Med. 2020;8(6):531–3.
PubMed
PubMed Central
Google Scholar
Varghese NP, Austin ED, Galambos C, Mullen MP, Yung D, Guillerman RP, et al. An interdisciplinary consensus approach to pulmonary hypertension in developmental lung disease. Eur Respir J. 2024;64(3):2400639.
CAS
PubMed
PubMed Central
Google Scholar
Giuranno L, Piepers JAF, Korsten E, Borman R, van de Kamp G, De Ruysscher D, et al. Enhanced radiation sensitivity, decreased DNA damage repair, and differentiation defects in airway stem cells derived from patients with chronic obstructive pulmonary disease. Stem Cells Transl Med. 2024;13(9):927–39.
CAS
PubMed
PubMed Central
Google Scholar
Allbright K, Villandre J, Crotty Alexander LE, Zhang M, Benam KH, Evankovich J, et al. The paradox of the safer cigarette: Understanding the pulmonary effects of electronic cigarettes. Eur Respir J. 2024;63(6):2301494.
CAS
PubMed
PubMed Central
Google Scholar
Carusillo A, Mussolino C. DNA damage: from threat to treatment. Cells. 2020;9(7):1665.
CAS
PubMed
PubMed Central
Google Scholar
Baxter JS, Zatreanu D, Pettitt SJ, Lord CJ. Resistance to DNA repair inhibitors in cancer. Mol Oncol. 2022;16(21):3811–27.
CAS
PubMed
PubMed Central
Google Scholar
Zhao Y, Simon M, Seluanov A, Gorbunova V. DNA damage and repair in age-related inflammation. Nat Rev Immunol. 2023;23(2):75–89.
CAS
PubMed
Google Scholar
Ovejero-Sánchez M, González-Sarmiento R, Herrero AB. DNA damage response alterations in ovarian cancer: from molecular mechanisms to therapeutic opportunities. Cancers. 2023;15(2):448.
PubMed
PubMed Central
Google Scholar
Sáez GT. DNA injury and repair systems. Int J Mol Sci. 2018;19(7):1902.
PubMed
PubMed Central
Google Scholar
Oksenych V, Kainov DE. DNA damage response. Biomolecules. 2021;11(1):123.
CAS
PubMed
PubMed Central
Google Scholar
Rahman S, Canny MD, Buschmann TA, Latham MP. A survey of reported disease-related mutations in the MRE11-RAD50-NBS1 complex. Cells. 2020;9(7):1678.
CAS
PubMed
PubMed Central
Google Scholar
McCarthy-Leo C, Darwiche F, Tainsky MA. DNA repair mechanisms, protein interactions and therapeutic targeting of the MRN complex. Cancers. 2022;14(21):5278.
CAS
PubMed
PubMed Central
Google Scholar
Wojtaszek JL, Williams RS. The ends in sight: Mre11-Rad50-Nbs1 complex structures come into focus. Mol Cell. 2023;83(2):160–2.
CAS
PubMed
Google Scholar
Syed A, Tainer JA. The MRE11-RAD50-NBS1 complex conducts the orchestration of damage signaling and outcomes to stress in DNA replication and repair. Ann Rev Biochem. 2018;87(1):263–94.
CAS
PubMed
Google Scholar
Qiu S, Huang J. MRN complex is an essential effector of DNA damage repair. J Zhejiang Univ Sci B. 2021;22(1):31–7.
CAS
PubMed
PubMed Central
Google Scholar
Tatebe H, Lim CT, Konno H, Shiozaki K, Shinohara A, Uchihashi T, et al. Rad50 zinc Hook functions as a constitutive dimerization module interchangeable with SMC hinge. Nat Commun. 2020;11(1):370.
CAS
PubMed
PubMed Central
Google Scholar
Vertemara J, Tisi R. Dynamic properties of the DNA damage response Mre11/Rad50 complex. Int J Mol Sci. 2023;24(15):12377.
CAS
PubMed
PubMed Central
Google Scholar
Zhang B, Tang Z, Li L, Lu LY. NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis. Cell Death Differ. 2020;27(7):2176–90.
CAS
PubMed
PubMed Central
Google Scholar
Chen H, Li Y, Li H, Chen X, Fu H, Mao D, et al. NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance. Nature. 2024;631(8021):663–9.
CAS
PubMed
PubMed Central
Google Scholar
Bian L, Meng Y, Zhang M, Li D. MRE11-RAD50-NBS1 complex alterations and DNA damage response: implications for cancer treatment. Mol Cancer. 2019;18(1):169.
CAS
PubMed
PubMed Central
Google Scholar
Deng S, Vlatkovic T, Li M, Zhan T, Veldwijk MR, Herskind C. Targeting the DNA damage response and DNA repair pathways to enhance radiosensitivity in colorectal cancer. Cancers. 2022;14(19):4874.
CAS
PubMed
PubMed Central
Google Scholar
Jin MH, Oh DY. ATM in DNA repair in cancer. Pharmacol Ther. 2019;203:107391.
CAS
PubMed
Google Scholar
Priya B, Ravi S, Kirubakaran S. Targeting ATM and ATR for cancer therapeutics: inhibitors in clinic. Drug Discov Today. 2023;28(8):103662.
CAS
PubMed
Google Scholar
Williams RM, Zhang X. Roles of ATM and ATR in DNA double strand breaks and replication stress. Prog Biophys Mol Biol. 2021;163:109–19.
CAS
PubMed
Google Scholar
Tang Q, Wang X, Wang H, Zhong L, Zou D. Advances in ATM, ATR, WEE1, and CHK1/2 inhibitors in the treatment of PARP inhibitor-resistant ovarian cancer. Cancer Biol Med. 2024;20(12):915–21.
PubMed
PubMed Central
Google Scholar
Liu MY, Lin KR, Chien YL, Yang BZ, Tsui LY, Chu HC, et al. ATR phosphorylates DHX9 at Serine 321 to suppress R-loop accumulation upon genotoxic stress. Nucleic Acids Res. 2024;52(1):204–22.
CAS
PubMed
Google Scholar
Saxena S, Zou L. Hallmarks of DNA replication stress. Mol Cell. 2022;82(12):2298–314.
CAS
PubMed
PubMed Central
Google Scholar
Lee JH. Targeting the ATM pathway in cancer: opportunities, challenges and personalized therapeutic strategies. Cancer Treat Rev. 2024;129:102808.
CAS
PubMed
Google Scholar
Knoblochova L, Duricek T, Vaskovicova M, Zorzompokou C, Rayova D, Ferencova I, et al. CHK1-CDC25A-CDK1 regulate cell cycle progression and protect genome integrity in early mouse embryos. EMBO Rep. 2023;24(10):e56530.
CAS
PubMed
PubMed Central
Google Scholar
Shibata A, Jeggo PA. ATM’s role in the repair of DNA double-strand breaks. Genes. 2021;12(9):1370.
CAS
PubMed
PubMed Central
Google Scholar
Feng YY, Liu JF, Xue Y, Liu D, Wu XZ. Network Pharmacology based Elucidation of molecular mechanisms of Laoke formula for treatment of advanced non-small cell lung cancer. Chin J Integr Med. 2024;30(11):984–92.
CAS
PubMed
Google Scholar
Karakostis K, Malbert-Colas L, Thermou A, Vojtesek B, Fåhraeus R. The DNA damage sensor ATM kinase interacts with the p53 mRNA and guides the DNA damage response pathway. Mol Cancer. 2024;23(1):21.
CAS
PubMed
PubMed Central
Google Scholar
Mirman Z, de Lange T. 53BP1: A DSB escort. Genes Dev. 2020;34(1–2):7–23.
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