Bunker CB, Shim TN. Male genital lichen sclerosus. Indian J Dermatol. 2015 Mar-Apr;60(2):111–7.
Edmonds EV, Hunt S, Hawkins D, Dinneen M, Francis N, Bunker CB. Clinical parameters in male genital lichen sclerosus: a case series of 329 patients. J Eur Acad Dermatol Venereol. 2012;26(6):730–7.
Kantere D, Löwhagen GB, Alvengren G, Månesköld A, Gillstedt M, Tunbäck P. The clinical spectrum of lichen sclerosus in male patients - a retrospective study. Acta Derm Venereol. 2014;94(5):542–6.
Hu N, Zou Y, Deng X, Zhang L, Zhai Z, Yin R. Photodynamic therapy for male genital lichen sclerosus with urethral stricture-Case report. Photodiagnosis Photodyn Ther. 2024;45:103947.
Kwok M, Shugg N, Siriwardana A, Calopedos R, Richards K, Bandi S, Hempenstall J, Rashid P, Desai D. Prevalence and sequelae of penile lichen sclerosus in males presenting for circumcision in regional australia: a multicentre retrospective cohort study. Transl Androl Urol. 2022;11(6):780–5.
Fergus KB, Lee AW, Baradaran N, Cohen AJ, Stohr BA, Erickson BA, Mmonu NA, Breyer BN. Pathophysiology, clinical manifestations, and treatment of lichen sclerosus: A systematic review. Urology. 2020;135:11–9.
Mora EMM, Champer MI, Huang W, Campagnola PJ, Grimes MD. Collagen is more abundant and structurally altered in lichen sclerosus. Urology. 2023;173:192–7.
Kravvas G, Shim TN, Doiron PR, Freeman A, Jameson C, Minhas S, Muneer A, Bunker CB. The diagnosis and management of male genital lichen sclerosus: a retrospective review of 301 patients. J Eur Acad Dermatol Venereol. 2018;32(1):91–5.
Panou E, Panagou E, Foley C, Kravvas G, Watchorn R, Alnajjar H, Muneer A, Bunker CB. Male genital lichen sclerosus associated with urological interventions and microincontinence: a case series of 21 patients. Clin Exp Dermatol. 2022;47(1):107–9.
Del Papa J, Pucchio AC, Schneider M, Wang A. Perineural inflammation as a novel feature in lichen sclerosus: A case series of histologic and clinical features. Am J Dermatopathol. 2024;46(5):287–91.
Leoni E, Kempf W, Cerroni L. Lichen sclerosus et atrophicus with histopathologic features mimicking mycosis fungoides: A large series of cases comparing genital with extragenital lichen sclerosus. Am J Surg Pathol. 2022;46(1):83–8.
Vyas A. Genital lichen sclerosus and its mimics. Obstet Gynecol Clin North Am. 2017;44(3):389–406.
Czajkowski M, Wierzbicki P, Kotulak-Chrząszcz A, Czajkowska K, Bolcewicz M, Kłącz J, Kreft K, Lewandowska A, Nedoszytko B, Sokołowska-Wojdyło M, Kmieć Z, Kalinowski L, Nowicki RJ, Matuszewski M. The role of occlusion and micro-incontinence in the pathogenesis of penile lichen sclerosus: an observational study of pro-inflammatory cytokines’ gene expression. Int Urol Nephrol. 2022;54(4):763–72.
Kravvas G, Muneer A, Watchorn RE, Castiglione F, Haider A, Freeman A, Hadway P, Alnajjar H, Lynch M, Bunker CB. Male genital lichen sclerosus, microincontinence and occlusion: mapping the disease across the prepuce. Clin Exp Dermatol. 2022;47(6):1124–30.
Krapf JM, Mitchell L, Holton MA, Goldstein AT. Vulvar lichen sclerosus: current perspectives. Int J Womens Health. 2020;12:11–20.
Scrimin F, Rustja S, Radillo O, Volpe C, Abrami R, Guaschino S. Vulvar lichen sclerosus: an Immunologic study. Obstet Gynecol. 2000;95(1):147–50.
Attili VR, Attili SK. Clinical and histopathological spectrum of genital lichen sclerosus in 133 cases: focus on the diagnosis of pre-sclerotic disease. Indian J Dermatol Venereol Leprol. 2022 Nov-Dec;88(6):774–80.
Lansdorp CA, van den Hondel KE, Korfage IJ, van Gestel MJ, van der Meijden WI. Quality of life in Dutch women with lichen sclerosus. Br J Dermatol. 2013;168(4):787–93.
Kizer WS, Prarie T, Morey AF. Balanitis xerotica obliterans: epidemiologic distribution in an equal access health care system. South Med J. 2003;96(1):9–11.
Leibovitz A, Kaplun VV, Saposhnicov N, Habot B. Vulvovaginal examinations in elderly nursing home women residents. Arch Gerontol Geriatr. 2000;31(1):1–4.
Powell JJ, Wojnarowska F. Lichen sclerosus. Lancet. 1999;353(9166):1777–83.
Oyama N, Hasegawa M. Lichen sclerosus: A current landscape of autoimmune and genetic interplay. Diagnostics (Basel). 2022;12(12):3070.
Hao Y, Stuart T, Kowalski MH, Choudhary S, Hoffman P, Hartman A, Srivastava A, Molla G, Madad S, Fernandez-Granda C, Satija R. Dictionary learning for integrative, multimodal and scalable single-cell analysis. Nat Biotechnol. 2024;42(2):293–304.
Hu C, Li T, Xu Y, Zhang X, Li F, Bai J, Chen J, Jiang W, Yang K, Ou Q, Li X, Wang P, Zhang Y. CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data. Nucleic Acids Res. 2023;51(D1):D870–6.
Jin S, Guerrero-Juarez CF, Zhang L, Chang I, Ramos R, Kuan CH, Myung P, Plikus MV, Nie Q. Inference and analysis of cell-cell communication using cellchat. Nat Commun. 2021;12(1):1088.
Wu T, Hu E, Xu S, Chen M, Guo P, Dai Z, Feng T, Zhou L, Tang W, Zhan L, Fu X, Liu S, Bo X, Yu G. ClusterProfiler 4.0: A universal enrichment tool for interpreting omics data. Innov (Camb). 2021;2(3):100141.
Trapnell C, Cacchiarelli D, Grimsby J, Pokharel P, Li S, Morse M, Lennon NJ, Livak KJ, Mikkelsen TS, Rinn JL. The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells. Nat Biotechnol. 2014;32(4):381–6.
Qiu X, Mao Q, Tang Y, Wang L, Chawla R, Pliner HA, Trapnell C. Reversed graph embedding resolves complex single-cell trajectories. Nat Methods. 2017;14(10):979–82.
Cao J, Spielmann M, Qiu X, Huang X, Ibrahim DM, Hill AJ, Zhang F, Mundlos S, Christiansen L, Steemers FJ, Trapnell C, Shendure J. The single-cell transcriptional landscape of mammalian organogenesis. Nature. 2019;566(7745):496–502.
Traag VA, Waltman L, van Eck NJ. From Louvain to leiden: guaranteeing well-connected communities. Sci Rep. 2019;9(1):5233.
Levine JH, Simonds EF, Bendall SC, Davis KL, Amir el-AD, Tadmor MD, Litvin O, Fienberg HG, Jager A, Zunder ER, Finck R, Gedman AL, Radtke I, Downing JR. Pe’er D, Nolan GP. Data-Driven phenotypic dissection of AML reveals Progenitor-like cells that correlate with prognosis. Cell. 2015;162(1):184–97.
Haghverdi L, Lun ATL, Morgan MD, Marioni JC. Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors. Nat Biotechnol. 2018;36(5):421–7.
McInnes L, Healy J, Melville JUMAP. Uniform manifold approximation and projection for dimension reduction. Preprint at https://doi.org/10.48550/arXiv.1802.03426
Võsa U, Claringbould A, Westra HJ, Bonder MJ, Deelen P, Zeng B, Kirsten H, Saha A, Kreuzhuber R, Yazar S, Brugge H, Oelen R, de Vries DH, van der Wijst MGP, Kasela S, Pervjakova N, Alves I, Favé MJ, Agbessi M, Christiansen MW, Jansen R, Seppälä I, Tong L, Teumer A, Schramm K, Hemani G, Verlouw J, Yaghootkar H, Sönmez Flitman R, Brown A, Kukushkina V, Kalnapenkis A, Rüeger S, Porcu E, Kronberg J, Kettunen J, Lee B, Zhang F, Qi T, Hernandez JA, Arindrarto W, Beutner F; BIOS Consortium; i2QTL Consortium; Dmitrieva J, Elansary M, Fairfax BP, Georges M, Heijmans BT, Hewitt AW, Kähönen M, Kim Y, Knight JC, Kovacs P, Krohn K, Li S, Loeffler M, Marigorta UM, Mei H, Momozawa Y, Müller-Nurasyid M, Nauck M, Nivard MG, Penninx BWJH, Pritchard JK, Raitakari OT, Rotzschke O, Slagboom EP, Stehouwer CDA, Stumvoll M, Sullivan P,'t Hoen PAC, Thiery J, Tönjes A, van Dongen J, van Iterson M, Veldink JH, Völker U, Warmerdam R, Wijmenga C, Swertz M, Andiappan A, Montgomery GW, Ripatti S, Perola M, Kutalik Z, Dermitzakis E, Bergmann S, Frayling T, van Meurs J, Prokisch H, Ahsan H, Pierce BL, Lehtimäki T, Boomsma DI, Psaty BM, Gharib SA, Awadalla P, Milani L, Ouwehand WH, Downes K, Stegle O, Battle A, Visscher PM, Yang J, Scholz M, Powell J, Gibson G, Esko T, Franke L. Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nat Genet. 2021;53(9):1300–10.
Kurki MI, Karjalainen J, Palta P, Sipilä TP, Kristiansson K, Donner KM, Reeve MP, Laivuori H, Aavikko M, Kaunisto MA, Loukola A, Lahtela E, Mattsson H, Laiho P, Della Briotta Parolo P, Lehisto AA, Kanai M, Mars N, Rämö J, Kiiskinen T, Heyne HO, Veerapen K, Rüeger S, Lemmelä S, Zhou W, Ruotsalainen S, Pärn K, Hiekkalinna T, Koskelainen S, Paajanen T, Llorens V, Gracia-Tabuenca J, Siirtola H, Reis K, Elnahas AG, Sun B, Foley CN, Aalto-Setälä K, Alasoo K, Arvas M, Auro K, Biswas S, Bizaki-Vallaskangas A, Carpen O, Chen CY, Dada OA, Ding Z, Ehm MG, Eklund K, Färkkilä M, Finucane H, Ganna A, Ghazal A, Graham RR, Green EM, Hakanen A, Hautalahti M, Hedman ÅK, Hiltunen M, Hinttala R, Hovatta I, Hu X, Huertas-Vazquez A, Huilaja L, Hunkapiller J, Jacob H, Jensen JN, Joensuu H, John S, Julkunen V, Jung M, Junttila J, Kaarniranta K, Kähönen M, Kajanne R, Kallio L, Kälviäinen R, Kaprio J; FinnGen; Kerimov N, Kettunen J, Kilpeläinen E, Kilpi T, Klinger K, Kosma VM, Kuopio T, Kurra V, Laisk T, Laukkanen J, Lawless N, Liu A, Longerich S, Mägi R, Mäkelä J, Mäkitie A, Malarstig A, Mannermaa A, Maranville J, Matakidou A, Meretoja T, Mozaffari SV, Niemi MEK, Niemi M, Niiranen T, O Donnell CJ, Obeidat ME, Okafo G, Ollila HM, Palomäki A, Palotie T, Partanen J, Paul DS, Pelkonen M, Pendergrass RK, Petrovski S, Pitkäranta A, Platt A, Pulford D, Punkka E, Pussinen P, Raghavan N, Rahimov F, Rajpal D, Renaud NA, Riley-Gillis B, Rodosthenous R, Saarentaus E, Salminen A, Salminen E, Salomaa V, Schleutker J, Serpi R, Shen HY, Siegel R, Silander K, Siltanen S, Soini S, Soininen H, Sul JH, Tachmazidou I, Tasanen K, Tienari P, Toppila-Salmi S, Tukiainen T, Tuomi T, Turunen JA, Ulirsch JC, Vaura F, Virolainen P, Waring J, Waterworth D, Yang R, Nelis M, Reigo A, Metspalu A, Milani L, Esko T, Fox C, Havulinna AS, Perola M, Ripatti S, Jalanko A, Laitinen T, Mäkelä TP, Plenge R, McCarthy M, Runz H, Daly MJ, Palotie A. FinnGen provides genetic insights from a well-phenotyped isolated population. Nature. 2023;613(7944):508–18.
Lin L, Ma Y, Li Z, Liu L, Hu Q, Zhou L. Genetic susceptibility of urolithiasis: comprehensive results from genome-wide analysis. World J Urol. 2024;42(1):230.
Lin L, Tang Y, Ning K, Li X, Hu X. Investigating the causal associations between metabolic biomarkers and the risk of kidney cancer. Commun Biol. 2024;7(1):398.
Lin L, Ning K, Xiang L, Peng L, Li X. SGLT2 Inhibition and three urological cancers: Up-to-date results. Diabetes Metab Res Rev. 2024;40(3):e3797.
Lin L, Wang W, Xiao K, Guo X, Zhou L. Genetically elevated bioavailable testosterone level was associated with the occurrence of benign prostatic hyperplasia. J Endocrinol Invest. 2023;46(10):2095–102.
Lin L, Li Z, Chen K, Shao Y, Li X. Uncovering somatic genetic drivers in prostate cancer through comprehensive genome-wide analysis. Geroscience. 2025;47(3):5039–56.
Zeng X, Li Z, Lin L, Wei X. Assessment of glycemic susceptibility across multiple urological and reproductive disorders. Diabetol Metab Syndr. 2024;16(1):162.
Zhu Z, Zhang F, Hu H, Bakshi A, Robinson MR, Powell JE, Montgomery GW, Goddard ME, Wray NR, Visscher PM, Yang J. Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nat Genet. 2016;48(5):481–7.
Bankhead P, Loughrey MB, Fernández JA, Dombrowski Y, McArt DG, Dunne PD, McQuaid S, Gray RT, Murray LJ, Coleman HG, James JA, Salto-Tellez M, Hamilton PW. QuPath: open source software for digital pathology image analysis. Sci Rep. 2017;7(1):16878.
De Luca DA, Papara C, Vorobyev A, Staiger H, Bieber K, Thaçi D, Ludwig RJ. Lichen sclerosus: the 2023 update. Front Med (Lausanne). 2023;10:1106318.
Pilatz A, Altinkilic B, Schormann E, Maegel L, Izykowski N, Becker J, Weidner W, Kreipe H, Jonigk D. Congenital phimosis in patients with and without lichen sclerosus: distinct expression patterns of tissue remodeling associated genes. J Urol. 2013;189(1):268–74.
Edmonds EV, Oyama N, Chan I, Francis N, McGrath JA, Bunker CB. Extracellular matrix protein 1 autoantibodies in male genital lichen sclerosus. Br J Dermatol. 2011;165(1):218–9.
Kaya G, Augsburger E, Stamenkovic I, Saurat JH. Decrease in epidermal CD44 expression as a potential mechanism for abnormal hyaluronate accumulation in superficial dermis in lichen sclerosus et atrophicus. J Invest Dermatol. 2000;115(6):1054–8.
Kaya G, Saurat JH. Restored epidermal CD44 expression in lichen sclerosus et atrophicus and clinical improvement with topical application of retinaldehyde. Br J Dermatol. 2005;152(3):570–2.
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