Traditional Chinese Medicine for Pediatric Allergic Diseases

Wang J, Zhou Y, Zhang H, et al. Pathogenesis of allergic diseases and implications for therapeutic interventions. Sig Transduct Target Ther. 2023;8:138. https://doi.org/10.1038/s41392-023-01344-4

Article  CAS  Google Scholar 

Lee ECK, Trogen B, Brady K, Ford L, Wang S. The natural history and risk factors for the development of food allergies in children and adults. Curr Allergy Asthma Rep. 2024;24:121–31. https://doi.org/10.1007/s11882-024-01131-3

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang L, Fu J, Zhou Y. Research Progress in Atopic March. Front Immunol. 2020;11(1907)https://doi.org/10.3389/fimmu.2020.01907

Anvari S, Miller J, Yeh C, Davis CM. IgE-Mediated food allergy. Clin Rev Allergy Immunol. 2019;57(2):244–60. https://doi.org/10.1007/s12016-018-8710-3

Article  CAS  PubMed  Google Scholar 

Peters RL, Krawiec M, Koplin JJ, Santos AF. Update on food allergy. Pediatr Allergy Immunol. 2021;32(4):647–57. https://doi.org/10.1111/pai.13443

Article  PubMed  PubMed Central  Google Scholar 

Patel N, Herbert L, Green TD. The emotional, social, and financial burden of food allergies on children and their families. Allergy Asthma Proc. 2017;38(2):88–91. https://doi.org/10.2500/aap.2017.38.4028

Langan SM, Mulick AR, Rutter CE, et al. Trends in eczema prevalence in children and adolescents: A global asthma network phase I study. Clin Exp Allergy. 2022;2023(53):337–52. https://doi.org/10.1111/cea.14276

Article  Google Scholar 

Nemeth V, Syed HA, Evans J. Eczema. StatPearls. StatPearls Publishing Copyright © 2025, StatPearls Publishing LLC. 2025.

NCHS. Data from: Diagnosed Allergic Conditions in Children Aged 0–17 Years: United States, 2021. 2021. NCHS.

Sitek A, Chiarella SE, Pongdee T. Hypersensitivity reactions to biologics used in the treatment of allergic diseases: clinical features, diagnosis and management. Front Allergy. 2023;4:1219735. https://doi.org/10.3389/falgy.2023.1219735

Article  PubMed  PubMed Central  Google Scholar 

Sitek AN, Li JT, Pongdee T. Risks and safety of biologics: A practical guide for allergists. World Allergy Organ J Jan. 2023;16(1):100737. https://doi.org/10.1016/j.waojou.2022.100737

Article  Google Scholar 

Chen Y, Lin Y, Hu S, Chen H. Characteristics of traditional Chinese medicine users and prescription analysis for pediatric atopic dermatitis: a population-based study. BMC Complement Altern Med. 2016;16(173). https://doi.org/10.1186/s12906-016-1158-1

Cai X, Sun X, Liu L, et al. Efficacy and safety of Chinese herbal medicine for atopic dermatitis: evidence from eight high-quality randomized placebo-controlled trials. Front Pharmacol. 2022;13(927304). https://doi.org/10.3389/fphar.2022.927304

Jia J, Gu SX, Mo X, Liu J, Chen D. An updated systematic review and meta-analysis of efficacy and safety of Chinese herbal medicine for treating atopic dermatitis. J Derm Treat. 2023;34(1). https://doi.org/10.1080/09546634.2023.2268766

Guo Z, Li Y, Hou Y, et al. Chinese herbal bath therapy for the treatment of atopic dermatitis in children: A meta-analysis and systematic review. Medicine. 2022;101(47):e31923. https://doi.org/10.1097/MD.0000000000031923

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wen-Hui H, Chong-min W. Curative effect of TCM medicated bath combined with tacrolimus on moderate to severe atopic dermatitis in children and influence on serum LTB4 on LTC4. Chin J Gen Pract. 2016;14(4):604–606685. https://doi.org/10.16766/j.cnki.issn.1674-4152.2016.04.030

Article  Google Scholar 

Thanik E, Wisniewski JA, Nowak-Wegrzyn A, Sampson H, Li X-M. Effect of traditional Chinese medicine on skin lesions and quality of life in patients with moderate to severe eczema. Ann Allergy. 2018;121(1):135–6. https://doi.org/10.1016/j.anai.2018.03.004

Article  Google Scholar 

Uzun S, Wang Z, McKnight TA, et al. Improvement of skin lesions in corticosteroid withdrawal-associated severe eczema by multicomponent traditional Chinese medicine therapy. Allergy Asthma Clin Immunol. 2021;17(1). https://doi.org/10.1186/s13223-021-00555-0

Liu J, Mo X, Wu D, et al. Efficacy of a Chinese herbal medicine for the treatment of atopic dermatitis: A randomised controlled study. Compl Ther Med. 2015;23(5):664–51. https://doi.org/10.1016/j.ctim.2015.07.006

Article  Google Scholar 

Chen H, Lin Y, Wu J, et al. Use of traditional Chinese medicine reduces exposure to corticosteroid among atopic dermatitis children: A 1-year follow-up cohort study. J Ethnopharm. 2015;159(15):189–96. https://doi.org/10.1016/j.jep.2014.11.018

Article  Google Scholar 

Srivastava K, Yang N, Uzun S, et al. Effect of traditional Chinese medicine (TCM) in moderate-to-severe eczema in clinic and animal model: beyond corticosteroids. J Allergy Clin Immunol. 2020;145(2):AB198. https://doi.org/10.1016/j.jaci.2019.12.291

Article  Google Scholar 

Chang J, Cattelan L, BEn-Shoshan M, Le M, Netchiporouk E. Management of pediatric chronic spontaneous urticaria: A review of current evidence and guidelines. J Asthma Allergy. 2021;14:187–99. https://doi.org/10.2147/JAA.S249765

Article  PubMed  PubMed Central  Google Scholar 

Maurer M, Rosén K, Hsieh HJ, et al. Omalizumab for the treatment of chronic idiopathic or spontaneous urticaria. N Engl J Med. Mar 2013;368(10):924–35. https://doi.org/10.1056/NEJMoa1215372

FDA. FDA Approves First Medication to Help Reduce Allergic Reactions to Multiple Foods After Accidental Exposure. Accessed 04/25/2025, https://www.fda.gov/news-events/press-announcements/fda-approves-first-medication-help-reduce-allergic-reactions-multiple-foods-after-accidental

Edwards T, Palmer V. Theoretical complementary and alternative therapies for papular urticaria: A review of potential treatments based on shared pathophysiology. J Integ Derm. 2024; 2024.

Sachdeva S, Gupta V, Amin SS, Tahseen M. Chronic urticaria. Indian J Dermatol. 2011;56(6):622–8. https://doi.org/10.4103/0019-5154.91817

Article  PubMed  PubMed Central  Google Scholar 

Iraji F, Saghayi M, Mokharti H, Siadat A. The efficacy of acupuncture in the patients with chronic urticaria: acupuncture in the treatment of chronic urticaria: A double blind study. Int J Dermatol. 2006;3(2).

Hizil P, Gulcen B, Kilic F. Acupuncture enhances quality of life and disease control in chronic spontaneous urticaria patients on omalizumab: A study of 61 cases. Med Sci Monit. 2024;30:e945935. https://doi.org/10.12659/MSM.945935

Article  Google Scholar 

Zheng Q, Zheng H, Zhou S, et al. Efficacy of acupuncture treatment for chronic spontaneous urticaria: study protocol for a randomised controlled trial. BMJ Open. 2022;12(2):e045027. https://doi.org/10.1136/bmjopen-2020-045027

Article  PubMed  PubMed Central  Google Scholar 

Fan X, McKnight A, Neshiwat J, Park S, Chung D, Li X-M. Successful management of chronic urticaria and food allergies in a pediatric population using integrative traditional Chinese medicine therapy: a case series. Clin Mol Allergy. 2022;20(1):12. https://doi.org/10.1186/s12948-022-00175-y

Article  PubMed  PubMed Central  Google Scholar 

Votto M, De Filippo M, Caimmi S, et al. A practical update on pediatric eosinophilic esophagitis. Child (Basel). 2023;10(10):1620. https://doi.org/10.3390/children10101620

Article  Google Scholar 

Liu X, Xiao X, Liu D, Tan C. A meta-analysis on randomized controlled trials of treating eosinophilic esophagitis with Budesonide. Gastro Hepato. 2022;54(1):2078–88. https://doi.org/10.1080/07853890.2022.2101689

Article  CAS  Google Scholar 

Hannan N, Steel A, Tiralongo E, McMillan SS. What influences complementary medicine use for children with eosinophilic esophagitis? Findings from a cross-sectional survey. Compl Ther Clin Pract. 2021;45:101448. https://doi.org/10.1016/j.ctcp.2021.101448

Article  Google Scholar 

Steel A, McIntyre E, Harnett J, et al. Complementary medicine use in the Australian population: results of a nationally-representative cross-sectional survey. Sci Rep. 2018;8(17325). https://doi.org/10.1038/s41598-018-35508-y

Gao L, Bai X. Clinical trial of acupuncture treatment of Gastro-esophageal reflex disease by needling dorsal segment of the governor vessel. Zhen Ci Yan Jiu. 2016;41(2):150–3.

PubMed  Google Scholar 

Efendieva MT. Efficacy of acupuncture in the treatment of patients with gastroesophageal reflux disease. Eksp Klin Gastroenterol. 2013;5:49–52.

Google Scholar 

Setright. Prevention of symptoms of gastric irritation (GERD) using two herbal formulas: an observational study. J Australian Trad-Med Soc. 2017;23(2):68–71. https://doi.org/10.3316/informit.950298610899394

Article  Google Scholar 

Smith N, Acupuncture, Eosinophilic Esophagitis. &. AllergicChild blog. 2020. Accessed 01 Feb 2025. https://home.allergicchild.com/acupuncture-eosinophilic-esophagitis/

Soffer G, Kaman K, Li X-M. Successful management of eosinophilic esophagitis using traditional Chinese medicine: A case report. Yale J Biol Med. 2020;93(5):685–8.

PubMed  PubMed Central  Google Scholar 

Maskey AR, Wang ZZ, Chen X, et al. A flavonoid compound 7, 4 dihydroxy flavone as a potential therapeutic for the treatment and management of EoE. FASEB. 2022;36(S1). https://doi.org/10.1096/fasebj.2022.36.S1.R4598

Maskey AR, Wang ZZ, Chen X et al. Computational analysis to define efficacy & molecular mechanisms of 7, 4’- Dihydroxyflavone on eosinophilic esophagitis: Ex-vivo validation in human esophagus biopsies. Front Immunol. 2022;13(2022)https://doi.org/10.3389/fimmu.2022.1015437

Gupta RS, Warren CM, Smith BM, et al. The public health impact of Parent-Reported childhood food allergies in the united States. Pediatrics Dec. 2018;142(6). https://doi.org/10.1542/peds.2018-1235

Warren CM, Sehgal S, Sicherer SH, Gupta RS. Epidemiology and the growing epidemic of food allergy in children and adults across the Globe. Curr Allergy Asthma Rep Mar. 2024;24(3):95–106. https://doi.org/10.1007/s11882-023-01120-y

Article  CAS  Google Scholar 

Sindher SB, Hillier C, Anderson B, Long A, Chinthrajah RS. Treatment of food allergy: oral immunotherapy, biologics, and beyond. Ann Allergy Asthma Immunol Jul. 2023;131(1):29–36. https://doi.org/10.1016/j.anai.2023.04.023

Article  CAS  Google Scholar 

Ezhuthachan ID, Beaudoin M, Nowak-Wegrzyn A, Vickery BP. The future of food allergy management: advancements in therapies. Curr Allergy Asthma Rep Apr. 2024;24(4):161–71. https://doi.org/10.1007/s11882-024-01133-1

Article  Google Scholar 

Khodoun MV, Morris SC, Shao WH, et al. Suppression of IgE-mediated anaphylaxis and food allergy with monovalent anti-FcεRIα mAbs. J Allergy Clin Immunol May. 2021;147(5):1838–e18544. https://doi.org/10.1016/j.jaci.2020.10.045

Comments (0)

No login
gif