Papanicolas I, Woskie LR, Jha AK. Health care spending in the United States and other high-income countries. JAMA. 2018;319(10):1024–39. https://doi.org/10.1001/JAMA.2018.1150.
Kazi DS, Elkind MSV, Deutsch A, et al. Forecasting the economic burden of cardiovascular disease and stroke in the United States through 2050: a presidential advisory from the American Heart Association. Circulation. 2024;150(4):e89–101. https://doi.org/10.1161/CIR.0000000000001258.
Emanuel EJ, Gudbranson E, Van Parys J, Grtz M, Helgeland J, Skinner J. Comparing Health Outcomes of Privileged US Citizens With Those of Average Residents of Other Developed Countries. JAMA Intern Med. 2021;181(3):339–44. https://doi.org/10.1001/JAMAINTERNMED.2020.7484.
Article PubMed PubMed Central Google Scholar
Mokdad AH, Bisignano C, Hsu JM, et al. The burden of diseases, injuries, and risk factors by state in the USA, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;404(10469):2314–40. https://doi.org/10.1016/S0140-6736(24)01446-6.
Murray CJL, Mokdad AH, Ballestros K, et al. The state of US health, 1990–2016: burden of diseases, injuries, and risk factors among US states. JAMA. 2018;319(14):1444–72. https://doi.org/10.1001/JAMA.2018.0158.
Article PubMed PubMed Central Google Scholar
He J, Zhu Z, Bundy JD, Dorans KS, Chen J, Hamm LL. Trends in cardiovascular risk factors in US adults by race and ethnicity and socioeconomic status, 1999–2018. JAMA. 2021;326(13):1286–98. https://doi.org/10.1001/JAMA.2021.15187.
Article PubMed PubMed Central Google Scholar
Berwick DM, Batchlor E, Chokshi DA, et al. From laggard to leader: why health care in the United States is failing, and how to fix it. Health Aff (Millwood). 2025;44(2):179–86. https://doi.org/10.1377/HLTHAFF.2024.01007.
Outland BE, Erickson S, Doherty R, Fox W, Ward L. Reforming physician payments to achieve greater equity and value in health care: a position paper of the American College of Physicians. Ann Intern Med. 2022;175(7):1019–21. https://doi.org/10.7326/M21-4484.
Dzau VJ, McClellan MB, McGinnis JM, et al. Vital directions for health and health care: priorities from a National Academy of Medicine initiative. JAMA. 2017;317(14):1461–70. https://doi.org/10.1001/JAMA.2017.1964.
Saini V, Garcia-Armesto S, Klemperer D, et al. Drivers of poor medical care. Lancet. 2017;390(10090):178–90. https://doi.org/10.1016/S0140-6736(16)30947-3.
Chobanian AV. The hypertension paradox - More uncontrolled disease despite improved therapy. New Arm Med J. 2009;3(4):60–70. https://doi.org/10.1056/NEJMSA0903829.
Lu Y, Brush JE, Kim C, et al. Delayed hypertension diagnosis and its association with cardiovascular treatment and outcomes. JAMA Netw Open. 2025;8(7):e2520498–e2520498. https://doi.org/10.1001/JAMANETWORKOPEN.2025.20498.
Article PubMed PubMed Central Google Scholar
Khan SS, Berwanger O, Fiuzat M, et al. Prioritising the primary prevention of heart failure. Lancet. 2025;406(10508):1138–53. https://doi.org/10.1016/S0140-6736(25)01393-5.
Rosenberg BL, Kellar JA, Labno A, et al. Quantifying geographic variation in health care outcomes in the United States before and after risk-adjustment. PLoS One. 2016. https://doi.org/10.1371/JOURNAL.PONE.0166762.
Article PubMed PubMed Central Google Scholar
Tsugawa Y, Jha AK, Newhouse JP, Zaslavsky AM, Jena AB. Variation in physician spending and association with patient outcomes. JAMA Intern Med. 2017;177(5):675–82. https://doi.org/10.1001/JAMAINTERNMED.2017.0059.
Article PubMed PubMed Central Google Scholar
Hines S, Joshi MS. Variation in quality of care within health systems. Jt Comm J Qual Patient Saf. 2008;34(6):326–32. https://doi.org/10.1016/S1553-7250(08)34041-0.
Desroches CM, Wachenheim D, Garcia A, et al. Clinician and patient perspectives on the exchange of sensitive social determinants of health information. JAMA Netw Open. 2024;7(10):e2444376–e2444376. https://doi.org/10.1001/JAMANETWORKOPEN.2024.44376.
Article PubMed PubMed Central Google Scholar
Kini V, Breathett K, Groeneveld PW, et al. Strategies to reduce low-value cardiovascular care: a scientific statement from the American Heart Association. Circ Cardiovasc Qual Outcomes. 2022;15(3):e000105. https://doi.org/10.1161/HCQ.0000000000000105.
Article PubMed PubMed Central Google Scholar
Small AM, Watson NW, Wadhera RK, Secemsky EA, Yeh RW. Advancing Health Equity in the Cardiovascular Device Life Cycle. Circ Cardiovasc Qual Outcomes. 2025;18(3). https://doi.org/10.1161/CIRCOUTCOMES.124.011310.
Lu Y, Liu Y, Dhingra LS, et al. National trends in racial and ethnic disparities in use of recommended therapies in adults with atherosclerotic cardiovascular disease, 1999–2020. JAMA Netw Open. 2023;6(12):e2345964–e2345964. https://doi.org/10.1001/JAMANETWORKOPEN.2023.45964.
Article PubMed PubMed Central Google Scholar
Shen YC, Sarkar N, Hsia RY. Differential treatment and outcomes for patients with heart attacks in advantaged and disadvantaged communities. J Am Heart Assoc. 2023. https://doi.org/10.1161/JAHA.122.030506.
Article PubMed PubMed Central Google Scholar
Pierce JB, Ng SM, Stouffer JA, Williamson CA, Stouffer GA. Rural/urban disparities in cardiovascular disease in the US-what can be done to improve outcomes for rural Americans? Am J Cardiol. 2025;248:10–5. https://doi.org/10.1016/J.AMJCARD.2025.03.033.
Breathett K, Lewsey S, Brownell NK, et al. Implementation science to achieve equity in heart failure care: a scientific statement from the American Heart Association. Circulation. 2024;149(19):E1143–63. https://doi.org/10.1161/CIR.0000000000001231.
Article PubMed PubMed Central Google Scholar
Tasmurzayev N, Amangeldy B, Imanbek B, et al. Digital cardiovascular twins, AI agents, and sensor data: a narrative review from system architecture to proactive heart health. Sensors. 2025;25(17):5272. https://doi.org/10.3390/s25175272.
Article PubMed PubMed Central Google Scholar
Shajari S, Kuruvinashetti K, Komeili A, Sundararaj U. The emergence of AI-based wearable sensors for digital health technology: a review. Sensors. 2023. https://doi.org/10.3390/s23239498.
Article PubMed PubMed Central Google Scholar
Huang JD, Wang J, Ramsey E, Leavey G, Chico TJA, Condell J. Applying artificial intelligence to wearable sensor data to diagnose and predict cardiovascular disease: a review. Sensors. 2022. https://doi.org/10.3390/s22208002.
Article PubMed PubMed Central Google Scholar
Armoundas AA, Narayan SM, Arnett DK, et al. Use of artificial intelligence in improving outcomes in heart disease: a scientific statement from the American Heart Association. Circulation. 2024;149(14):E1028–50. https://doi.org/10.1161/CIR.0000000000001201.
Article PubMed PubMed Central Google Scholar
Marvasti TB, Gao Y, Murray KR, Hershman S, McIntosh C, Moayedi Y. Unlocking tomorrow’s health care: expanding the clinical scope of wearables by applying artificial intelligence. Canadian J Cardiology Elsevier Inc. 2024;40(10):1934–45. https://doi.org/10.1016/j.cjca.2024.07.009.
Chandrasekaran R, Muhammed Sadiq T, Moustakas E. Usage trends and data sharing practices of healthcare wearable devices among US adults: cross-sectional study. J Med Internet Res. 2025. https://doi.org/10.2196/63879.
Article PubMed PubMed Central Google Scholar
Spatz ES, Ginsburg GS, Rumsfeld JS, Turakhia MP. Wearable digital health technologies for monitoring in cardiovascular medicine. N Engl J Med. 2024;390(4):346–56. https://doi.org/10.1056/nejmra2301903.
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