Echocardiography in HIV Disease

World Health Organization. HIV data and statistics. (https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/hiv/strategic-information/hiv-data-and-statistics)

Shah ASV, Stelzle D, Lee KK, et al. Global burden of atherosclerotic cardiovascular disease in people living with HIV: systematic review and meta-analysis. Circulation. 2018;138(11):1100–12. https://doi.org/10.1161/CIRCULATIONAHA.117.033369.

Article  PubMed Central  PubMed  Google Scholar 

Feinstein MJ, Hsue PY, Benjamin LA, et al. Characteristics, prevention, and management of cardiovascular disease in people living with HIV: a scientific statement from the American Heart Association. Circulation. 2019;140(2):e98–124. https://doi.org/10.1161/CIR.0000000000000695.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Freiberg MS, Duncan MS, Alcorn C, et al. HIV infection and the risk of World Health Organization-defined sudden cardiac death. J Am Heart Assoc. 2021;10(18):e021268. https://doi.org/10.1161/JAHA.121.021268.

Article  PubMed Central  PubMed  Google Scholar 

Durstenfeld MS, Thakkar A, Jeon D, et al. HIV-associated heart failure: phenotypes and clinical outcomes in a safety-net setting. J Am Heart Assoc. 2024;13(23):e036467. https://doi.org/10.1161/JAHA.124.036467.

Article  PubMed Central  PubMed  Google Scholar 

Heidenreich PA, Eisenberg MJ, Kee LL, et al. Pericardial effusion in AIDS. Incidence and survival. Circulation. 1995;92(11):3229–34. https://doi.org/10.1161/01.cir.92.11.3229.

Article  CAS  PubMed  Google Scholar 

Remick J, Georgiopoulou V, Marti C, et al. Heart failure in patients with human immunodeficiency virus infection: epidemiology, pathophysiology, treatment, and future research. Circulation. 2014;129(17):1781–9. https://doi.org/10.1161/CIRCULATIONAHA.113.004574.

Article  PubMed Central  PubMed  Google Scholar 

Bloomfield GS, Alenezi F, Barasa FA, Lumsden R, Mayosi BM, Velazquez EJ. Human immunodeficiency virus and heart failure in low- and middle-income countries. JACC Heart Fail. 2015;3(8):579–90. https://doi.org/10.1016/j.jchf.2015.05.003.

Article  PubMed Central  PubMed  Google Scholar 

Ntsekhe M, Baker JV. Cardiovascular disease among persons living with HIV: new insights into pathogenesis and clinical manifestations in a global context. Circulation. 2023;147(1):83–100. https://doi.org/10.1161/CIRCULATIONAHA.122.057443.

Article  PubMed  Google Scholar 

Dharmarajan K, Rich MW. Epidemiology, pathophysiology, and prognosis of heart failure in older adults. Heart Fail Clin. 2017;13(3):417–26. https://doi.org/10.1016/j.hfc.2017.02.001.

Article  PubMed  Google Scholar 

Mitchell C, Rahko PS, Blauwet LA, et al. Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr. 2019;32(1):1–64. https://doi.org/10.1016/j.echo.2018.06.004.

Article  PubMed  Google Scholar 

Kaplan RC, Hanna DB, Kizer JR. Recent insights into cardiovascular disease (CVD) risk among HIV-infected adults. Curr HIV AIDS Rep. 2016;13(1):44–52. https://doi.org/10.1007/s11904-016-0301-4.

Article  PubMed Central  PubMed  Google Scholar 

Lang RM, Badano LP, Mor-Avi V, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28(1):1-39 e14. https://doi.org/10.1016/j.echo.2014.10.003.

Article  PubMed  Google Scholar 

Smiseth OA, Rider O, Cvijic M, Valkovic L, Remme EW, Voigt JU. Myocardial strain imaging: theory, current practice, and the future. JACC Cardiovasc Imaging. 2025;18(3):340–81. https://doi.org/10.1016/j.jcmg.2024.07.011.

Article  PubMed  Google Scholar 

Mihos CG, Liu JE, Anderson KM, et al. Speckle-tracking strain echocardiography for the assessment of left ventricular structure and function: a scientific statement from the American Heart Association. Circulation. 2025;152(10):e96–109. https://doi.org/10.1161/CIR.0000000000001354.

Article  PubMed  Google Scholar 

Cerrato E, D’Ascenzo F, Biondi-Zoccai G, et al. Cardiac dysfunction in pauci symptomatic human immunodeficiency virus patients: a meta-analysis in the highly active antiretroviral therapy era. Eur Heart J. 2013;34(19):1432–6. https://doi.org/10.1093/eurheartj/ehs471.

Article  CAS  PubMed  Google Scholar 

Erqou S, Lodebo BT, Masri A, et al. Cardiac dysfunction among people living with HIV: a systematic review and meta-analysis. JACC: Heart Failure. 2019;7(2):98–108. https://doi.org/10.1016/j.jchf.2018.10.006.

Article  PubMed  Google Scholar 

D’Souza G, Bhondoekhan F, Benning L, et al. Characteristics of the MACS/WIHS combined cohort study: opportunities for research on aging with HIV in the longest US observational study of HIV. Am J Epidemiol. 2021;190(8):1457–75. https://doi.org/10.1093/aje/kwab050.

Article  PubMed Central  PubMed  Google Scholar 

de Doria Vasconcellos H, Post WS, Ervin AM, et al. Associations between HIV serostatus and cardiac structure and function evaluated by 2-dimensional echocardiography in the Multicenter AIDS Cohort Study. J Am Heart Assoc. 2021;10(7):e019709. https://doi.org/10.1161/JAHA.120.019709.

Article  Google Scholar 

Shitole SG, Lazar JM, Taub CC, et al. Human immunodeficiency virus and cardiac end-organ damage in women: findings from an echocardiographic study across the United States. Clin Infect Dis. 2023;76(2):210–9. https://doi.org/10.1093/cid/ciac795.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Shitole SG, Lazar JM, Hanna DB, et al. HIV, hepatitis C virus and risk of new-onset left ventricular dysfunction in women. AIDS. 2021;35(10):1647–55. https://doi.org/10.1097/QAD.0000000000002920.

Article  PubMed Central  PubMed  Google Scholar 

Wu KC, Haberlen SA, Plankey MW, et al. Human immunodeficiency viral infection and differences in interstitial ventricular fibrosis and left atrial size. Eur Heart J Cardiovasc Imaging. 2021;22(8):888–95. https://doi.org/10.1093/ehjci/jeab037.

Article  PubMed Central  PubMed  Google Scholar 

Kato Y, Ambale-Venkatesh B, Naveed M, et al. HIV, HIV-specific factors, and myocardial disease in women. Clin Infect Dis. 2024;79(2):451–61. https://doi.org/10.1093/cid/ciae077.

Article  PubMed Central  PubMed  Google Scholar 

Gandhi RT, Landovitz RJ, Sax PE, et al. Antiretroviral drugs for treatment and prevention of HIV in adults: 2024 recommendations of the International Antiviral Society-USA Panel. JAMA. 2025;333(7):609–28. https://doi.org/10.1001/jama.2024.24543.

Article  CAS  PubMed  Google Scholar 

Freiberg MS, Chang CH, Skanderson M, et al. Association between HIV infection and the risk of heart failure with reduced ejection fraction and preserved ejection fraction in the antiretroviral therapy era: results from the Veterans Aging Cohort Study. JAMA Cardiol. 2017;2(5):536–46. https://doi.org/10.1001/jamacardio.2017.0264.

Article  PubMed Central  PubMed  Google Scholar 

Beydoun N, Nance RM, Durstenfeld MS, et al. Multicenter study of heart failure phenotypes and physician-adjudicated causes in people with HIV. AIDS. 2025;39(9):1246–53. https://doi.org/10.1097/QAD.0000000000004182.

Article  PubMed Central  PubMed  Google Scholar 

Nagueh SF, Sanborn DY, Oh JK, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography and for heart failure with preserved ejection fraction diagnosis: an update from the American Society of Echocardiography. J Am Soc Echocardiogr. 2025;38(7):537–69. https://doi.org/10.1016/j.echo.2025.03.011.

Article  PubMed  Google Scholar 

Nagueh SF, Smiseth OA, Appleton CP, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2016;29(4):277–314. https://doi.org/10.1016/j.echo.2016.01.011.

Article  PubMed  Google Scholar 

Butler J, Greene SJ, Shah SH, et al. Diastolic dysfunction in patients with human immunodeficiency virus receiving antiretroviral therapy: results from the CHART Study. J Card Fail. 2020;26(5):371–80. https://doi.org/10.1016/j.cardfail.2019.10.011.

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