Sahraei Z, Saffaei A, Alavi Darazam I, Salamzadeh J, Shabani M, Shokouhi S, et al. Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearances: a randomized clinical trial. Front Pharmacol. 2022;13:1041152. https://doi.org/10.3389/fphar.2022.1041152.
Article CAS PubMed PubMed Central Google Scholar
Food and drug administration. Vancomycin hydrochloride for injection USP [Internet]. http://www.accessdata.fda.gov/drugsatfda_docs/label/2017/060180s048lbl.pdf.
European society of clinical microbiology and infectious diseases. Rationale for the EUCAST clinical breakpoints, version 2.1 [Internet]. https://www.eucast.org/publications-and-documents/rd.
Rybak MJ, Le J, Lodise TP, Levine DP, Bradley JS, Liu C, et al. Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: a revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. Clin Infect Dis. 2020;71:1361–4. https://doi.org/10.1093/cid/ciaa303.
Article CAS PubMed Google Scholar
Moise-Broder PA, Forrest A, Birmingham MC, Schentag JJ. Pharmacodynamics of vancomycin and other antimicrobials in patients with Staphylococcus aureus lower respiratory tract infections. Clin Pharmacokinet. 2004;43:925–42. https://doi.org/10.2165/00003088-200443130-00005.
Article CAS PubMed Google Scholar
Abdul-Aziz MH, Alffenaar J-WC, Bassetti M, Bracht H, Dimopoulos G, Marriott D, et al. Antimicrobial therapeutic drug monitoring in critically ill adult patients: a position paper. Intensive Care Med. 2020;46:1127–53. https://doi.org/10.1007/s00134-020-06050-1.
Article PubMed PubMed Central Google Scholar
Lodise JTP, Rosenkranz SL, Finnemeyer M, Evans S, Sims M, Zervos MJ, et al. The Emperor’s New Clothes: prospective observational evaluation of the association between initial vancomycIn exposure and failure rates among adult hospitalized patients with methicillin-resistant Staphylococcus aureus bloodstream infections. Clin Infect Dis. 2020;70:1536–45. https://doi.org/10.1093/cid/ciz460
Aljefri DM, Avedissian SN, Rhodes NJ, Postelnick MJ, Nguyen K, Scheetz MH. Vancomycin area under the curve and acute kidney injury: a meta-analysis. Clin Infect Dis. 2019;69:1881–7. https://doi.org/10.1093/cid/ciz051.
Article CAS PubMed PubMed Central Google Scholar
Abdelmessih E, Patel N, Vekaria J, Crovetto B, SanFilippo S, Adams C, et al. Vancomycin area under the curve versus trough only guided dosing and the risk of acute kidney injury: systematic review and meta-analysis. Pharmacotherapy. 2022;42:741–53. https://doi.org/10.1002/phar.2722.
Article CAS PubMed Google Scholar
Thijs L, Quintens C, Vander Elst L, De Munter P, Depypere M, Metsemakers W-J, et al. Clinical efficacy and safety of vancomycin continuous infusion in patients treated at home in an outpatient parenteral antimicrobial therapy program. Antibiotics. 2022;11:702. https://doi.org/10.3390/antibiotics11050702.
Article CAS PubMed PubMed Central Google Scholar
Telles JP, Morales R, Yamada CH, Marins TA, D’Amaro Juodinis V, Sztajnbok J, et al. Optimization of antimicrobial stewardship programs using therapeutic drug monitoring and pharmacokinetics–pharmacodynamics protocols: a cost-benefit review. Ther Drug Monit. 2023;45:200–8. https://doi.org/10.1097/FTD.0000000000001067.
Hall NM, Brown ML, Edwards WS, Oster RA, Cordell W, Stripling J. Model-informed precision dosing improves outcomes in patients receiving vancomycin for gram-positive infections. Open Forum Infect Dis. 2024;11:ofae002. https://doi.org/10.1093/ofid/ofae002.
Article CAS PubMed PubMed Central Google Scholar
Darwich AS, Ogungbenro K, Vinks AA, Powell JR, Reny J-L, Marsousi N, et al. Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future. Clin Pharmacol Ther. 2017;101:646–56. https://doi.org/10.1002/cpt.659.
Article CAS PubMed Google Scholar
Swartling M, Hamberg A-K, Furebring M, Tängdén T, Nielsen EI. Model-informed precision dosing of vancomycin in clinical practice: an intervention development study. Int J Clin Pharm. 2025;47:178–86. https://doi.org/10.1007/s11096-024-01822-x.
Darwich AS, Polasek TM, Aronson JK, Ogungbenro K, Wright DFB, Achour B, et al. Model-informed precision dosing: background, requirements, validation, implementation, and forward trajectory of individualizing drug therapy. Annu Rev Pharmacol Toxicol. 2021;61:225–45. https://doi.org/10.1146/annurev-pharmtox-033020-113257.
Article CAS PubMed Google Scholar
. Kantasiripitak W, Van Daele R, Gijsen M, Ferrante M, Spriet I, Dreesen E. Software tools for model-informed precision dosing: how well do they satisfy the needs? Front Pharmacol. 2020;11:620. https://doi.org/10.3389/fphar.2020.00620.
Article PubMed PubMed Central Google Scholar
Minichmayr IK, Dreesen E, Centanni M, Wang Z, Hoffert Y, Friberg LE, et al. Model-informed precision dosing: state of the art and future perspectives. Adv Drug Deliv Rev. 2024;215:115421. https://doi.org/10.1016/j.addr.2024.115421.
Article CAS PubMed Google Scholar
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. https://doi.org/10.1136/bmj.n71.
Article PubMed PubMed Central Google Scholar
Dia N. Precision dosing of vancomycin: a systematic review of population pharmacokinetics Models and comparative evaluation of software tools [Internet]. Open Sci. Framew. OSF. https://osf.io/48sfb/?view_only=3f3f3deb75af4dd1a3a03bcc4bdfc258.
Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan—a web and mobile app for systematic reviews. Syst Rev. 2016;5:210. https://doi.org/10.1186/s13643-016-0384-4.
Article PubMed PubMed Central Google Scholar
Wickham H, Averick M, Bryan J, Chang W, McGowan L, François R, et al. Welcome to the Tidyverse. J Open Source Softw. 2019;4:1686. https://doi.org/10.21105/joss.01686.
Colin PJ, Allegaert K, Thomson AH, Touw DJ, Dolton M, De Hoog M, et al. Vancomycin pharmacokinetics throughout life: results from a pooled population analysis and evaluation of current dosing recommendations. Clin Pharmacokinet. 2019;58:767–80. https://doi.org/10.1007/s40262-018-0727-5.
Article CAS PubMed Google Scholar
Holford N, O’Hanlon CJ, Allegaert K, Anderson B, Falcão A, Simon N, et al. A physiological approach to renal clearance: from premature neonates to adults. Br J Clin Pharmacol. 2024;90:1066–80. https://doi.org/10.1111/bcp.15978.
De Cock RFW, Allegaert K, Brussee JM, Sherwin CMT, Mulla H, De Hoog M, et al. Simultaneous pharmacokinetic modeling of gentamicin, tobramycin and vancomycin clearance from neonates to adults: towards a semi-physiological function for maturation in glomerular filtration. Pharm Res. 2014;31:2643–54. https://doi.org/10.1007/s11095-014-1361-z.
Article CAS PubMed PubMed Central Google Scholar
Avedissian SN, Bradley E, Zhang D, Bradley JS, Nazer LH, Tran TM, et al. Augmented renal clearance using population-based pharmacokinetic modeling in critically ill pediatric patients. Pediatr Crit Care Med. 2017;18:e388–94. https://doi.org/10.1097/PCC.0000000000001228.
Bang J, Kang HI, Lee H, Chong YP, Hong S, Lee E, et al. Development of a new pharmacokinetic model for target‐concentration controlled infusion of vancomycin in critically ill patients. Clin Exp Pharmacol Physiol. 2022;49:202–11. https://doi.org/10.1111/1440-1681.13597.
Article CAS PubMed Google Scholar
Belavagi D, Bhandari RK, Shafiq N, Gota V, Patil A, Pandey AK, et al. A study to explore the appropriateness of dosing regimen of vancomycin in critically ill patients in a tertiary care unit of India. Germs. 2022;12:238–52. https://doi.org/10.18683/germs.2022.1326.
Article CAS PubMed PubMed Central Google Scholar
Escobar L, Andresen M, Downey P, Gai MN, Regueira T, Bórquez T, et al. Population pharmacokinetics and dose simulation of vancomycin in critically ill patients during high-volume haemofiltration. Int J Antimicrob Agents. 2014;44:163–7. https://doi.org/10.1016/j.ijantimicag.2014.03.009.
Article CAS PubMed Google Scholar
Garreau R, Falquet B, Mioux L, Bourguignon L, Ferry T, Tod M, et al. Population pharmacokinetics and dosing simulation of vancomycin administered by continuous injection in critically ill patient. Antibiotics. 2021;10:1228. https://doi.org/10.3390/antibiotics10101228.
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