Julian Bryan

Present address: Molecular Diagnostics Laboratory, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

These authors contributed equally: Jack Y. Ghannam, Julian Bryan, Jakob Weiss, Daniel Kovarsky, David Merrell.

These authors jointly supervised this work: Itay Tirosh, David A. Reardon, Gad Getz, Catherine J. Wu.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

Jack Y. Ghannam, Julian Bryan, J. Thomas Janes III, McKayla Van Orden, Emma S. Lin, Shuqiang Li & Catherine J. Wu

Harvard Medical School, Boston, MA, USA

Jack Y. Ghannam, Julian Bryan, Gilbert Youssef, Gad Getz & Catherine J. Wu

Broad Institute of MIT and Harvard, Cambridge, MA, USA

Jack Y. Ghannam, Julian Bryan, Jakob Weiss, David Merrell, Conor Messer, Kristy Schlueter-Kuck, Brian P. Danysh, Shuqiang Li, Keith L. Ligon, Gad Getz & Catherine J. Wu

Harvard/MIT MD-PhD Program and Harvard Immunology PhD Program, Harvard Medical School, Boston, MA, USA

Jack Y. Ghannam

Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

Julian Bryan & Keith L. Ligon

Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

Daniel Kovarsky & Itay Tirosh

Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA

Geoffrey G. Fell & Donna Neuberg

Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

Mary Jane Lim-Fat

Center for Neuro-Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

Gilbert Youssef, Patrick Y. Wen & David A. Reardon

Department of Radiation Oncology, Brigham and Women’s Hospital, Boston, MA, USA

Rifaquat Rahman

Department of Imaging, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA, USA

Lei Qin

Departments of Radiology, Mass General Brigham, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA, USA

Geoffrey S. Young & Raymond Y. Huang

Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA

J. Thomas Janes III, McKayla Van Orden & Shuqiang Li

Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

Kathleen L. Pfaff & Andrew Gans

IBM Research, Yorktown Heights, NY, USA

Laxmi Parida

Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute & Department of Neurosurgery, Mass General Brigham, Boston, MA, USA

E. Antonio Chiocca

Department of Pathology, Dana-Farber Cancer Institute, Boston, MA, USA

Keith L. Ligon

Cancer Center and Department of Pathology, Massachusetts General Hospital, Boston, MA, USA

Gad Getz