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Activation of Cascade‐Like Antitumor Immune Responses through In Situ Doxorubicin Stimulation and Blockade of Checkpoint Coinhibitory Receptor TIGIT
Abstract Although T cell centered immune checkpoint blockade (ICB) therapies have shown unprecedented success in various c...
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Biomimetic Scaffolds Modulate the Posttraumatic Inflammatory Response in Articular Cartilage Contributing to Enhanced Neoformation of Cartilaginous Tissue In Vivo (Adv. Healthcare Mater. 1/2022)
Cartilage Repair In article number 2101127 by Lewis W. Francis, Francesca Taraballi, and co-workers, a biomimetic immune t...
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Masthead: (Adv. Healthcare Mater. 1/2022)
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Happy 10th Birthday Advanced Healthcare Materials!
It is again that time of the year, when I step back from my daily tasks and reflect on what happened with the journal in t...
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Flexibly Deformable Collagen Hydrogel Tube Reproducing Immunological Tissue Deformation of Blood Vessels as a Pharmacokinetic Testing Model (Adv. Healthcare Mater. 1/2022)
Collagen Hydrogels In article number 2101509 by Shun Itai and Hiroaki Onoe, an immunological deformation reaction of blood...
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Activation of Cascade‐Like Antitumor Immune Responses through In Situ Doxorubicin Stimulation and Blockade of Checkpoint Coinhibitory Receptor TIGIT (Adv. Healthcare Mater. 1/2022)
Enzyme-Responsive Drug Release In article number 2102080, Zhengbao Zha, Hua Wang, and co-workers encapsulate chemotherapeu...
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Engineered Mesenchymal Stem Cells as a Biotherapy Platform for Targeted Photodynamic Immunotherapy of Breast Cancer
Abstract Interleukin-12 (IL12) is a pleiotropic cytokine with promising prospects for cancer immunotherapy. Though IL12 ge...
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Design of Light‐activated Nanoplatform Through Boosting “eat me” Signals for Improved CD47‐blocking Immunotherapy
Abstract Here, we propose a light-activated reactive oxygen species (ROS)-responsive nanoplatform that can boost immunogen...
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Flexible optogenetic transducer device for remote neuron modulation using highly upconversion efficient dendrite‐like gold inverse opaline structure
Abstract Optogenetic engineering has become an increasingly versatile approach in neuroscience because of its great specif...
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Mimicking Native Heart Tissue Physiology and Pathology in Silk Fibroin Constructs Through Perfusion‐based Dynamic Mechanical Stimulation Microdevice
Abstract In vitro cardiomyocyte maturation is an imperative step to replicate native heart tissue-like structures as cardi...
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Template‐Enabled Biofabrication of Thick Three‐Dimensional Tissues with Patterned Perfusable Macro‐Channels
Abstract Interconnected pathways in three-dimensional (3D) bioartificial organs are essential to retaining cell activity i...
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Mapping Macrophage Polarization and Origin during the Progression of the Foreign Body Response to a Poly(ethylene glycol) Hydrogel Implant
Abstract Poly(ethylene glycol) (PEG) hydrogels hold promise for in vivo applications but induce a foreign body response (F...
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Engineered Cell‐Secreted Extracellular Matrix Modulates Cell Spheroid Mechanosensing and Amplifies their Response to Inductive Cues for the Formation of Mineralized Tissues
Abstract The clinical translation of mesenchymal stromal cell (MSC)-based therapies remains challenging due to rapid cell ...
Advanced Healthcare Materials
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Double‐Network Hydrogel Armored Decellularized Porcine Pericardium as Durable Bioprosthetic Heart Valves
Abstract Heart valve has extraordinary fatigue resistance which beats ∼3 billion times in a lifetime. Bioprosthetic...
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Long‐Term Recruitment of Endogenous M2 Macrophages by Platelet Lysate‐rich Plasma Macroporous Hydrogel Scaffold for Articular Cartilage Defect Repair
Abstract After cartilage damage, a large number of monocytes/macrophages infiltrate into adjacent synovium and the residen...
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Tissue‐like Optoelectronic Neural Interface Enabled by PEDOT:PSS Hydrogel for Cardiac and Neural Stimulation
Abstract Optoelectronic biointerfaces have made a significant impact on modern science and technology from understanding t...
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Ultra‐Rapid Method for Coating Electrochemical Sensors with Antifouling Conductive Nanomaterials Enables Highly Sensitive Multiplexed Detection in Whole Blood
Abstract xxxx. This article is protected by copyright. All rights reserved
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Quenching Epigenetic Drug Resistance Using Anti‐hypoxic Microparticles in Glioblastoma Patient‐derived Chips
Abstract Glioblastoma is one of the most intractable tumor types due to the progressive drug resistance upon tumor mass ex...
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yA Lesion Microenvironment‐Responsive Fungicide Nanoplatform for Crop Disease Prevention and Control
Abstract Controlled fungicide delivery in response to the specific microenvironment produced by fungal pathogens is an adv...
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Au@Ag Nanorods‐PDMS Wearable Mouthguard as A Visualized Detection Platform for Screening Dental Caries and Periodontal Diseases
Abstract The development of an easy-to-use, low-cost, and visualized detection platform for screening human dental caries ...
Advanced Healthcare Materials
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Bacteriophage‐loaded poly(lactic‐co‐glycolic acid) microparticles mitigates Staphylococcus aureus infection and co‐cultures of Staphylococcus aureus and Pseudomonas aeruginosa
Abstract Lung infections caused by Gram-positive Staphylococcus aureus and co-infections caused by S. aureus and Gram-nega...
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Masthead: (Adv. Healthcare Mater. 24/2021)
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Bridging mRNA and Polycation Using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery
Abstract Polyplex for messenger RNA (mRNA) delivery requires strong yet reversible association between mRNA and polycation...
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d‐Amino Acid‐Based Metabolic Labeling Enables a Fast Antibiotic Susceptibility Test of Both Isolated Bacteria and Bronchoalveolar Lavage Fluid
Abstract The threat of multidrug-resistant bacteria has escalated rapidly, increasing the demand for accurate antibiotic s...
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Optimizing Comprehensive Performance of Aggregation‐Induced Emission Nanoparticles through Molecular Packing Modulation for Multimodal Image‐Guided Synergistic Phototherapy
Abstract Fluorescent nanoparticles (NPs) with aggregation-induced emission (AIE) characteristics hold remarkable potential...
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Rational Design of Hydrogel Networks with Dynamic Mechanical Properties to Mimic Matrix Remodeling
Abstract The extracellular matrix (ECM) is a complex, temporally-regulated environment, and engineered hydrogels are incre...
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Photothermal Conjugated Polymer Nanoparticles for Suppressing Breast Tumor Growth by Regulating TRPA1 Ion Channels
Abstract Cancer cells survive by relying on oxidative stress defense against the accumulation of reactive oxygen species (...
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Hydrogel Microparticle‐Templated Anti‐Solvent Crystallization of Small‐Molecule Drugs
Abstract Conventional formulation strategies for hydrophobic small-molecule drug products frequently include mechanical mi...
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Carbon Dots with Intrinsic Bioactivities for Photothermal Optical Coherence Tomography, tumor‐specific Therapy and Postoperative Wound Management
Abstract Carbon dots (CDs) have been considered as promising candidates with superior biocompatibilities for multimodel ca...
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Micro‐/Nanorobots in Antimicrobial Applications: Recent Progress, Challenges, and Opportunities
Abstract The evolution of drug-resistant pathogenic bacteria remains one of the most urgent threats to public health world...
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