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Explainable machine learning model for predicting decline in platelet count after interventional closure in children with patent ductus arteriosus
1 Introduction Patent ductus arteriosus (PDA) is one of the most common congenital heart diseases. Transcatheter closure ...
The association of physical activity and carotid intima-media-thickness in adolescents—data of the prospective early vascular ageing-tyrol cohort study
Introduction Cardio- and cerebrovascular disease (CVD) remains the leading cause of death in Europe with atherosclerosis ...
Editorial: Pediatric infectious diseases and global action plan on AMR
Antimicrobial resistance (AMR) is a critical global health challenge that disproportionately affects pediatric populations...
Griffiths Scales of Child Development 3rd Edition: normalization for the Brazilian population
1 Introduction Child development is complex and dynamic and influenced by numerous factors, intrinsic and extrinsic. Moni...
Functional analysis of a novel homozygous missense IVD gene variant: a case report with dual genetic diagnoses
Introduction Isovaleric acidemia (IVA, OMIM #243500) is an autosomal recessive inborn error of leucine metabolism caused ...
Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumab
Introduction Alopecia areata (AA) is a common form of non-scarring alopecia characterized by acute hair loss in the absen...
Clinical characteristics of hereditary spherocytosis with red blood cell membrane protein gene variants
Introduction Hereditary spherocytosis (HS) is a prevalent genetic disorder characterized primarily by hemolytic anemia, j...
Association of blood manganese and selenium levels with hepatic steatosis among adolescents: a nationwide cross-sectional analysis
1 Introduction Hepatic steatosis has emerged as the most common chronic liver disease in children and adolescents, parall...
Case Report: Cholestatic liver disease in the course of erythropoietic protoporphyria associated with renal hypodysplasia and atrial septal defect
1 Background Erythropoietic protoporphyria (EPP, #177000) along with X-linked protoporphyria (XLP, #300752) represent two...
Comprehensive case report and literature review on perioperative management of multiple pheochromocytoma in a pediatric patient
Comprehensive case report and literature review on perioperative management of multiple pheochromocytoma in a pediatric patient
1 Introduction Pheochromocytomas (PPC) and paragangliomas (PGL) are neuroendocrine tumors originating from the adrenal me...
The vicious spiral in Sudden Infant Death Syndrome
1 SIDS definition The first definition of Sudden Infant Death Syndrome (SIDS) was established during “The Second internat...
Pediatric endoscopic retrograde pancreatography expertise in chronic pancreatitis: a single-center analysis
1 Introduction Chronic pancreatitis (CP) is a distinct pathological entity, not merely a progression from acute pancreati...
Clinical characteristics and risk factors of Clostridioides difficile infection in children with diarrhoea
Introduction Clostridioides difficile (CD) is a specialized anaerobic, grossly gram-positive bacterium transmitted mainly...
Perception of uncertainty concerning illness and coping styles among parents of children with central nervous system tumors: a correlation analysis
Highlights • Central nervous system tumors are the most common solid tumors in children. In this paper, we report an stat...
Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21
Highlights • Epileptic spasms were the first recognized seizure type in all children with trisomy 21. • Children with tri...
Review of rhythm disturbances in patient after fontan completion: epidemiology, management, and surveillance
Introduction The Fontan operation transformed the outlook for children born with a single ventricle. However, it is a fra...
Use of a specialized peptide-based enteral formula containing medium-chain triglycerides for enteral tube feeding in children with cerebral palsy and previous tube feeding intolerance on standard enteral formula: a prospective observational TolerUP study
Introduction Functional feeding disorders and gastrointestinal dysfunction are highly prevalent conditions in children wi...
Increase in methemoglobin fraction due to the use of glyceryl trinitrate patches in preterm infants: a case report and literature review
1 Background The primary role of haemoglobin (Hb) in organisms is to facilitate oxygen transport. This function is ensure...
Investigation of gut microbiota in pediatric patients with peanut allergy in outpatient settings
Introduction Allergic reactions are a common health issue in children, with their incidence rates showing an increasing t...
Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report
Introduction The incidence rate of pulmonary embolism in children has been increasing in recent years. The incidence rate...
Impact of the COVID-19 pandemic on antidepressant and antipsychotic use among children and adolescents: a population-based study
Impact of the COVID-19 pandemic on antidepressant and antipsychotic use among children and adolescents: a population-based study
BackgroundThe COVID-19 pandemic was associated with increases in the prevalence of depression, anxiety and behavioural pro...
The risk of pediatric cardiovascular diseases in offspring born to mothers with systemic lupus erythematosus: a nationwide study
The risk of pediatric cardiovascular diseases in offspring born to mothers with systemic lupus erythematosus: a nationwide study
BackgroundSystemic lupus erythematosus (SLE), a common autoimmune disease predominantly affecting women, has been linked t...
A prospective observational study of nurses performing minimally invasive tissue sampling of brain, liver, and lung tissues among deceased neonates and stillbirths in Ethiopia
A prospective observational study of nurses performing minimally invasive tissue sampling of brain, liver, and lung tissues among deceased neonates and stillbirths in Ethiopia
BackgroundWith a neonatal mortality rate of 33 per 1,000 live births in 2019, Ethiopia is striving to attain the Sustainab...
Pediatric renal lithiasis in Spain: research, diagnostic and therapeutic challenges, and perspectives
Pediatric renal lithiasis in Spain: research, diagnostic and therapeutic challenges, and perspectives
Incidence and prevalence of urolithiasis is apparently increasing worldwide, also among children and adolescents. Neverthe...
Butyrate suppresses experimental necrotizing enterocolitis–induced brain injury in mice
Butyrate suppresses experimental necrotizing enterocolitis–induced brain injury in mice
BackgroundNecrotizing enterocolitis (NEC) is a devastating disease in premature infants, and 50% of infants with surgical ...
Advancing early relational health: a collaborative exploration of a research agenda
Advancing early relational health: a collaborative exploration of a research agenda
Here, we introduce the Early Relational Health (ERH) Learning Community's bold, large-scale, collaborative, data-drive...
Approach to multidrug resistant infections in pediatric transplant recipients
Approach to multidrug resistant infections in pediatric transplant recipients
IntroductionThere is increasing recognition of infections due to multidrug-resistant Gram negative (MDRGN) bacterial infec...
A bibliometric analysis of chemotherapy and pain in pediatric patients over the last decade
A bibliometric analysis of chemotherapy and pain in pediatric patients over the last decade
BackgroundChemotherapy is an important treatment for children with cancer, and chemotherapy-induced pain is an important r...
Case Report: Acute abdomen and large mesenteric mass as another face of multisystem inflammatory syndrome in an adolescent child: measure twice, act once!
Case Report: Acute abdomen and large mesenteric mass as another face of multisystem inflammatory syndrome in an adolescent child: measure twice, act once!
IntroductionDuring the Covid-19 era, acute abdomen and mesenteric lymphadenopathy were encountered as frequent mimic of ap...
A single scalp nodule as the first presentation of acute lymphoblastic leukemia (KMT2A::MLLT3) in a healthy-appearing infant: a case report
A single scalp nodule as the first presentation of acute lymphoblastic leukemia (KMT2A::MLLT3) in a healthy-appearing infant: a case report
BackgroundInfant leukemia is a rare form of acute leukemia diagnosed prior to the age of 1 and is characterized by an extr...
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