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Reducing the environmental impact of healthcare to improve health, sustainability and equity
Reducing the environmental impact of healthcare to improve health, sustainability and equity
As the impacts of climate change and the transgression of other planetary boundaries on human health become evident, so is...
Can the HEARTS initiative reduce the burden of cardiovascular disease?
Can the HEARTS initiative reduce the burden of cardiovascular disease?
What is HEARTS?Cardiovascular disease (CVD) continues to exert a heavy burden in most countries in the world, with high bl...
A call for community-shared decisions
A call for community-shared decisions
Shared decision-making in medicine is widely viewed as a collaboration between the patient and the clinician. For example,...
Do infographics 'spin the findings of health and medical research?
Do infographics 'spin the findings of health and medical research?
WHAT IS ALREADY KNOWN ON THIS TOPICMany infographics summarising health and medical research do not report sufficient info...
Safety implications of mask use: a systematic review and evidence map
Safety implications of mask use: a systematic review and evidence map
WHAT IS ALREADY KNOWN ON THIS TOPICPrior research on the effects of face masks on physiological, cognitive and psychologic...
Rapid review method series: interim guidance for the reporting of rapid reviews
Rapid review method series: interim guidance for the reporting of rapid reviews
WHAT IS ALREADY KNOWN ON THIS TOPICRapid review (RR) conduct stems from the systematic review process but has unique consi...
Peer reviewers conflicts of interest in biomedical research: scoping review
Peer reviewers conflicts of interest in biomedical research: scoping review
AbstractBackground Peer review may improve the quality of research manuscripts and aid in editorial decisions, but reviewe...
Ten recommendations to foster healthcare resource stewardship in knowledge translation
Ten recommendations to foster healthcare resource stewardship in knowledge translation
Providing healthcare services with little to no benefit represents an important issue in healthcare worldwide. It is estim...
Strengthening transparency in randomised trials related to multimorbidity: key points and recommendations to guide reporting
Strengthening transparency in randomised trials related to multimorbidity: key points and recommendations to guide reporting
Multimorbidity, defined by the WHO as the coexistence of two or more chronic conditions,1 is a growing challenge for publi...
Stop searching and you will find it: Search-Resistant Concepts in systematic review searches
Stop searching and you will find it: Search-Resistant Concepts in systematic review searches
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSThis paper suggests the new term search-resistant concepts for conc...
Simple tool implementing Buchers method for indirect treatment comparisons in meta-analyses
Simple tool implementing Buchers method for indirect treatment comparisons in meta-analyses
StandfirstHealthcare practitioners and patients are often required to make choices between two treatment options which may...
Approach of patient involvement in systematic review development
Approach of patient involvement in systematic review development
We are writing regarding our approach to involving patients in a systematic review (SR) with component network meta-analys...
Hurdles of trying to avoid low-value care: two cheers for Choosing Wisely
Hurdles of trying to avoid low-value care: two cheers for Choosing Wisely
I learnt about Choosing Wisely in the USA from reporting at its inception and followed its progress with great interest. I...
Overdiagnosis and Barretts oesophagus: a call for clarity
Overdiagnosis and Barretts oesophagus: a call for clarity
This paper examines three varied ways in which the notion of overdiagnosis has been employed in literature on Barrett’s oe...
Is a one-size-fits-all '12-month rule appropriate when it comes to the last search date in systematic reviews?
Is a one-size-fits-all '12-month rule appropriate when it comes to the last search date in systematic reviews?
SRs are a recognised research approach for identifying, synthesising and analysing published evidence on topics of interes...
Expanding the measurement of overdiagnosis in the context of disease precursors and risk factors
Expanding the measurement of overdiagnosis in the context of disease precursors and risk factors
Because individual patients weigh benefits and harms differently, it is important to provide quantitative information abou...
Living health technology assessments: how close to living reality?
Living health technology assessments: how close to living reality?
IntroductionHealthcare decision-makers are exploring more responsive, innovative processes in the wake of the COVID-19 pan...
Detection bias in open-label trials of anticancer drugs: a meta-epidemiological study
Detection bias in open-label trials of anticancer drugs: a meta-epidemiological study
are validated by studies that overcome this limitation, it is desirable to establish central reviewers in oncological open...
Piloting a new method to estimate action thresholds in medicine through intuitive weighing
Piloting a new method to estimate action thresholds in medicine through intuitive weighing
IntroductionThe threshold approach in clinical decision-makingWhen confronted with diagnostic uncertainty clinicians will ...
Re-evaluating the role of pilot trials in informing effect and sample size estimates for full-scale trials: a meta-epidemiological study
Re-evaluating the role of pilot trials in informing effect and sample size estimates for full-scale trials: a meta-epidemiological study
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Cleara...
Bias, quality and reporting in health research: differences and tools for appraisal
Bias, quality and reporting in health research: differences and tools for appraisal
Bias is generally defined as a systematic error or deviation from the truth in research results, which leads to underestim...
Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial
Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial
IntroductionFunctional dyspepsia is a frequently occurring disorder that can be caused by a variety of factors, with no ev...
Rapid reviews methods series: Guidance on literature search
Rapid reviews methods series: Guidance on literature search
WHAT IS ALREADY KNOWN ON THIS TOPICCompared with systematic reviews, rapid reviews (RR) often abbreviate or limit the lite...
Catalogue of bias: novelty bias
Catalogue of bias: novelty bias
Novelty bias is the tendency for an intervention to appear better when it is new. It is also known as the ‘novel agent eff...
How caring for my child with cancer changed my approach to clinical care and research
How caring for my child with cancer changed my approach to clinical care and research
I am a clinical psychologist who specialises in helping children with medical illnesses and their families. I am also a mo...
Rapid reviews methods series: Guidance on team considerations, study selection, data extraction and risk of bias assessment
Rapid reviews methods series: Guidance on team considerations, study selection, data extraction and risk of bias assessment
WHAT IS ALREADY KNOWN ON THIS TOPICCompared with full systematic reviews, rapid reviews (RRs) often omit dual processes or...
Relationship between the conflicts of interest and the results of meta-analyses of homoeopathy trials
Relationship between the conflicts of interest and the results of meta-analyses of homoeopathy trials
In the absence of robust trials supporting the efficacy of homoeopathy, people who criticise or, on the contrary, defend h...
Exploring advanced methods for network meta-analysis
Exploring advanced methods for network meta-analysis
High-quality systematic reviews (SRs) of both new and existing health technologies are vital to inform clinical practices ...
What is the place in therapy for nirmatrelvir/ritonavir?
What is the place in therapy for nirmatrelvir/ritonavir?
The COVID-19 pandemic presents substantial challenges for governments and providers keen to provide effective treatments. ...
Metro Mapping: development of an innovative methodology to co-design care paths to support shared decision making in oncology
Metro Mapping: development of an innovative methodology to co-design care paths to support shared decision making in oncology
Shared decision making and service designTreatment decision-making can be complex, notably when there are multiple treatme...
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