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The relationship between co-use of tobacco and alcohol and cognitive decline in middle-aged and older Chinese males: A cross-lagged panel network analysis
According to the World Health Organization (World Health Organization, 2024), the global population aged 60 and over will ...
Trends in perceived harmfulness of tobacco, alcohol, and cannabis and its’ use in 12–16-year-olds, from 2003 to 2023
BackgroundSubstance use is bidirectionally related to perceived harmfulness of its use. While adolescent tobacco, alcohol,...
Comparing random forest and elastic net models to predict substance use disorder transitions in participants with cannabis and stimulant use: Evidence from the All of Us cohort
The data used in this work come from the All of Us Research Program Registered Tier dataset (version 8), accessible throug...
The association between benzodiazepine proliferation in the unregulated drug supply and experiences of violence: A gender-based analysis
Over the last decade, the unregulated drug supply in North America has become increasingly unpredictable and contaminated ...
Reciprocal relationships among youth social media use, internalizing symptoms, and substance use
Volume 278, 1 January 2026, 113018Author links open overlay panel, , , , , Highlights•Youth social media use, mental healt...
Driving after cannabis consumption among US adults ages 50 years and older: A short communication
Cannabis-impaired driving is a public health concern that is under-investigated in subpopulations, such as middle and olde...
Access to medications for opioid use disorder among primary care patients with homeless experience in the Department of Veterans Affairs
Opioids continue to drive drug-related morbidity and mortality (Zhang et al., 2024) particularly among persons with experi...
Evaluation of suvorexant effects on alcohol seeking and self-administration in baboons
In 2023, 28.9 million Americans aged 12 or older qualified as having alcohol use disorder (AUD) (American Psychiatric Asso...
Longitudinal study of smoking cessation among World Trade Center Health Registry enrollees, 2003–2021
Over the past several decades, the use of combustible cigarettes (hereafter referred to as “smoking”) in the United States...
Is cannabis legalization associated with treatment completion? A study of pregnant women admitted for cannabis use in substance use treatment facilities, 2020–2022
Cannabis is the most commonly used illicit substance during pregnancy in the United States (U.S.) (Substance Abuse and Men...
Use of Gabapentin With or Without a Prescription in Substance Use Treatment Settings: A National Analysis of Urine Drug Testing Data, 2016-2023
Gabapentin is an oral anticonvulsant approved by the United States Food and Drug Administration (FDA) as an adjunctive tre...
Leveraging a Digital Health Intervention to Improve Recovery Outcomes Among People with Substance Misuse Experiencing Housing Insecurity
Available online 3 January 2026, 113022Author links open overlay panel, , , , , , , Highlights•Housing insecurity increase...
Effects of acute adolescent stress on the acquisition and maintenance of intravenous oxycodone self-administration in male and female rats
The opioid epidemic is an increasing threat to public health, with opioid-involved overdose fatalities surpassing 81,000 i...
Explainable Machine Learning for Predicting Opioid-Related Aberrant Behavior: A Multimodal Approach Using Clinical Text and Structured Data
Opioid overdose is now one of the most concerning public health crises of the 21st century, with a sharp increase in misus...
Test-Retest Reliability of mgTHC consumption in the self-administered Cannabis Exposure Index (CEI)
The U.S. cannabis landscape has changed dramatically (e.g., increasing state legalization; products with high delta-9-tetr...
Developmental Windows of Vulnerability: Substance-Specific Effects of Prenatal Exposure Timing on Child Psychopathology
Prenatal substance exposure, encompassing alcohol, tobacco, and cannabis, represents a significant and preventable risk fa...
Impact of Metabolic Syndrome Components on Fibrosis Severity and Mortality in Alcohol-Related Liver Disease
ABASSA Kodjo Kunale: Writing – original draft, Validation, Software, Methodology, Formal analysis, Data curation, Conceptu...
Inequities in blunt use across multiple socio-demographic intersections among US adults
Volume 279, 1 February 2026, 113019Author links open overlay panel, , , Highlights•Blunt use was most prevalent among adul...
Are there differences in gradual versus abrupt smoking cessation quit attempts and success by social grade? A population study in England
Background and aimsSmoking rates remain higher among individuals from less advantaged social grades, who tend to be less s...
Association of tobacco and other substance use with nicotine pouch awareness and use in US adolescents
Nicotine pouches (NP, i.e., sachets containing microcrystalline cellulose, nicotine, flavorings, and other additives, whic...
Characteristics associated with forced treatment discontinuation among people who use drugs in Rhode Island
While substance use disorder (SUD) treatment substantially improves health outcomes among people who use drugs, SUD treatm...
Patterns of past month cannabis consumption and cannabis use disorder – Insights from a nationally representative survey
Cannabis use is on the rise across the United States, with 38 states legalizing medical cannabis use and 23 states legaliz...
Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice
Opioid overdose fatalities have sharply accelerated in the US in the 21st century, and the specific substances involved in...
Substance-induced mental disorders and discontinuation of medication for opioid use disorder
Mental health conditions and substance use disorders (SUDs) commonly present as co-occurring conditions (Wilson et al., 20...
Harms associated with prescription drug misuse in Ireland: A national observational study of trends in treatment demand, non-fatal intentional drug overdoses and drug related deaths 2010–2020
AimsTo describe the health-related harms associated with the misuse of benzodiazepines/z-drugs, prescription opioids, gaba...
Using a loose-leaf vaporizer to study tobacco-cannabis co-administration: A proof-of-concept study
Cannabis containing Δ-9-tetrahydrocannabinol (referred in this manuscript as cannabis) is the most frequently used federal...
A within-subject cross-over trial comparing the acute effects of vaporized delta-8-tetrahydrocannabinol and delta-9-tetrahydrocannabinol in healthy adults
The 2018 Agricultural Improvement Act (or “Farm Bill”) removed hemp (cannabis with ≤0.3 % Δ9-tetrahydrocannabinol, Δ9-THC)...
Self-underestimation of BAC as a predictor of risky driving in heavy drinkers
Alcohol-related driving fatalities persist as a public health issue in the United States. Although the trends regarding dr...
Telehealth tDCS to reduce cannabis use: A pilot RCT in multiple sclerosis as a framework for generalized use
IntroductionCannabis use is rising in the United States. Up to 30 % of individuals who use cannabis develop cannabis use d...
Spatial epidemiology of nonfatal overdose in a community-based cohort of marginalized women in Vancouver, British Columbia (2014–2022)
Volume 272, 1 July 2025, 112670Author links open overlay panel, , , , , , Highlights•Marginalized women face a high and ri...
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