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Blocking Aldosterone Synthesis: Whose BrigHTN Idea Was That?
Blocking Aldosterone Synthesis: Whose BrigHTN Idea Was That?
In the pursuit of BP-lowering therapies, few investigations have been as fruitful as efforts to thwart the renin-angiotens...
HRSA Pushes OPTN Reforms as Criticism of US Organ Transplantation System Increases
HRSA Pushes OPTN Reforms as Criticism of US Organ Transplantation System Increases
Congress passed the 1984 National Organ Transplant Act to unify organ donation, recovery, and allocation. Blaming a system...
Facility Closures and Distance Traveled to Receive Dialysis Care in the United States
Facility Closures and Distance Traveled to Receive Dialysis Care in the United States
1Section of Nephrology, Baylor College of Medicine, Houston, Texas 2Section of Epidemiology and Population Sc...
Interstitial Eosinophilic Aggregates and Kidney Outcome in Patients with CKD
Interstitial Eosinophilic Aggregates and Kidney Outcome in Patients with CKD
Background Interstitial eosinophilic aggregates are observed in various kidney diseases, but thei
Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy
Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy
Background IgA nephropathy is the most common primary GN worldwide, with dominant deposition of I
Pregnancy and Family Policies in Nephrology Fellowships
Pregnancy and Family Policies in Nephrology Fellowships
1Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina School of Medicine, ...
Obinutuzumab in Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome in Children
Obinutuzumab in Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome in Children
Background B-cell depletion with rituximab induces sustained remission in children with steroid-d
Cystatin C–Based eGFR Changes during Gender-Affirming Hormone Therapy in Transgender Individuals
Cystatin C–Based eGFR Changes during Gender-Affirming Hormone Therapy in Transgender Individuals
Background Men with CKD tend to experience a faster eGFR decline than women, potentially because
System-Level Strategies to Improve Home Dialysis: Policy Levers and Quality Initiatives
System-Level Strategies to Improve Home Dialysis: Policy Levers and Quality Initiatives
Advocacy and policy change are powerful levers to improve quality of care and better support patient
Vascular Access–Related Distal Ischemia Requiring Intervention: Frequency, Risk Factors, and Consequences
Vascular Access–Related Distal Ischemia Requiring Intervention: Frequency, Risk Factors, and Consequences
Background Distal ischemia is a rare complication in patients undergoing placement of an arteriov
Characteristics of Complement Protein Deposition in Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition
Characteristics of Complement Protein Deposition in Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition
Background Hypocomplementemia and complement co-deposition with monoclonal immunoglobulins in glo
Nurse Practitioner Care Compared with Primary Care or Nephrologist Care in Early CKD
Nurse Practitioner Care Compared with Primary Care or Nephrologist Care in Early CKD
Background Early interventions in CKD have been shown to improve health outcomes; however, gaps i
Physician Preferences when Selecting Candidates for Lower-Quality Kidney Offers
Physician Preferences when Selecting Candidates for Lower-Quality Kidney Offers
Background In the United States, more than 50% of kidneys in the lowest 15% quality range (those
How I Treat Tumor Lysis Syndrome
How I Treat Tumor Lysis Syndrome
1Department of medical intensive care unit, Saint-Louis Hospital, Assistance Publique-Hôpitaux de Paris, University...
Does Gender-Affirming Hormone Therapy Affect the Kidney?
Does Gender-Affirming Hormone Therapy Affect the Kidney?
1Chronic Disease Innovation Centre, Seven Oaks General Hospital, Winnipeg, Manitoba, Canada 2Max Rady Departm...
Treating Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome: To Obi or Not to Obi, That is the Question
Treating Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome: To Obi or Not to Obi, That is the Question
1Division of Nephrology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada ...
Dialysis Vascular Access and Critical Distal Ischemia
Dialysis Vascular Access and Critical Distal Ischemia
1Department of Medicine, John D. Dingell Veterans Affairs Medical Center, Wayne State University School of Medicine...
Physician Preferences for Lower-Quality Kidney Offers
Physician Preferences for Lower-Quality Kidney Offers
On August 16, 2023, I celebrated my 1-year kidney transplant anniversary. My CKD was due to AA amyloidosis disease, which ...
Maximizing Utility of Deceased Donor Kidney Offers
Maximizing Utility of Deceased Donor Kidney Offers
Division of Nephrology, Stanford University, Palo Alto, California Correspondence: Dr. Jillian S. Caldwell, D...
Right-Sizing Multiorgan Allocation Involving Kidneys
Right-Sizing Multiorgan Allocation Involving Kidneys
Organ transplants save lives and improve quality of life for patients who receive them.1 Along with recognizing these bene...
Race-Free Creatinine-Based Estimation of GFR and Projection of CKD to 2060 in the United States
Race-Free Creatinine-Based Estimation of GFR and Projection of CKD to 2060 in the United States
1Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 2Divis...
Racial and Ethnic Disparities and Facility-Level Variation in GLP-1 RA Prescription among US Veterans with CKD
Racial and Ethnic Disparities and Facility-Level Variation in GLP-1 RA Prescription among US Veterans with CKD
1Section of Nephrology, Baylor College of Medicine, Selzman Institute for Kidney Health, Houston, Texas 2Rese...
Increased Access, Persistent Disparities: Trends in Disparities in Peritoneal Dialysis (PD) Use, 2009–2019
Increased Access, Persistent Disparities: Trends in Disparities in Peritoneal Dialysis (PD) Use, 2009–2019
Peritoneal dialysis (PD) use has increased in the United States since 2009, but how this has affecte
Differences in the Circulating Proteome in Individuals with versus without Sickle Cell Trait
Differences in the Circulating Proteome in Individuals with versus without Sickle Cell Trait
Background Sickle cell trait affects approximately 8% of Black individuals in the United States,
Fixed-Dose Combination Therapy for the Prevention of Cardiovascular Diseases in CKD: An Individual Participant Data Meta-Analysis
Fixed-Dose Combination Therapy for the Prevention of Cardiovascular Diseases in CKD: An Individual Participant Data Meta-Analysis
Background Fixed-dose combination treatments reduce cardiovascular disease in primary prevention.
Changes in Bone Quality after Treatment with Etelcalcetide
Changes in Bone Quality after Treatment with Etelcalcetide
Introduction Secondary hyperparathyroidism is associated with osteoporosis and fractures. Etelcal
Prostaglandin E2, Osmoregulation, and Disease Progression in Autosomal Dominant Polycystic Kidney Disease
Prostaglandin E2, Osmoregulation, and Disease Progression in Autosomal Dominant Polycystic Kidney Disease
Background Prostaglandin E2 (PGE2) plays a physiological role in osmoregulation, a process that i
Comparison of Short-Term Outcomes in Kidney Transplant Recipients from SARS-CoV-2–Infected versus Noninfected Deceased Donors
Comparison of Short-Term Outcomes in Kidney Transplant Recipients from SARS-CoV-2–Infected versus Noninfected Deceased Donors
Background Acceptable post-transplant outcomes were reported in kidney transplant recipients from
Setting Up Home Dialysis Programs: Now and in the Future
Setting Up Home Dialysis Programs: Now and in the Future
Home dialysis utilization has been growing in the United States over the past decade but still lags
Rare Variants in Complement Gene in C3 Glomerulopathy and Immunoglobulin-Mediated Membranoproliferative GN
Rare Variants in Complement Gene in C3 Glomerulopathy and Immunoglobulin-Mediated Membranoproliferative GN
Background C3 glomerulopathy and idiopathic immunoglobulin-mediated membranoproliferative GN (Ig-
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