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Immune and inflammation‐related gene polymorphisms and susceptibility to tuberculosis in Southern Xinjiang population: A case‐control analysis
Immune and inflammation‐related gene polymorphisms and susceptibility to tuberculosis in Southern Xinjiang population: A case‐control analysis
Abstract Genetic and immune factors play an important role in tuberculosis. Under different ethnicities and genetic backgr...
The importance of establishing genetic phase in clinical medicine
The importance of establishing genetic phase in clinical medicine
Abstract Haplotyping or determination of genetic phase has always played a pivotal role in MHC (HLA studies) both in helpi...
Systematic review of associations between HLA and renal function
Systematic review of associations between HLA and renal function
Abstract Introduction Kidney dysfunction is a highly significant disease, both in the United Kingdom and globally. Many pr...
ELISpot assay and prediction of organ transplant rejection
ELISpot assay and prediction of organ transplant rejection
Abstract The ELISpot assay is a sensitive technique applied to assess cytokine-producing memory/effector T cells and human...
Human leukocyte antigen epitope mismatch loads and the development of de novo donor‐specific antibodies in cardiothoracic organ transplantation
Human leukocyte antigen epitope mismatch loads and the development of de novo donor‐specific antibodies in cardiothoracic organ transplantation
Abstract De novo donor-specific human leucocyte antigen (HLA) antibodies (dnDSA) are associated with increased risk of rej...
Association analysis of MALAT1 polymorphisms and risk of psoriasis among Iranian patients
Association analysis of MALAT1 polymorphisms and risk of psoriasis among Iranian patients
Abstract MALAT1 is a long non-coding transcript that affects immune reactions, thus being involved in the pathoaetiology o...
Immunological drivers of IgA nephropathy: Exploring the mucosa–kidney link
Immunological drivers of IgA nephropathy: Exploring the mucosa–kidney link
Abstract IgA nephropathy (IgAN) is the most common pattern of primary glomerular disease reported worldwide. Up to 40% of ...
IL1R2 polymorphisms and their interaction are associated with osteoporosis susceptibility in the Chinese Han population
IL1R2 polymorphisms and their interaction are associated with osteoporosis susceptibility in the Chinese Han population
Abstract Aims Interleukin 1 (IL-1) inhibitory receptor type 2 (IL1R2) serves as a negative regulator of IL-1 signalli...
A comment on estimating HLA haplotype frequencies from homozygous individuals
A comment on estimating HLA haplotype frequencies from homozygous individuals
Early View LETTER TO THE EDITOR José Manuel Nunes, Corresponding Author ...
Should results of HLA haplotype frequency estimations be normalized?
Should results of HLA haplotype frequency estimations be normalized?
Dear Editor, regarding the comment by Nunes (Nunes, 2021) on our publication ‘Estimating HLA haplotype ...
The polymorphism of HLA‐A, ‐C, ‐B, ‐DRB3/4/5, ‐DRB1, ‐DQB1 loci in Zhejiang Han population, China using NGS technology
The polymorphism of HLA‐A, ‐C, ‐B, ‐DRB3/4/5, ‐DRB1, ‐DQB1 loci in Zhejiang Han population, China using NGS technology
Abstract The distributions of HLA allele and haplotype are various in the populations. Currently, the data for HLA alleles...
Association analysis of B7‐H3 and B7‐H4 gene single nucleotide polymorphisms in susceptibility to ankylosing spondylitis in eastern Chinese Han population
Association analysis of B7‐H3 and B7‐H4 gene single nucleotide polymorphisms in susceptibility to ankylosing spondylitis in eastern Chinese Han population
Abstract This study was conducted to describe the association between the genetic variation of the recently identified imm...
BSHI/BTS guidance on crossmatching before deceased donor kidney transplantation
BSHI/BTS guidance on crossmatching before deceased donor kidney transplantation
Abstract All UK H&I laboratories and transplant units operate under a single national kidney offering policy, but there ha...
Estimating HLA haplotype frequencies from homozygous individuals – A Technical Report
Estimating HLA haplotype frequencies from homozygous individuals – A Technical Report
Abstract We estimated HLA haplotype frequencies based on individuals homozygous for 4, 5 or 6 loci. Validation of our...
Approaches for the characterization of clinically relevant pre‐transplant human leucocyte antigen (HLA) antibodies in solid organ transplant patients
Approaches for the characterization of clinically relevant pre‐transplant human leucocyte antigen (HLA) antibodies in solid organ transplant patients
Abstract The avoidance of antibody-mediated rejection (AMR) attributed to human leucocyte antigen (HLA) antibody incompati...
A comparison of immune receptor recombination databases sourced from tumour exome or RNAseq files: Verifications of immunological distinctions between primary and metastatic melanoma
A comparison of immune receptor recombination databases sourced from tumour exome or RNAseq files: Verifications of immunological distinctions between primary and metastatic melanoma
Abstract It became apparent several years ago that RNAseq and exome files prepared from tissue could be mined for adaptive...
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