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Synergistic strategy for high-yield 2,3-butanediol and acetoin production in Bacillus licheniformis MW03 based on metabolic engineering
B. licheniformis is widely used in industrial production due to its efficient secretion system and broad metabolic capacit...
Optimizing Chlorella vulgaris production and exploring its impact on germination through microalga-N2-fixing bacteria consortia
Microalgal biomass is increasingly valued in industrial and agricultural sectors due to its bioactive compounds. However, ...
Enhancement of natamycin production in Streptomyces gilvosporeus through heavy ion beam mutagenesis and global transcription machinery engineering
Natamycin is a polyene macrolide antibiotic with a 26-membered lactone ring, which contains conjugated double bonds. This ...
Komagataella phaffii as a microbial cell factory for antimicrobial peptide production
Antimicrobial peptides (AMPs), from both natural and synthetic sources, can be a viable alternative for the treatment of b...
Characterization of Single Cell Protein produced by Cupriavidus necator grown on various nitrogen and carbon sources
Microorganisms can serve as Single Cell Proteins (SCP) used as an alternative and non-conventional protein source to meet ...
Performance of a pilot scale pressurized deep-jet gas bioreactor for SCP production with Cupriavidus necator H16
Global warming and climate change are some of the greatest challenges human society is facing (Rawat et al., 2024, Bevacqu...
Microalgae in 3D bioprinting and bone regeneration: Trends, applications, and future perspectives
Microalgae have increasingly come into focus as multifunctional biological resources, offering significant promise in rege...
Chitosan application in cosmetics and dermatology – Antimicrobial and prebiotic potential to control human microbiome
Polymers have become indispensable materials in modern industries due to their versatile physicochemical properties and tu...
Preparation of high-purity 1,3-distearoyl-2-oleoylglycerol (StOSt) via a two-step enzymatic interesterification combined with two-step solvent fractionation
Cocoa butter (CB), an essential fat in chocolate production, is derived from cacao beans. CB is composed mainly of 1,3-dip...
Improving thermostability of α-L-fucosidase from Pedobacter sp. via consensus-guided engineering and directed evolution
Human milk oligosaccharides (HMOs) represent the third most abundant components in human milk, following lactose and lipid...
Seaweed-derived biostimulants for sustainable crop production: A review
The increasing concerns over climate changes and environmental impacts of synthetic agrochemicals have led to a growing in...
High-concentration Mg2+ stress improves L-lactic acid biosynthesis of Bacillus coagulans revealed by combined analysis of transcriptome and metabolome
L-lactic acid (L-LA), a naturally occurring organic acid, has extensive applications in the food, pharmaceutical, textile,...
Enhanced interfacial microbial degradation of n-hexane-contaminated waste gas using a novel magnetic silicone oil
Volatile organic compounds (VOCs) are key precursors in the formation of PM2.5 and ozone (O3), playing a critical role in ...
Beyond tyrosine feeding: A novel fed-batch cultivation strategy based on tyrosine metabolic engineering in recombinant CHO cells
Chinese hamster ovary (CHO) cells serve as the predominant host for monoclonal antibody (mAb) production in biopharmaceuti...
Bioconversion for ursodeoxycholic acid using β-cyclodextrin included-chenodeoxycholic acid via immobilized cells of Xanthomonas maltophilia
Ursodeoxycholic acid (UDCA) is a clinically used drug which has a long history of practice in prevention and treatment of ...
CRISPR/Cas9-based gene deletion and targeted metabolomics reveal ectoine flux reprogramming in Halomonas campaniensis
Ectoine (1,4,5,6-tetrahydro–2-methyl-4-pyrimidinecarboxylic acid) and its derivatives are compatible solutes produced intr...
Construction of high protein-producing mutant yeast strains via point and structural mutageneses and their use for carotenoid production
Yeast Saccharomyces cerevisiae is a microorganism widely used in the industrial field as a production platform for protein...
Rational comparison of biohydrogen production using Clostridium species through dark fermentation during anaerobic batch processes
It is widely admitted that hydrocarbon combustion is a major source of greenhouse gas emissions, contributing to climate c...
Impact of humanization scaffold design on the functional activity of FGFR2-targeting chicken scFvs
Fibroblast growth factor receptor 2 (FGFR2), a member of the FGFR family of receptor tyrosine kinases, plays a central rol...
Efficient CRISPR/Cas-based gene editing in cotton induced by cotton leaf crumple virus
Genetic mutations and natural variations are the basis for analysis of crop gene function and underlie the formation of im...
Laboratory Evolution and Characterization of Nitrate-Resistant Phosphite Dehydrogenase (PtxD) for Enhanced Cyanobacterial Cultivation
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Targeted Inhibition of Oral Biofilm Formation Using Phage-Derived High-Affinity Peptides
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A novel directed evolution approach for co-evolution of β-glucosidase activity and organic acid tolerance
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A robust scale-down model development and process characterization for monoclonal antibody biomanufacturing using multivariate data analysis
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Identification of a sucrose phosphorylase variant from Streptococcus mutans for production of epigallocatechin gallate glucosides
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Optimization of fungal fermentation for the extraction of polyphenols from Flourensia cernua and its effect on cellular metabolism
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Efficiently scaled-up production of recombinant human elastin-like polypeptides using multiple optimization strategies
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Dark septate endophytic fungus Alternaria sp. 17463 regulates various antioxidant enzymes and compounds to mitigate salt stress caused by different anion salts.
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The promoter of Zymomonas mobilis respiratory NADH dehydrogenase (ndh) is induced by oxygen
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Long-term bioreactor cultivation affects dioscin content and the ratio of 25(S)- and 25(R)-protodioscin isomers in the suspension cell culture of Dioscorea deltoidea Wall
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