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Locations of membrane protein production in a cyanobacterium
Locations of membrane protein production in a cyanobacterium
ABSTRACT Cyanobacteria show an unusually complex prokaryotic cell structure including a distinct intracytoplasmic membrane...
Bacterial bioconvection confers context-dependent growth benefits and is robust under varying metabolic and genetic conditions
Bacterial bioconvection confers context-dependent growth benefits and is robust under varying metabolic and genetic conditions
ABSTRACTMicrobes often respond to environmental cues by adopting collective behaviors—like biofilms or swarming—that benef...
Identification of Streptococcus pneumoniae genes associated with hypothiocyanous acid tolerance through genome-wide screening
Identification of Streptococcus pneumoniae genes associated with hypothiocyanous acid tolerance through genome-wide screening
ABSTRACT Streptococcus pneumoniae is a commensal bacterium and invasive pathogen that causes millions of deaths worldwide....
Bacteriophage steering of Burkholderia cenocepacia toward reduced virulence and increased antibiotic sensitivity
Bacteriophage steering of Burkholderia cenocepacia toward reduced virulence and increased antibiotic sensitivity
ABSTRACT Antibiotic resistance in bacteria is a growing global concern and has spurred increasing efforts to find alternati...
The Caulobacter NtrB-NtrC two-component system bridges nitrogen assimilation and cell development
The Caulobacter NtrB-NtrC two-component system bridges nitrogen assimilation and cell development
ABSTRACT A suite of molecular sensory systems enables Caulobacter to control growth, development, and reproduction in resp...
Expression of RcrB confers resistance to hypochlorous acid in uropathogenic Escherichia coli
Expression of RcrB confers resistance to hypochlorous acid in uropathogenic Escherichia coli
ABSTRACTTo eradicate bacterial pathogens, neutrophils are recruited to the sites of infection, where they engulf and kill ...
Extracellular DNA enhances biofilm integrity and mechanical properties of mucoid Pseudomonas aeruginosa
Extracellular DNA enhances biofilm integrity and mechanical properties of mucoid Pseudomonas aeruginosa
ABSTRACT Pseudomonas aeruginosa is one of the most common biofilm-forming pathogens responsible for lung infections of ind...
From regulation to ruin: a rogue sigma factor causes cell death in Bacillus subtilis
From regulation to ruin: a rogue sigma factor causes cell death in Bacillus subtilis
ABSTRACTA rogue, plasmid-encoded sigma factor that kills Bacillus subtilis is the focus of a new study by A. T. Burton, D....
The biofilm community resurfaces: new findings and post-pandemic progress
The biofilm community resurfaces: new findings and post-pandemic progress
ABSTRACTThe ninth American Society for Microbiology Conference on Biofilms was convened in-person on 13–17 November 2022 i...
Double-anonymous peer review comes to JB
Double-anonymous peer review comes to JB
Käsmann L, Schröder A, Frey B, Fleischmann DF, Gauer T, Ebert N, Hecht M, Krug D, Niyazi M, Mäurer M, Young DEGRO Group. 2...
A coating of lipoproteins provides a stabilizing environment on the inner membrane of Bacillus subtilis spores
A coating of lipoproteins provides a stabilizing environment on the inner membrane of Bacillus subtilis spores
ABSTRACT A new study by M. J. Flores, K. Duricy, S. Choudhary, M. Laue, and D. L. Popham (J Bacteriol 205:e00142-23, 2023,...
The alternative sigma factor SigN of Bacillus subtilis is intrinsically toxic
The alternative sigma factor SigN of Bacillus subtilis is intrinsically toxic
ABSTRACT Sigma factors bind and direct the RNA polymerase core to specific promoter sequences, and alternative sigma facto...
Expanding our grasp of two-component signaling in Clostridioides difficile
Expanding our grasp of two-component signaling in Clostridioides difficile
ABSTRACT The intestinal pathogen Clostridioides difficile encodes roughly 50 TCS, but very few have been characterized in ...
Mutations in the C-terminal region of the bacteriophage exclusion protein PglX can selectively inactivate restriction in Salmonella
Mutations in the C-terminal region of the bacteriophage exclusion protein PglX can selectively inactivate restriction in Salmonella
ABSTRACT Salmonella enterica serovar Typhimurium strain LT2 is protected by two DNA restriction-modification systems (HsdR...
TamAB is regulated by PhoPQ and functions in outer membrane homeostasis during Salmonella pathogenesis
TamAB is regulated by PhoPQ and functions in outer membrane homeostasis during Salmonella pathogenesis
ABSTRACT Salmonella survive and replicate in macrophages, which normally kill bacteria by exposing them to a variety of ha...
Proteomic survey of the DNA damage response in Caulobacter crescentus
Proteomic survey of the DNA damage response in Caulobacter crescentus
ABSTRACT The bacterial DNA damage response is a critical, coordinated response to endogenous and exogenous sources of DNA ...
Watching DNA uptake: B. subtilis joins the crowd
Watching DNA uptake: B. subtilis joins the crowd
ABSTRACT J. D. Zuke, R. Erickson, K. R. Hummels, and B. M. Burton (J Bacteriol 205:e00156-23, 2023, https://doi.org/10.112...
Visualizing dynamic competence pili and DNA capture throughout the long axis of Bacillus subtilis
Visualizing dynamic competence pili and DNA capture throughout the long axis of Bacillus subtilis
ABSTRACT The first step in the process of bacterial natural transformation is DNA capture. Although long hypothesized base...
The mef(A)/msr(D)-carrying streptococcal prophage Φ1207.3 encodes an SOS-like system, induced by UV-C light, responsible for increased survival and increased mutation rate
The mef(A)/msr(D)-carrying streptococcal prophage Φ1207.3 encodes an SOS-like system, induced by UV-C light, responsible for increased survival and increased mutation rate
ABSTRACT Bacterial SOS response is an inducible system of DNA repair and mutagenesis. Streptococci lack a canonical SOS re...
Myxococcus xanthus PilB interacts with c-di-GMP and modulates motility and biofilm formation
Myxococcus xanthus PilB interacts with c-di-GMP and modulates motility and biofilm formation
ABSTRACT The regulation of biofilm and motile states as alternate bacterial lifestyles has been studied extensively in fla...
Small regulatory RNAs are mediators of the Streptococcus mutans SloR regulon
Small regulatory RNAs are mediators of the Streptococcus mutans SloR regulon
ABSTRACT Dental caries is among the most prevalent chronic diseases worldwide. Streptococcus mutans, the chief causative a...
The microbial-derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota
The microbial-derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota
ABSTRACT Clostridioides difficile is a Gram-positive, spore-forming anaerobe that causes clinical diseases ranging from di...
Three genes controlling streptomycin susceptibility in Agrobacterium fabrum
Three genes controlling streptomycin susceptibility in Agrobacterium fabrum
ABSTRACT Streptomycin (Sm) is a commonly used antibiotic for its efficacy against diverse bacteria. The plant pathogen Agr...
Ribosome heterogeneity results in leader sequence-mediated regulation of protein synthesis in Francisella tularensis
Ribosome heterogeneity results in leader sequence-mediated regulation of protein synthesis in Francisella tularensis
ABSTRACT Although ribosomes are generally examined in aggregate, ribosomes can be heterogenous in composition. Evidence is...
A Family of Spore Lipoproteins Stabilizes the Germination Apparatus by Altering Inner Spore Membrane Fluidity in Bacillus subtilis Spores
A Family of Spore Lipoproteins Stabilizes the Germination Apparatus by Altering Inner Spore Membrane Fluidity in Bacillus subtilis Spores
Bacterial spores exhibit extreme longevity and resistance to many killing agents, and are thus problematic agents of sever...
Subversion of the Complement System by Pseudomonas aeruginosa
Subversion of the Complement System by Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen heavily implicated in chronic diseases. Immunocompromised patients tha...
Mechanisms of Regulation of Cryptic Prophage-Encoded Gene Products in Escherichia coli
Mechanisms of Regulation of Cryptic Prophage-Encoded Gene Products in Escherichia coli
Cryptic or defective prophages have lost genes necessary to excise from the bacterial chromosome and produce phage progeny...
Famotidine Enhances Rifampicin Activity against Acinetobacter baumannii by Affecting OmpA
Famotidine Enhances Rifampicin Activity against Acinetobacter baumannii by Affecting OmpA
In this study, famotidine was discovered for the first time to have potential as an antibiotic adjuvant, enhancing the ant...
Identification of DraRS in Clostridioides difficile, a Two-Component Regulatory System That Responds to Lipid II-Interacting Antibiotics
Identification of DraRS in Clostridioides difficile, a Two-Component Regulatory System That Responds to Lipid II-Interacting Antibiotics
Clostridioides difficile is a major cause of hospital-acquired diarrhea and represents an urgent concern due to the preval...
The Arabinose 5-Phosphate Isomerase KdsD Is Required for Virulence in Burkholderia pseudomallei
The Arabinose 5-Phosphate Isomerase KdsD Is Required for Virulence in Burkholderia pseudomallei
The intrinsic resistance of B. pseudomallei to many antibiotics complicates treatment. This opportunistic pathogen possess...
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