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MPOX: Resilient Strategies in Prevention and Diagnosis
MPOX: Resilient Strategies in Prevention and Diagnosis
MPOX, a zoonotic orthopoxvirus, has resurged in recent years, culminating in extensive outbreaks in 2022 and 2024. The evo...
Models for Studying Fungal Pathogenesis
Models for Studying Fungal Pathogenesis
Fungal pathogens represent a serious cause of disease and death in immunodeficient and immunocompromised patients. The inc...
DNA Vaccines, an Innovative Vaccine Platform against COVID-19
DNA Vaccines, an Innovative Vaccine Platform against COVID-19
This review aims to provide a comprehensive overview of DNA vaccine platforms developed against SARS-CoV-2 after providing...
Fecal Microbiota Transplantation for Alzheimer’s Disease: a Review of Current Evidence and Future Perspectives
Fecal Microbiota Transplantation for Alzheimer’s Disease: a Review of Current Evidence and Future Perspectives
Alzheimer’s disease (AD) is the most common form of dementia, as well as an age-related, progressively worsening neu...
Human Cytomegalovirus-Induced Immune Tolerance in Glioma
Human Cytomegalovirus-Induced Immune Tolerance in Glioma
This paper investigates the role of Human Cytomegalovirus (HCMV) in promoting immune tolerance within gliomas, particularl...
The Role of Intracellular Bacterial Communities of Uropathogenic in Chronic Urinary Tract Infection and New Therapeutic Ideas
The Role of Intracellular Bacterial Communities of Uropathogenic in Chronic Urinary Tract Infection and New Therapeutic Ideas
Escherichia coli is the primary pathogen responsible for urinary tract infections (UTI), accounting for approximately 75% ...
Risk Factors of Anisakidosis at the Global Level: A Review
Risk Factors of Anisakidosis at the Global Level: A Review
This review builds upon previous global assessments of anisakidosis by focusing specifically on the diagnostic approaches ...
Seeing Through the Layers: Clinical, Immunological, and Diagnostic Advances in Ocular Herpesvirus Infections
Seeing Through the Layers: Clinical, Immunological, and Diagnostic Advances in Ocular Herpesvirus Infections
Ocular herpesvirus infections caused by HSV-1, HSV-2, VZV, and CMV can affect nearly every structure of the eye and remain...
Fungal Pathogenesis and Virulence in the Anthropocene: Multidimensional Impacts of Climate Change
Fungal Pathogenesis and Virulence in the Anthropocene: Multidimensional Impacts of Climate Change
This review explores understudied dimensions of climate change-fungal pathogenesis interactions, focusing on molecular mec...
Skin Sentinels: Defensive Effector Molecules Produced by the Skin Microbiome
Skin Sentinels: Defensive Effector Molecules Produced by the Skin Microbiome
This review examines how the human skin microbiome contributes to defense against infection through its production of anti...
Amoebic Colonization in Humans: the Role of Zoonotic Transmission in Infection Ecology
Amoebic Colonization in Humans: the Role of Zoonotic Transmission in Infection Ecology
Entamoeba histolytica is the primary causative agent of amebiasis, with transmission occurring mainly through contaminated...
Enhancing Multi-Sector Collaboration and Integrating Nature-Based Solutions for Better One Health Policy Outcomes
Enhancing Multi-Sector Collaboration and Integrating Nature-Based Solutions for Better One Health Policy Outcomes
This paper explores the critical role of multi-sector collaboration and integrated interventions within the One Health app...
Unfolded Protein Response: a Key Coordinator of Endoplasmic Reticulum Stress and Pathogenicity in Human Fungal Pathogens
Unfolded Protein Response: a Key Coordinator of Endoplasmic Reticulum Stress and Pathogenicity in Human Fungal Pathogens
The unfolded protein response (UPR) is essential for maintaining endoplasmic reticulum (ER) homeostasis during stress. In ...
COVID-19 and Mucosal Immunization: Assessing Current Efforts, Challenges, and Future Opportunities for Vaccine Development
COVID-19 and Mucosal Immunization: Assessing Current Efforts, Challenges, and Future Opportunities for Vaccine Development
This review aims to provide a comprehensive overview of the mucosal immune system and assess the potential of mucosal vacc...
Regulation and Therapeutic Intervention of Bacterial Biofilms
Regulation and Therapeutic Intervention of Bacterial Biofilms
Bacteria are highly adaptive organisms that have evolved various survival strategies to persist and thrive in hostile envi...
Host-vaginal microbiota interaction: shaping the vaginal microenvironment and bacterial vaginosis
Host-vaginal microbiota interaction: shaping the vaginal microenvironment and bacterial vaginosis
This review comprehensively examines host-vaginal microbiota interactions, the composition of the vaginal microbiota, and ...
SARS-CoV-2 Resistance to Small Molecule Inhibitors
SARS-CoV-2 Resistance to Small Molecule Inhibitors
SARS-CoV-2 undergoes genetic mutations like many other viruses. Some mutations lead to the emergence of new Variants of Co...
Update on the Regulation and Maintenance of Epstein-Barr Virus Latency
Update on the Regulation and Maintenance of Epstein-Barr Virus Latency
As the first identified human oncogenic virus, Epstein-Barr virus (EBV) is widely circulating in humans. EBV presents main...
Foodborne Helminthiasis
Foodborne Helminthiasis
This review focuses on key foodborne helminths: providing an overview of their lifecycles and major transmission routes to...
Modulation of Wnt Signaling Pathway during Cytomegalovirus Latency and Reactivation
Modulation of Wnt Signaling Pathway during Cytomegalovirus Latency and Reactivation
The Wnt signaling pathway is one of the key pathways involved in hematopoietic progenitor cell (HPC) proliferation and dif...
Molecular Mechanisms of KSHV Latency Establishment and Maintenance
Molecular Mechanisms of KSHV Latency Establishment and Maintenance
This review summarizes results from recent studies that shed light on viral and cellular mechanisms that contribute to lat...
Resistance Mechanisms to Amphotericin B Alternative Treatments Development
Resistance Mechanisms to Amphotericin B Alternative Treatments Development
Systemic fungal infections caused by Candida auris have been identified since 2009, with mortality rates and drug resistan...
Myeloid Cell Reservoirs: Role in HIV-Host Interplay and Strategies for Myeloid Reservoir Elimination
Myeloid Cell Reservoirs: Role in HIV-Host Interplay and Strategies for Myeloid Reservoir Elimination
Despite host antiviral responses and antiretroviral therapy, HIV-1 continues to persist in myeloid cell reservoirs. Hence,...
Virulence Traits in Commensalism and Disease
Virulence Traits in Commensalism and Disease
Candida albicans is a common constituent of the normal human microbiota of the oro-gastrointestinal and vaginal tract. The...
Integrating Genomic Data with the Development of CRISPR-Based Point-of-Care-Testing for Bacterial Infections
Integrating Genomic Data with the Development of CRISPR-Based Point-of-Care-Testing for Bacterial Infections
Bacterial infections and antibiotic resistance contribute to global mortality. Despite many infections being preventable a...
Agent-Based Models of Virus Infection
Agent-Based Models of Virus Infection
Agent-based modelling (ABM) is a robust computational tool for investigating the dynamics of infectious disease spread and...
Potential Influence of Antifungal-drug Resistant Pathogens in Patients with Cholangiocarcinoma and the Application of Nanoparticle Mechanisms as Novel Antifungal and Anticancer Agents
Potential Influence of Antifungal-drug Resistant Pathogens in Patients with Cholangiocarcinoma and the Application of Nanoparticle Mechanisms as Novel Antifungal and Anticancer Agents
Cholangiocarcinoma (CCA) is the most lethal and common malignant tumours that occur in the bile ducts. Although it is rela...
Machine Learning-based Host–Pathogen Protein–Protein Interaction Prediction
Machine Learning-based Host–Pathogen Protein–Protein Interaction Prediction
This review examines machine learning methods for host–pathogen protein–protein interaction (PPI) prediction. ...
Highly Dynamic Cytoskeletal Networks Support Productive Viral Infection and Host Innate Immune Response Activation
Highly Dynamic Cytoskeletal Networks Support Productive Viral Infection and Host Innate Immune Response Activation
Increasing evidence shows that the onset of the host cytoskeleton changes during the viral infection process. The attainme...
Emerging Roles of Modern Lifestyle Factors in Microbiome Stability and Functionality
Emerging Roles of Modern Lifestyle Factors in Microbiome Stability and Functionality
It is now evident that the microorganisms living on and inside the human body modulate a myriad of host responses and acti...
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